54results about How to "Small need" patented technology

The present invention relates to the identification of marker genes useful in the diagnosis and prognosis of clinically problematic subsets of primary breast cancers. More specifically, the invention relates to the identification of two sets of marker genes that are differentially expressed in and useful for the diagnosis and prognosis of subsets of hormone receptor-negative (HRneg; i.e., ER and PR negative) and triple-negative (Tneg; i.e., ER, PR and HER2 negative) primary breast cancers at highest risk for early metastatic relapse. The invention further provides methods for determining the best course of treatment for patients having one of these clinically problematic subsets of primary breast cancers. The invention also provides methods for identifying compounds that prevent or treat a subtype of breast cancer based on their ability to modulate the activity or expression level of one or more marker genes identified herein.

A method and a system for receiving streaming media from an external provider onboard a moving vehicle via wireless communication is disclosed. The method includes: checking, upon a request from a client device to obtain a streaming media from said external provider, whether a segment of said streaming media is available in the cache or not; forwarding, when a segment of the requested streaming media is available in the cache, the segment of the streaming media object to the client device from the cache; downloading, when the segment of the requested streaming media is not available in the cache, the segment of the streaming media object from the external server, and forwarding the downloaded segment to the client device, and storing the segment in the cache.

A gravity power generation mechanism utilizes a gravity energy conversion unit to convert the gravity potential energy into the kinetic energy. The gravity energy conversion unit produces positive torques by adopting outward-spreading single directional swing arms and reduces the negative torques by cooperating with the folding action of the single directional swing arms, so as to perform a long-time, effective and continuous energy conversion of converting gravity potential energy into the kinetic energy. Next, the kinetic energy will be transmitted to a power generating unit to perform another energy conversion of converting the kinetic energy into the electric energy. And finally, a power supply system is used to transmit the electric energy out. By such arrangements, the gravity power generation mechanism not only has the advantages, such as: more simplified in structure, higher conversion ratio, and more environment-friendly but only needs a little of starting energy to perform a long-time energy conversion.

In an apparatus and a method of producing a roll of bags, a feeding means is arranged to feed bags one by one to a winding station. The winding station includes a rotating spindle which is arranged to engage with each bag separately to wind the bag thereon, thereby building a roll of bags in which the bags are unconnected to one another yet firmly hold together.The apparatus can be of simple construction, which provides for low costs and little wear and tear. Further, there is little risk of inflicting damage to the bags. Additionally, the flow of separate bags can be directed between several sequentially operated winding stations, thereby allowing for high production rates.

An electric parking brake actuator has a transmission mechanism, which is rotationally drivable by an electric motor and converts rotational movement into an axial movement of an actuating rod that carries an actuating element for the parking brake. The actuating rod normally moves by electric motor displacement via the transmission mechanism from an unblocking position to a blocking position and vice versa. A blocking mechanism serves the purpose of holding the actuating rod in the unblocking position of the actuating rod against the force of a spring element. A blocking disc, which is in drive connection with the transmission mechanism, has a stop surface for a locking device in only one rotational direction of the blocking disc. For secondary alternate operation the stop surface is releasable by the locking device so that the actuating rod is biased by the spring element to the blocking position without electric-motorized assistance.

In the glass-ceramic composition, a weight ratio of a glass and a ceramic is 40 to 60:60 to 40. The glass is composed of 40 to 60 wt % of SiO2, 5 to 9 wt % of Al2O3, 1 to 10 wt % of B2O3, 3 to 5 wt % of Na2O+K2O, 3 to 15 wt % of CaO+MgO+ZnO, and 15 to 40 wt % of PbO, and does not contain Li2O. A softening point of the glass is 650 to 780° C. The circuit substrate includes a laminate substrate formed by laminating insulating substrates, and a conductor circuit formed on a surface of each insulating substrate. The insulating substrate is formed of the glass-ceramic composition. A wiring layer and a via hole conductor are provided inside the laminate substrate.

A communication server and accompanying communication devices allow near instantaneous communication between users of the communication devices. A communication device may be configured with multiple channels, where each channel is assigned a corresponding communication device. As the communication devices are registered with the communication server, each communication device has knowledge of other registered communication devices. Thus, communication devices may communicate nearly instantaneously with each other. Furthermore, as the communication device is equipped with multiple channels, a single communication device may host a conference call with other communication devices. In addition, communication device may include multiple buttons to control the communication device, and indicator lights to indicate the status of calls with other communication devices.

A method for treating impurities contained in exhaust gases of ships to reduce sulphur oxide and other emissions, includes scrubbing the exhaust gases in an exhaust gas scrubber and supplying wash water effluent exiting from the scrubber and containing impurities to a purification unit onboard a ship. In order for the method to purify wash water exiting the scrubber sufficiently enough to be discharged directly to sea, the purification unit includes a moving filter band, whereby an aqueous fluid containing impurities originating from the effluent is together with a precipitating agent fed to a surface of the inclined filter band and filtered there through to concentrate impurities onto the surface of the band filter as a precipitate. When necessary, the pH of the purified effluent is adjusted so that it is at least 6.5 before discharging the purified effluent into the sea or returning it to the exhaust gas scrubber.

There is disclosed a plasma processing apparatus for making a gas including hydrocarbon plasma and forming a film including carbons on an object to be coated with a film. The apparatus includes a first reaction chamber for performing a first plasma process on the object to be deposited, a second reaction chamber for performing a second plasma process on an exhaust gas after the first plasma process is performed, and an exhaust pump for exhausting a gas to the outside after the second plasma process is performed. The first reaction chamber is connected to the exhaust pump via the second reaction chamber.

An information record apparatus includes: a down-convert device for down-converting a first content information having a first reproduction quality (HD) into a second content information having a second reproduction quality (SD) which is lower quality than the first reproduction quality; a scramble device for generating scramble information by scrambling the first content information, on the basis of a predetermined scramble key; and a first record device for recording the second content information and the scramble information into a first record medium.

A transmission device (1) with a hydraulic system (4) comprising a main transmission pump device for supplying various transmission components with hydraulic fluid. The main transmission pump device is driven by torque applied to the transmission input shaft (2). A force flow between the transmission input shaft (2) and transmission output shaft (3) is produced by various hydraulically actuated transmission components. When the hydraulic system (4) is not supplied by the main transmission pump, the force flow is interrupted. The hydraulic system (4) has an auxiliary pump device (5) by virtue of which the hydraulic system (4) too can be supplied with hydraulic fluid. The auxiliary pump device (5) is driven by torque applied to the transmission output shaft (3) at least when the force flow is interrupted.

Apparatus with variable compression ratio and variable expansion ratio for an internal combustion engine, mounted on the engine crankshaft and the assembly of the piston-connecting rod, comprising an actuating motor, a worm, a worm gear, a sun gear, a first transmission shaft, a plurality of the transmission shafts, a first eccentric sleeve, a plurality of eccentric sleeve, a front gear of the first eccentric sleeve, a plurality of the front gear of the eccentric sleeve, a plurality of the rear gear of the eccentric sleeve, a planetary gear, the rear gear of the first transmission shaft, a plurality of the front gear of the transmission shaft, and a plurality of the rear gear of the transmission shaft. An angle α between the axis of the first transmission shaft and the axis of the crankshaft is not zero, the other axes of the transmission shafts with the axis of the crankshaft coincide, or parallel but do not coincide, or form a non zero angle.

A garage appliance control system includes: at least one appliance installed in a garage that is provided as a portion of a building or a garage that is provided adjacent to the building; a first light emission portion which is provided in a vehicle that is parked in the garage, and which emits visible light; a first light reception portion that is provided in the garage, and that receives visible light emitted from the first light emission portion; and a control portion that controls the appliance based on light reception by the first light reception portion.

A method and an arrangement are provided for monitoring the safety of a counterweighted elevator. In the method, an elevator car is driven with a hoisting machine towards the top end of the elevator hoistway, contact between the counterweight and the end buffer of the elevator hoistway is determined, a reference point for the location of the elevator car is registered when detecting contact between the counterweight and the end buffer, the distance that the elevator car travels onwards from the aforementioned reference point for the location is measured, and if the distance traveled by the elevator car onwards from the aforementioned reference point exceeds a threshold value a signal indicating a risk of slackening of the traction rope is formed.

In accordance with the present invention, an x-ray diffraction apparatus and method are provided in which an x-ray or goniometer head can be adjusted in different directions to allow the head to direct x-rays at a part from various positions. In this manner, measurements can be taken from a wider region of the part without requiring that the part itself be moved or that an operator move the unit, which can be relatively heavy. In one aspect, the head can be rotated about its internal axis so that it can more readily direct x-rays along curved surfaces of parts while keeping a substantially constant distance therefrom. It is preferred that the apparatus be a portable unit including adjustment mounts to allow the x-ray head to be moved in the different directions so that it can be transported for use in the field at the site at which a part is located. In this instance, the unit allows for measurements to be taken from the part while it remains in service. Accordingly, the present portable unit allows for x-ray diffraction techniques to be used on parts where it is not practical or economic to remove them from service, such as cables or wire ropes used as tension members for bridges. Moreover, the preferred portable x-ray diffraction unit herein provides an easy to interpret readout of the results of its measurements by generating a map at the part site so that, for example, any abnormalities in stress measurements taken will be highlighted in comparison to adjacent points on the map where more normal measurements are shown.

A control method wherein sliding of a sliding door by a powered sliding device is started after sounding an annunciation buzzer when an operating switch is operated, but when a remote control transmitter integrally having an ignition key is operated, the sliding of the sliding door by the powered sliding device is started without operating the annunciation buzzer.

An oral appliance intended to treat bruxism, snoring, apnea, TMJ and/or palatal lift with a retention line member that uses the interproximal embrasure space between adjacent teeth of the patient user to secure the appliance within the oral cavity as the patient user sleeps. The shape and position of the inter-proximal embrasure space prevents an attached retention line member from dislodging while the user is asleep but permits removal of the appliance upon waking.

A towed vessel suitable for containing and transporting various liquids is disclosed. The vessel further comprises various features useful in the transportation, navigation, and storage of the towable vessel, both when in use for transporting fluids and when transported in an emptied state. Such features include navigational and positioning devices and methods, power supply devices and methods, and means for filling, inflating, emptying, and deflating a non-rigid, towed vessel. Aspects of embodiments of the present invention further include features useful for purifying or preserving the purity of the fluid to be transported.

Printing machine with a machine frame (10) and at least two cylinders (16, 20) which cooperate during printing, and which are mounted in a framing (12, 14; 24) formed by the machine frame (10). The framing (12, 14; 24) includes a material which has, at least in a direction transverse to the axes of rotation on the cylinders (16, 20), a linear thermal expansion coefficient that is less than 2×10⁻⁶ K−¹. The material can be a composite material, particularly a carbon fiber reinforced plastic.