The invention discloses cleaning and sterilizing equipment of a vacuum belt drying unit. The cleaning and sterilizing equipment comprises a plurality of discharge tanks, a rotor pump, a rotor pump liquid outlet pipeline, a plurality of discharge screw pumps, a plurality of discharge pipelines, a purified water tank, a concentrated alkaline preparation tank, an alkali-washing tank, an aggregate bin, a buffer tank, a liquid collector, a condenser, a vacuumizing unit, a speed reducer, a self-priming pump, a valve, a centrifugal pump, a tubular heat exchanger and a cleaning pump, and further comprises a vacuum belt drier, wherein the vacuum belt drier comprises several layers of track conveyor belts, a case, a track bracket, a heating plate bracket, and a plurality of heating plates and cleaning tube units. According to the cleaning and sterilizing equipment, the cleaning ability is enhanced, the sanitary dead angle is reduced, and the exhaustion of residual water is facilitated, so that interior of the equipment is completely and fully cleaned, and in addition, an installation method of an original track support bracket is optimized to facilitate disassembly; and with adoption of thecleaning and sterilizing equipment, a cleaning standard for the production is improved, pollution and cross pollution are simultaneously prevented and the product quality is guaranteed.