The invention relates to a safe and reliable saline injection machine for preserved meat production, which comprises a base, a saline tank, a liquid injection tube, a controller, a conveyor belt and an injection device. The injection device comprises a lifting mechanism, a lifting plate, an isolating mechanism and a plurality of injection mechanisms, the isolation mechanism comprises a direction adjusting assembly, a direction adjusting plate, a bottom plate, an ultraviolet lamp tube and two side plates. The direction adjusting assembly includes a direction adjusting unit and two hinge units,the injection mechanism includes a first motor, an adjustment plate, a sensing assembly, a plate, and an injection assembly. The safe and reliable saline injection machine can adjust the position of aneedle tube through the injection mechanism, avoids the bone in the meat, and prevents the tube from being excessively squeezed and damaged. After the injection is completed, the injection mechanismis isolated by the isolating mechanism, sterilization is carried out by irradiation of ultraviolet rays to prevent bacteria from infecting the infection, the safe processing and production of the meatfood is ensured, and the practicability of the machine is increased.