37results about How to "Use of type" patented technology

An orthotic trauma device is provided including an elongated orthosis body adapted to be wrapped around a portion of a body of a wearer of the device, the orthosis body being formed of a pliant material which is adapted to be easily cut with cloth-cutting scissors; a detachable fastening device provided at distal ends of the elongated orthosis body to releasably secure the distal ends to one another; and means for adjusting the tightness of the orthosis body operatively associated with the detachable fastening device. A pulley system for use in an orthotic device is also provided including a pair of pulley banks arranged in juxtaposed relationship, a first bank of which is adapted to be detachably disposed on a first distal end of an elongated orthosis body and a second bank of pulleys adapted to be detachably disposed on a second distal end of the elongated orthosis body; and a cable interconnecting the two pulley banks and running through a pulley on each of the pulley banks in alteration, such that shortening of the cable pulling the pulley banks together and tightening the orthotic device with the aid of a mechanical advantage dependent upon the number of pulleys mounted on each of the pulley banks.

The preferred embodiments are directed to small molecule inhibitors that are cellular proliferation inhibitors and thus are useful as anticancer agents. The small molecules have the general formulas that include a phenylbenzimidazole core ring.

The subject invention relates to a set of DNA primers which, when utilized in conjunction with the polymerase chain reaction (PCR) assay, can amplify and speciate DNA from five medically important Candida species. Furthermore, the PCR amplified products, generated by the primers, can also be used to create species specific probes which can also detect and confirm the five species of Candida. Thus, the present invention allows for early diagnosis and treatment of an infection. The assay is useful in the context of monitoring antifungal treatment regimens, screening potential antifungal agents, and similar applications requiring quantitative determinations.

A muffler for reducing the sounds of combustion gases exhausted from an internal combustion engine including an elongated fluid passage extending between an inlet and an outlet such that the outlet is in fluid communication with the inlet. Further, the inlet being connectable with the gases exhausted from the engine and the outlet being connectable with the atmosphere. The muffler further including an outer tank surrounding the passage and a tubular connector having a first end in fluid connection with the passage and a second end in fluid connection with the tank such that the connector produces a fluid connection between the passage and the tank. The connectors having a perforated resistance plate to restrict the fluid flow between said passage and said sound chamber thereby reducing the severity of the sound or fluid pulses entering and exiting said sound chamber, perforations in said perforated plate forming an open portion of said plate and said open portion being less than 60 percent.

A trigger actuated cleaning device includes an adjustable retainer assembly for alternately holding a full-size or compact aerosol spay canister, thereby allowing the device to be used as a mop with an extension wand and a large canister or a wandless hand-held device with a small canister. The retainer has a “ski-boot” configuration with a heel assembly slidable on a fixed rail having a spring biased latch engaging the rim at the bottom of the canister and clamping it against a toe stop, which is configured to align the canister with a trigger operated actuator. The heel assembly slides and locks in position for either a full-size or compact canister to snap into the device. The canister is removed by depressing a thumb operated release lever which clears the latch from the canister.

System and method for a patient controlled electronic (client-server) medical record system that can be used by patients, various healthcare professionals, and even emergency medical services. Patients set up the system, own and control the data, and authorize selected healthcare professionals to enter notes and other medical records (which may be imported from various legacy medical record systems) into the patient controlled system. The healthcare professionals can also retrieve data from the system according to various levels of patient authorization. Security is maintained using a combination of machine readable ID codes and patient PIN numbers, and emergency medical services personnel may also be granted at least lower level access to the system even without PIN codes, which is useful when patients are found in an unresponsive state. Other system functions, including automatic appointment scheduling, automated physician enrollment and referrals, and various messaging functions are also described.

An evaluation electronics system for a rotation-rate sensor, having a first and a second seismic mass, is developed for the purpose of ascertaining a rotation rate, acting on the rotation-rate sensor, from a deflection of the first and second seismic masses. The evaluation electronics system, in this instance, has a regulation member in order to minimize an undesired deflection of the first and second seismic masses, caused by interference influences.

An inkjet ink is provided, which includes a pigment dispersion containing an organic dispersant, a black pigment having an average particle diameter of not more than 200 nm, and a resinous dispersing agent, the organic dispersant being formed of at least one polymerizable compound, and the black pigment being included therein at an amount ranging from 2 to 30% by weight based on the organic dispersant, and an ionic compound. A ζ-potential of the black pigment to the at least one polymerizable compound of the organic dispersant is confined within the range of −10 mV to +100 mV.

An electronic throttle valve system more suitable for use in straddle type vehicles. A straddle type vehicle has an electronic throttle valve system for adjusting the amount of intake air to an internal combustion engine. The electronic throttle valve system includes a throttle valve, an electric motor and a control unit. A guard mechanism is provided on a valve shaft of the throttle valve. The guard mechanism includes a pulley with which the throttle cable is engaged and a lever pulley which rotates in conjunction with the opening of the pulley. A cushion spring is provided on an edge face of a notched portion of the lever pulley, the edge face generally coming into contact with a protrusion that extends from the valve shaft of the throttle valve.

Disclosed is a gymnastics apparatus renovation kit including a cover adapted to fit tightly on a gymnastics apparatus to be renovated. The cover has an elongated shape extending in a longitudinal direction, the elongated shape corresponding to the shape of a gymnastics apparatus. The cover includes an upper face, two longitudinal lateral faces, two end faces, and an open lower face. The renovation kit also includes two rods, each rod being passed in a hem formed at the bottom of each lateral face of the cover and extending throughout the length of the cover. The renovation kit further includes links for joining the rods together in a transversal direction, tending to bring the rods closer together. Also disclosed is a corresponding renovation process and to a renovated gymnastics apparatus.

The present invention is directed to therapeutic compounds which have dual activity as agonists of GPR119 and inhibitors of DPP-IV and are useful for the treatment of metabolic disorders including type II diabetes.

A reticle cassette includes a bottom panel (1), a frame (2) arranged on the bottom panel (1), and a top cover (3) arranged on the frame (2), the bottom panel, the frame and the top cover defining a chamber with an opening, the reticle cassette further providing a door panel (4) at one side of the opening. The bottom panel (1) is provided thereon with a plurality of reticle supporting posts each separated from the frame (2) by a lateral gap, and the frame (2) has a longitudinal cross-section comprising H-shaped structures. A web (21) and a bottom surface of the first vertical wall (22) are separated from the bottom panel (1) by vertical gaps. The gaps are arranged between the reticle supporting posts and the frame (2) so as to make the reticle cassette suitable for use with both vacuum suction type and physical clamping type handling forks to pick up the reticle. As the frame (2) has a longitudinal cross-section comprising H-shaped structures and the gaps are provided between the web (21) as well as the bottom surface of the first vertical wall (22) of the H-shaped structure of the frame (2) and bottom panel (1), the reticle cassette can adapt not only to a handling fork without reticle protection but also to a handling fork equipped with reticle protection to pick up the reticle. All of these greatly enhance its versatility.

The present invention is directed to therapeutic compounds which have activity as agonists of GPR119 and are useful for the treatment of metabolic disorders including type II diabetes.

The present invention provides compositions and methods for treating lysosomal storage disease characterized by elevation of RIP kinase in a subject in need thereof using at least one RIP kinase inhibitor.

Biomarkers and methods using the biomarkers for classifying cancer in a patient (e.g., predicting the risk of cancer-specific death or cancer recurrence) are provided.