The self-administration device is a standard chamber for laboratory mice designed to simulate the injection of addictive substances in humans. This device has two parts: hardware and
software. The hardware part includes five structures: the chamber, the
infusion pump, the food dispenser, the stimulator, and the controller (interface). The
software part controls the hardware parts and records events automatically. The chamber has three keys, each of which can be assigned to one of the effectors. To do this, we define in the device
software that pressing one key by the animal activates the
infusion pump, another key activates the feeder, and the third key does nothing in particular so that the animal's overall
motor activity can be measured with it. Above each key, there is an indicator lamp that, if programmed in the software, lights up each time the animal presses that key, signaling to the animal that the
drug is being injected or that the
truffle has been deposited in the bowl. In this way, in the long term, the animal learns which key to press if it wants to inject itself with a
drug, and which key to press if it wants to eat a
truffle. In this way, the state of
addiction to substances or food, as well as their interactions and the neural mechanisms associated with them, can be studied.