39 results about "Nicotine concentration" patented technology

The disclosure relates to an improved method of enhancing nicotine concentrations in a gaseous carrier. The methods are adaptable to the delivery of nicotine for therapeutic effect in various diseases, in particular nicotine for tobacco product use cessation, substitution and / or harm reduction. The disclosure further relates various devices and device design principles for practicing these methods.

A method for predicting nicotine replacement dosage to achieve a target nicotine serum concentration relies on measuring blood nicotine concentration prior to smoking cessation. At least two values corresponding to other patient characteristics, such as body mass, cumulative smoking, psychological dependence, age, and menopausal status, are also determined and used to predict expected blood nicotine concentrations based on nicotine replacement dosages. Such methods are useful in achieving target blood nicotine concentrations for smoking cessation and therapy.

The invention discloses a pseudomonas putida to metabolite nicotine, which is characterized by the following: preserving in China Typical Culture Preservation Center (Wuhan university, china Wuhan) with keeping number as CCTCC NO.M 205038; possessing stronger nicotine metabolic ability and nicotine toxin immunity ability; growing highest at 6g / L nicotine density; culturing a good deal of bacterial strain; using intact cell as biological activator; degrading nicotine from tobacco industrial waste water completely. This bacterium possesses simple operation and quick disposing waste water speed, which can be used to dispose the waste water from tobacco industrial widely.

The invention provides a new strain of nicotine degrading bacteria—Pseudomonas ZUTSKD and its application. Pseudomonas sp. ZUTSKD (Pseudomonas sp. ZUTSKD), preserved in China Center for Type Culture Collection, date of preservation is June 18, 2007, preservation number CCTCCNO: M 207083. The bacteria can degrade nicotine to produce intermediate products such as 2,3'-Bipyridine, cotinine, 3-(3,4-dihydro-2H-pyrrol-5-yl)-Pyridine and 3-Pyridinecarboxylic acid, and can tolerate the highest nicotine With a concentration of 5.5g / L, it can degrade nicotine in waste tobacco powder, and has a certain application prospect in industry.

A composition for administration to the nasal mucosa of a subject comprises a solution of nicotine or a pharmaceutically acceptable salt thereof in a pharmaceutically acceptable solvent. The composition has a nicotine concentration less than 0.08 mg / ml. The composition used alone assists in reduction of the desire of a subject to smoke tobacco. It also reduces the nasal symptoms associated with administration of higher concentrations of nicotine to the nasal mucosa.

A dosimetric smoke determination method used in a full-smoke exposure experiment is used for real-time and quantitative determination of smoke dosage in a full-smoke exposure bin through combination of a quartz micro balance wafer and an inserted cell culture dish. The method has the maximum characteristic that an actual microenvironment for smoke exposure is simulated, the actual concentration (including the mass concentration of smoke particulate matter and nicotine concentration) of cigarette smoke in the full-smoke exposure bin is detected in a real-time, sensitive and quantitative mode, the dosage-effect relation of a smoke toxicity effect is accurately represented, and a real smoke dosage basis is provided for evaluation of cigarette smoke in-vitro toxicology. By applying method, the toxicity mechanism of the cigarette smoke can be better interpreted, and a method basis and technical support are provided for health risk assessment and research of tobacco products. In addition, the method is wide in applicability and can be applied to in-vitro toxicity testing and research of cigarettes, electronic cigarettes, cigarettes non-combustible in heating and aerosols different in source, and testing results are good in repeatability, high in stability and strong in sensitivity.

The invention discloses a nicotine blended product, a preparation method of the nicotine blended product, and electronic cigarette tar. The nicotine blended product comprises nicotine, organic acid, asolvent and plum refined substance. According to the technical scheme provided by the invention, the concentration of nicotine in the cigarette tar can be effectively reduced, and meanwhile, the smoking satisfaction of a consumer can be satisfied.