The invention relates to applications of pesticide active ingredient dicamba in inhibiting tobacco axillalry bud growth or in preparing a tobacco bud inhibitor. The invention also discloses a composition comprising another pesticide active component, wherein the pesticide active component is selected from uniconazole, trifluralin, prodiamine, flumetralin, pendimethalin, and butralin; and the weight ratio of dicamba to the pesticide active component ranges from 1:60 to 60:1. The pesticide active component can be made into a soluble liquid preparation, a micron emulsion, a water emulsion preparation, a suspending agent, a water dispersible particle preparation, a microcapsule preparation, a wettable powder, a missible oil, and the like. It is confirmed by experiments that the composition is used for inhibiting bud growth, and bud growth inhibiting effect is excellent, wherein dicamba is taken as the main active ingredient, and the composition is prepared from dicamba, the pesticide active component, and an auxiliary agent; no adverse influence on tobacco leaf chemical composition is caused by application of 40% of dicamba soluble liquid preparation, potassium content is increased, and tobacco leaf quality is improved.