37results about How to "Use of type" patented technology

An apparatus for sampling tissue includes a tissue engaging member for engaging and retaining a sample of a tissue structure, and a cutter surrounding the tissue engaging member. The tissue engaging member and cutter are both operative to translate longitudinally with respect to one another, and a mechanism prevents the cutter from moving distally, the mechanism being released and the cutter freed to move distally when the tissue engaging member is in a predetermined position, preferably distal of the cutter. Thereby, out of sequence operation, e.g., premature cutting of the tissue before the tissue engaging member is in position, is prevented.

An orthotic trauma device is provided including an elongated orthosis body adapted to be wrapped around a portion of a body, the orthosis body being formed of a pliant material be easily cut with cloth-cutting scissors; a detachable fastening device provided at distal ends of the elongated orthosis body to releasably secure the distal ends to one another; and means for adjusting the tightness of the orthosis body operatively associated with the detachable fastening device. A pulley system for use in an orthotic device includes a pair of pulley banks arranged in a first and second of the pair of pulley banks detachably connected to a first distal end and a second distal end of the orthosis body respectively, a first bank of which is adapted to be detachably disposed on a first distal end of an elongated orthosis body and a second bank of pulleys adapted to be detachably disposed on a second distal end of the elongated orthosis body; and a cable interconnecting the two pulley banks and running through a pulley on each of the pulley banks in alteration, such that shortening of the cable pulls the pulley banks together and tightens the orthotic device with the aid of a mechanical advantage.

A rack rail assembly having an adjustable length that can be installed, without any tools or loose hardware, into a rack having mounting holes that are square or circular. It is also preferred that the rack rail assembly be reversible and able to support sliding and fixed deployment modes as well as cable mounting equipment. Accordingly, one preferred embodiment of the rack rail assembly comprises inner and outer rail members that are slidingly engaged. The rail members are adjustable lengthwise to be able to be used with various depth racks. The assembly further comprises a primary locking mechanism that locks the rails together at the desired length. The primary locking mechanism is further coupled to a biasing mechanism that allows the rails to be compressed for installation within a rack. Each end of the rail assembly has at least two pins that interface with mounting holes located in the rack. Preferably, the pins are capable of interfacing with circular or rectangular mounting holes. The rail assembly further comprises a secondary locking mechanism that locks the inner and outer rail together once the rail assembly is installed in the rack. The rack rail assembly further provides attachment points so a deployment rail can be installed once the rail assembly is installed on the rack. Depending on the desired application, either a sliding or a fixed deployment rail can be installed. The rail assembly also includes mounting point for cable management equipment.

An orthotic trauma device is provided including an elongated orthosis body adapted to be wrapped around a portion of a body of a wearer of the device, the orthosis body being formed of a pliant material which is adapted to be easily cut with cloth-cutting scissors; a detachable fastening device provided at distal ends of the elongated orthosis body to releasably secure the distal ends to one another; and means for adjusting the tightness of the orthosis body operatively associated with the detachable fastening device. A pulley system for use in an orthotic device is also provided including a pair of pulley banks arranged in juxtaposed relationship, a first bank of which is adapted to be detachably disposed on a first distal end of an elongated orthosis body and a second bank of pulleys adapted to be detachably disposed on a second distal end of the elongated orthosis body; and a cable interconnecting the two pulley banks and running through a pulley on each of the pulley banks in alteration, such that shortening of the cable pulling the pulley banks together and tightening the orthotic device with the aid of a mechanical advantage dependent upon the number of pulleys mounted on each of the pulley banks.

The preferred embodiments are directed to small molecule inhibitors that are cellular proliferation inhibitors and thus are useful as anticancer agents. The small molecules have the general formulas that include a phenylbenzimidazole core ring.

The subject invention relates to a set of DNA primers which, when utilized in conjunction with the polymerase chain reaction (PCR) assay, can amplify and speciate DNA from five medically important Candida species. Furthermore, the PCR amplified products, generated by the primers, can also be used to create species specific probes which can also detect and confirm the five species of Candida. Thus, the present invention allows for early diagnosis and treatment of an infection. The assay is useful in the context of monitoring antifungal treatment regimens, screening potential antifungal agents, and similar applications requiring quantitative determinations.

A muffler for reducing the sounds of combustion gases exhausted from an internal combustion engine including an elongated fluid passage extending between an inlet and an outlet such that the outlet is in fluid communication with the inlet. Further, the inlet being connectable with the gases exhausted from the engine and the outlet being connectable with the atmosphere. The muffler further including an outer tank surrounding the passage and a tubular connector having a first end in fluid connection with the passage and a second end in fluid connection with the tank such that the connector produces a fluid connection between the passage and the tank. The connectors having a perforated resistance plate to restrict the fluid flow between said passage and said sound chamber thereby reducing the severity of the sound or fluid pulses entering and exiting said sound chamber, perforations in said perforated plate forming an open portion of said plate and said open portion being less than 60 percent.

A trigger actuated cleaning device includes an adjustable retainer assembly for alternately holding a full-size or compact aerosol spay canister, thereby allowing the device to be used as a mop with an extension wand and a large canister or a wandless hand-held device with a small canister. The retainer has a “ski-boot” configuration with a heel assembly slidable on a fixed rail having a spring biased latch engaging the rim at the bottom of the canister and clamping it against a toe stop, which is configured to align the canister with a trigger operated actuator. The heel assembly slides and locks in position for either a full-size or compact canister to snap into the device. The canister is removed by depressing a thumb operated release lever which clears the latch from the canister.

System and method for a patient controlled electronic (client-server) medical record system that can be used by patients, various healthcare professionals, and even emergency medical services. Patients set up the system, own and control the data, and authorize selected healthcare professionals to enter notes and other medical records (which may be imported from various legacy medical record systems) into the patient controlled system. The healthcare professionals can also retrieve data from the system according to various levels of patient authorization. Security is maintained using a combination of machine readable ID codes and patient PIN numbers, and emergency medical services personnel may also be granted at least lower level access to the system even without PIN codes, which is useful when patients are found in an unresponsive state. Other system functions, including automatic appointment scheduling, automated physician enrollment and referrals, and various messaging functions are also described.

A transportable storage container assembly for transport by a tow vehicle. The assembly includes a trailer having a center rail with a two-point trailer hitch at the front end and a pivotable single wheel at the rear end. The trailer has a first cross channel adjacent the front end of the rail and a second cross channel adjacent the rear end of the rail. A storage container mounted on the trailer includes bottom support skids at each end that seat in the cross channels and are secured in the channels by casters that are attached to the skids through mounting holes in the cross channels. There is a jack on the bottom of the trailer rail movable along the length of the rail to facilitate the raising of the trailer for attachment to, and disattachment from, the tow vehicle trailer hitch.

An inkjet ink is provided, which includes a pigment dispersion containing an organic dispersant, a black pigment having an average particle diameter of not more than 200 nm, and a resinous dispersing agent, the organic dispersant being formed of at least one polymerizable compound, and the black pigment being included therein at an amount ranging from 2 to 30% by weight based on the organic dispersant, and an ionic compound. A ζ-potential of the black pigment to the at least one polymerizable compound of the organic dispersant is confined within the range of −10 mV to +100 mV.

An evaluation electronics system for a rotation-rate sensor, having a first and a second seismic mass, is developed for the purpose of ascertaining a rotation rate, acting on the rotation-rate sensor, from a deflection of the first and second seismic masses. The evaluation electronics system, in this instance, has a regulation member in order to minimize an undesired deflection of the first and second seismic masses, caused by interference influences.

An inkjet ink is provided, which includes a pigment dispersion containing an organic dispersant, a black pigment having an average particle diameter of not more than 200 nm, and a resinous dispersing agent, the organic dispersant being formed of at least one polymerizable compound, and the black pigment being included therein at an amount ranging from 2 to 30% by weight based on the organic dispersant, and an ionic compound. A ζ-potential of the black pigment to the at least one polymerizable compound of the organic dispersant is confined within the range of −10 mV to +100 mV.

An electronic throttle valve system more suitable for use in straddle type vehicles. A straddle type vehicle has an electronic throttle valve system for adjusting the amount of intake air to an internal combustion engine. The electronic throttle valve system includes a throttle valve, an electric motor and a control unit. A guard mechanism is provided on a valve shaft of the throttle valve. The guard mechanism includes a pulley with which the throttle cable is engaged and a lever pulley which rotates in conjunction with the opening of the pulley. A cushion spring is provided on an edge face of a notched portion of the lever pulley, the edge face generally coming into contact with a protrusion that extends from the valve shaft of the throttle valve.

A muffler for reducing the sounds of combustion gases exhausted from an internal combustion engine. The muffler including an elongated fluid passage extending between an inlet and an outlet such that the outlet is in fluid communication with the inlet. The inlet of the muffler being connectable with the gases exhausted from the engine and the outlet being connectable with the atmosphere. The passage having a first side region and a second side region circumferentially spaced from the first region with a fluid passage in at least one of the first and second side regions. The muffler further including a side attenuation sound chamber adjacent the at least one of the side regions wherein the chamber is circumferentially spaced from the other of the at least one side region.

Disclosed is a gymnastics apparatus renovation kit including a cover adapted to fit tightly on a gymnastics apparatus to be renovated. The cover has an elongated shape extending in a longitudinal direction, the elongated shape corresponding to the shape of a gymnastics apparatus. The cover includes an upper face, two longitudinal lateral faces, two end faces, and an open lower face. The renovation kit also includes two rods, each rod being passed in a hem formed at the bottom of each lateral face of the cover and extending throughout the length of the cover. The renovation kit further includes links for joining the rods together in a transversal direction, tending to bring the rods closer together. Also disclosed is a corresponding renovation process and to a renovated gymnastics apparatus.

A garden edging including a corrugated strip of sheet metal and a guard capping the corrugated strip. The guard includes a metal clip having a crosspiece from the opposite ends of which a pair of legs extends downwardly in the form of an inverted “U”. A plastic coating covers the clip. The coating is formed so as to have a pair of ribs that project inwardly toward one another from the bottoms of the legs for gripping the corrugated strip.

The present invention is directed to therapeutic compounds which have dual activity as agonists of GPR119 and inhibitors of DPP-IV and are useful for the treatment of metabolic disorders including type II diabetes.

Methods and apparatus for detecting local maximums in a two-dimensional data set. Apparatus is provided for detecting a local maximum in a two-dimensional data set, where a stream of data elements represents the data set. The apparatus includes first detection logic that receives the data stream and operates to detect a first data element that represents a peak in a first dimension of the data set. The apparatus also includes second detection logic that receives the data stream and operates to detect a second data element that represents a peak in a second dimension of the data set, wherein a local maximum is detected if the first and second data elements are the same element.

The invention relates to a system (10) for attaching to the stomach (24) of a pregnant woman, said system comprising a bracket (11) and strapping means; wherein said bracket comprising strapping engaging means (16) for releasable engaging said strapping means with said bracket (11) and / or for adjusting the effective length of said strapping means; wherein said bracket (11) either comprising a monitoring device (12); or comprising means for accommodating a separate monitoring device (12); wherein said strapping means comprise two separate straps (18) each having two ends; wherein one end of each of said separate straps (18) being an adhesive end (20) for adhering onto the skin of said woman's stomach (24).

An optical fiber ribbon splitting tool for selectively separating optical fibers of an optical fiber ribbon into one or more subsets of optical fibers. The ribbon splitting tool comprises a housing, a shearing device movably mounted within the housing, and an actuator for actuating the shearing device such that a subset of optical fibers is separated from the optical fiber ribbon. The shearing device may comprise a plunger having at least one shearing edge profile and a platen. A ribbon splitting tool for use at a cable access point of a fiber optic cable in which at least one optical fiber ribbon is accessible for splitting.

A reticle cassette includes a bottom panel (1), a frame (2) arranged on the bottom panel (1), and a top cover (3) arranged on the frame (2), the bottom panel, the frame and the top cover defining a chamber with an opening, the reticle cassette further providing a door panel (4) at one side of the opening. The bottom panel (1) is provided thereon with a plurality of reticle supporting posts each separated from the frame (2) by a lateral gap, and the frame (2) has a longitudinal cross-section comprising H-shaped structures. A web (21) and a bottom surface of the first vertical wall (22) are separated from the bottom panel (1) by vertical gaps. The gaps are arranged between the reticle supporting posts and the frame (2) so as to make the reticle cassette suitable for use with both vacuum suction type and physical clamping type handling forks to pick up the reticle. As the frame (2) has a longitudinal cross-section comprising H-shaped structures and the gaps are provided between the web (21) as well as the bottom surface of the first vertical wall (22) of the H-shaped structure of the frame (2) and bottom panel (1), the reticle cassette can adapt not only to a handling fork without reticle protection but also to a handling fork equipped with reticle protection to pick up the reticle. All of these greatly enhance its versatility.

The present invention is directed to therapeutic compounds which have activity as agonists of GPR119 and are useful for the treatment of metabolic disorders including type II diabetes.

The present invention provides compositions and methods for treating lysosomal storage disease characterized by elevation of RIP kinase in a subject in need thereof using at least one RIP kinase inhibitor.

Biomarkers and methods using the biomarkers for classifying cancer in a patient (e.g., predicting the risk of cancer-specific death or cancer recurrence) are provided.

A reticle cassette includes a bottom panel, a frame arranged on the bottom panel, and a top cover arranged on the frame, the bottom panel, the frame and the top cover defining a chamber with an opening, the reticle cassette further providing a door panel at one side of the opening. The bottom panel is provided thereon with a plurality of reticle supporting posts each separated from the frame by a lateral gap, and the frame has a longitudinal cross-section comprising H-shaped structures. A web and a bottom surface of the first vertical wall are separated from the bottom panel by vertical gaps. The gaps are arranged between the reticle supporting posts and the frame so as to make the reticle cassette suitable for use with both vacuum suction type and physical clamping type handling forks to pick up the reticle.