34results about How to "Preventing and alleviating" patented technology

A composition and therapeutic kit including an aerosol packaging assembly including a container accommodating a pressurized product and an outlet capable of releasing a foamable composition, including a steroid as a foam. The pressurized product includes a foamable composition including: a container accommodating a pressurized product; and an outlet capable of releasing the pressurized product as a foam; wherein the pressurized product comprises a foamable composition including: i. a steroid; ii. at least one organic carrier selected from the group consisting of a hydrophobic organic carrier, a polar solvent, an emollient and mixtures thereof, at a concentration of about 2% to about 50% by weight; iii. a surface-active agent; iv. about 0.01% to about 5% by weight of at least one polymeric additive selected from the group consisting of a bioadhesive agent, a gelling agent, a film forming agent and a phase change agent; v. water; and vi. liquefied or compressed gas propellant at a concentration of about 3% to about 25% by weight of the total composition. The composition further may include a therapeutically active foam adjuvant, selected from the group consisting of a fatty alcohol, a fatty acid, a hydroxyl fatty acid; and mixtures thereof.

An apparatus adapted to inhibit pain signals generated by pain receptors in the skin during a skin related medical treatment such as an injection. An evacuation chamber is provided with an essentially rigid interface element through which a medical treatment can be administered to a selected skin region, one or more walls which are placeable on, or in the vicinity of, the skin region, an interior defined by the walls and by the interface element, and an opening at the bottom of the interior which is sealable by the skin region. A device generates a vacuum within the evacuation chamber interior to a level suitable for drawing the skin region through the opening towards, and in a compressing relation against, the interface element, to inhibit the transmission of a pain signal generated by pain receptors located within the skin region.

An improved composition and method is provided for preventing or alleviating lost circulation during the drilling of wellbores in subterranean formations, and particularly during the drilling of oil and gas wells. The method is suited for horizontal and directional wells as well as more vertical wells. The composition of the invention comprises a synergistic blend of resilient, angular, carbon-based material and a water-swellable, crystalline synthetic polymer. The method employs the composition of the invention in preventing lost circulation.

Disclosed herein is an oral care composition that provides pleasant cooling sensation and easy delivery of an oral care active ingredient. The tablet-type oral care composition of the present invention is prepared by compressing porous plastic granules at a pressure of 500 kg / cm2 or less and undergoes in situ melting and gelling by saliva or water in the buccal cavity, or by chewing. Upon direct administration of the composition to the buccal cavity, the composition undergoes melting and gelling by water or saliva, or by chewing action, and works to maintain oral health via gargling or mouth washing. Therefore, the formulation of the present invention advantageously reduces inconvenience of conventional liquid or ointment-like oral care products and also provides easy portability.

Disclosed therein is a high-functional shoe having functions for a pain alleviation and prevention of degenerative gonarthritis, which can alleviate a pain in the knee joint of a person, who suffers from degenerative gonarthritis or is injured in the knee joint by an abnormal lower limb joint movement, and prevent degenerative gonarthritis by uniformly dispersing a load biasedly applied to the knee joint. The high-functional shoe includes a shoe sole having a longitudinally sectional structure of a parallelogrammic form, and is applicable to persons, who have symptoms of degenerative gonarthritis.

The adjustable angle inlet for turbojet engines provides for the adjustment of the nacelle inlet as the angle of attack of the aircraft changes. The adjustable inlet system thus assures that the nacelle inlet is always oriented directly into the relative wind as the angle of attack of the aircraft changes, e.g., during takeoff, landing, and high-G maneuvers where the aircraft reaches relatively high angles of attack. The adjustable angle inlet is adaptable to most turbojet-powered airplanes, but is particularly well suited for use with aircraft having their engines mounted on lateral pylons on the rear of the fuselage. The system operates according to signals received from an angle of attack sensor. The sensor controls an actuator, which rotates a shaft that is connected to the pivotally mounted inlet of the engine nacelle.

The present invention relates to compositions containing an extract of processed Panax genus plant and saponin compounds isolated therefrom for treat the diseases caused by vascular injury in human or mammal, the method for treating said diseases using thereby and the use thereof. The extract of processed Panax genus plant and saponin compounds isolated therefrom shows suppressive effect on endothelial dysfunction and damage of blood-retinal on HUVEC and retinal vascular endothelial cell. Therefore, it can be used as the therapeutics or functional health food for treating and preventing the diseases caused by vascular injury.

The invention provides compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to normalize the level of serum glutamate-pyruvate Transaminase (GPT), or reduce serum HBsAg levels in a subject, said ability resulting from their having been cultured in the presence of an alternating electric field having a specific frequency and a specific field strength. Also provided are methods of making and using these compositions.

Linalool and other materials which are skin penetrating vasodilators or which can be made to have such properties are applied, either by themselves or in skin treatment compositions, to the skin of the head and especially the back of the neck to prevent or alleviate the effects of migraine headaches or applied to sore muscles or ligaments to aid in minimizing the soreness, or are applied to wrinkled and / or old looking skin on the face, neck, torso, or extremities, other than on the hands, to minimize wrinkles and / or improve the skin's appearance and / or are applied to the head to grow hair on the head or prevent hair loss.

The invention relates to a dietary supplement consisting of an aqueous extract of red vine leaves and an acceptable carrier which prevents and reduces the discomfort relating to mild-to-moderate chronic venous insufficiency of the legs.

The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.

The present invention relates to a use of a compound having ghrelin receptor agonistic activity, a pharmaceutically acceptable salt thereof or a pharmaceutical composition thereof for the manufacture of a medicament for treatment of diseases including achlorhydria in which abnormal gastric acid secretion is involved. In addition, the present invention relates to the method of treatment including administering to a human or animal. The compound, the pharmaceutically acceptable salt thereof, or pharmaceutical compositions containing them, may be used in combination with one or more second active agents. Further, the present invention relates to pharmaceutical compositions and kits comprising a compound of the present invention or a pharmaceutically acceptable salt thereof for the treatment of said diseases.

A method for treating viral infection includes administering to a subject in need thereof a composition containing P2X receptor antagonists. The methods may achieve preventive or therapeutic effect on hand foot and mouth disease by inhibiting viruses. The P2X receptor antagonists can inhibit infection by a positive-sense single-stranded RNA picornavirus. The virus may be an enterovirus or a Coxsackie virus, such as human enterovirus 71. The P2X receptor antagonist may be PPADS, iso-PPADS, PPNDS, Suramin, NF023, TNP-ATP, NF279, NF157, Evans Blue, an analog thereof, a derivative thereof, or a pharmaceutically acceptable salt thereof.

The present invention provides a composition capable of regulating the activity of autonomic nerves, by acting on these nerves, so as to maintain the homeostasis or alleviate disturbed homeostasis in an animal, wherein the above composition can be obtained from a naturally occurring substance in the nature by a simple process.The seawater mineral-containing composition of the present invention is characterized in that it contains seawater minerals obtained by treating seawater and is capable of regulating autonomic nerves. The seawater mineral-containing composition of the present invention preferably has a magnesium concentration of 70 mg / L or higher and a sodium concentration of 3 mg / L or lower.

A sensor device includes at least one autonomous streaming module. Predetermined internal events of the autonomous streaming module or predetermined external events from streaming data at an interface to a smart shell of the autonomous streaming module are detected. An operational mode of a component or subsystem within the smart shell of the autonomous streaming module is controlled in response to the detection.

The present invention relates to a sensor device or sensor node and a method of controlling operation of the sensor device, wherein the sensor device comprises at least one autonomous streaming module and wherein predetermined internal events of the autonomous streaming module or predetermined external events from streaming data at an interface to a smart shell of the autonomous streaming module are detected, and an operational mode of a component or subsystem within the smart shell of the autonomous streaming module is controlled in response to the detection.

The present invention relates to an antimicrobial compound having high safety as well as potent antimicrobial activity on a broad range of microorganisms represented by the following formula:

The present invention relates to a method of evaluating cellulite using fibulin-3 and / or sarcoglycan gamma as an indicator in a harvested skin sample, and a method of evaluating a drug for improving, preventing or treating cellulite using fibulin-3 and / or sarcoglycan gamma as an indicator in cultured cells.

A human amniotic fluid formulation has been developed for topical application to the eye, which is useful for the treatment of ocular diseases and injuries including dry eyes, Sjogren's Syndrome, cataracts, burns and injuries to the eye tissues. The formulation is a sterile de-cellularized human amniotic fluid (D-HAF), devoid of amniotic stem cells and elements of micronized membrane or chorion particles. Methods for treating, or preventing various ocular diseases, injuries and disorders using the formulation, optionally in combination with one or more therapeutic, prophylactic or diagnostic agents are described.

A human amniotic fluid formulation has been developed for topical application to the eye, which is useful for the treatment of ocular diseases and injuries including dry eyes, Sjogren's Syndrome, cataracts, burns and injuries to the eye tissues. The formulation is a sterile de-cellularized human amniotic fluid (D-HAF), devoid of amniotic stem cells and elements of micronized membrane or chorion particles. Methods for treating, or preventing various ocular diseases, injuries and disorders using the formulation, optionally in combination with one or more therapeutic, prophylactic or diagnostic agents are described.

Provided is use of a peptide, or a derivative of a peptide, in the manufacture of a medicament effective in stimulating fibroblasts to produce fibrillin,wherein the peptide comprises an amino acid sequence present in an α-S2 casein precursor, said sequence comprising 3 or more amino acids, and not comprising at its N-terminal amino acid of the full α-S2 casein precursor. Further provided is use of a peptide, or a derivative of a peptide, in the manufacture of a medicament effective in stimulating fibroblasts to produce fibrillin, wherein the peptide has an α-S2 casein fragment activity.

The present invention relates to novel benzofuran compounds, to pharmaceutical compositions that include such compounds, and to methods of use thereof. Certain compounds of the invention share some pharmacological properties with cannabinoids and have a common wide range of beneficial therapeutic indications. In particular, compounds of the invention are useful as analgesic, neuroprotective, immunomodulatory and anti-inflammatory agents.

A safety syringe structure includes a combined structure of a syringe barrel, a needle retreater, a needle, and a plunger. The needle retreater and the plunger are slidably received in the syringe barrel. The needle retreater is arranged adjacent to the front end of the syringe barrel. The needle is coupled to the needle retreater. The plunger has an end extended to form a sharp tip and is provided with a plug facing the needle retreater. The sharp tip extends outside the plug in a direction toward the needle retreater. The sharp tip is movable with the plunger toward the front end of the syringe barrel to pierce into and couple with the through hole of the needle retreater; and the sharp tip is movable with the plunger toward the rear end of the syringe barrel to drive, through the needle retreater, the needle into the channel.

The present invention relates to a pharmaceutical composition for treating dry eye syndrome, which comprises Gly-Tβ4 as an active ingredient, and the pharmaceutical composition restores damaged corneal epithelial cells and also has an effect of proliferating goblet cells, and thus is effective for treating, preventing, or alleviating dry eye syndrome.

A method for preventing, alleviating and / or treating idiopathic pulmonary fibrosis, which comprises administering an effective amount of a compound represented by formula (I), or a pharmaceutically acceptable salt, ester, stereoisomer, polymorph, solvate, N-oxide, isotope-labeled compound, metabolite or prodrug thereof to an individual in need thereof.

The present invention relates to a method of evaluating cellulite using fibulin-3 and / or sarcoglycan gamma as an indicator in a harvested skin sample, and a method of evaluating a drug for improving, preventing or treating cellulite using fibulin-3 and / or sarcoglycan gamma as an indicator in cultured cells.