The invention discloses a breeding method of high-yield multi-resistance non-glutinous rice suitable for light simplified cultivation, which belongs to a breeding method of plant seeds. The method comprises the steps of generation segregation through early sowing at an early stage, screening through late sowing, high-density direct sowing, low-nitrogenous-fertilizer-level planting, direct sowing and mixed harvesting to obtain seeds which satisfy requirements. The rice bred through the method has the characteristics that the rice is suitable for light simplified cultivation, is high-yield and is multi-resistant. Under the transplanting condition of individual plants, the growth situation is good, the self-regulating capability is strong, the stem is robust, the rice is fertilizer-resistant and anti-falling, the rice can be directly planted in the early ten days and middle ten days of June, the spike length is generally and approximately 18cm, the number of productive spikes per mu can reach more than 200 thousand, the total grain number per spike is 130-140, the fruiting rate is above 90 percent, the weight per thousand grains is 27-28g, the rice grains are full, the commodity value is good and the processing quality is good.