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4 results about "Fibulin" patented technology

Fibulin (FY-beau-lin) (now known as Fibulin-1 FBLN1) is the prototypic member of a multigene family, currently with seven members. Fibulin-1 is a calcium-binding glycoprotein. In vertebrates, fibulin-1 is found in blood and extracellular matrices. In the extracellular matrix, fibulin-1 associates with basement membranes and elastic fibers. The association with these matrix structures is mediated by its ability to interact with numerous extracellular matrix constituents including fibronectin, proteoglycans, laminins and tropoelastin. In blood, fibulin-1 binds to fibrinogen and incorporates into clots.

Method for checking possibility of liver cancer onset

The present invention provides a method for testing a possibility of liver cancer development. A method for testing a possibility of liver cancer development includes step (1) of detecting at least one target molecule selected from the group consisting of Fibulin-3, GPNM3, Fibulin-3 mRNA, and GPNMB mRNA in a biological sample collected from a subject.
Owner:OSAKA UNIVERSITY

Application of fructus arctii extraction product

The invention relates to the technical field of preparation methods of cosmetic functional raw materials, in particular to application of a fructus arctii extraction product. The invention provides application of a fructus arctii extraction product in preparation of a product with the effect of improving the fiber structure order of a skin corium layer. According to the invention, a unique preparation process is adopted, and the active ingredients of phenolic acid and lignan substances are enriched, so that the expression of Fibulin-5, LOX, LOXL1 / 2 / 3, BMP1 and ADAMTS2 can be remarkably up-regulated by the fructus arctii extraction product, the ordered crosslinking of collagenous fibers is promoted, the activity of MMP-1 and MMP-12 is inhibited, the content of III-type collagen and elastin is increased, a multi-target and co-synergistic action mechanism is realized, and the effect of the fructus arctii extraction product is enhanced. Therefore, the potential of the fructus arctii extracted product for promoting ordered arrangement of fibers is improved, and reconstruction and reinforcement of a corium layer structure are realized on the molecular level.
Owner:BEIJING ACAD OF TCM BEAUTY SUPPLEMENTS CO LTD +1

Use of a rambutan extract for increasing the firmness of the skin and / or mucous membranes

The present invention relates to the use of various extracts of the plant of Rubus suavissimus S. Lee for increasing the firmness and / or elasticity of the skin and / or mucous membranes by increasing the gene and / or protein expression of collagen type I and / or collagen type V and / or LOX-L, perlecan-5, elastin-1 and / or fibrillin-1 in the skin and mucous membranes and / or reducing the CYR61 expression.
Owner:BASF BEAUTY CARE SOLUTIONS FRANCE SAS

Camellia mask capable of loading silk protein gel

ActiveCN224099696UCosmetic preparationsToilet preparationsCamellia japonica leafToxicology
The utility model relates to the technical field of facial mask production, and particularly discloses a camellia facial mask capable of loading silk polyprotein gel, which comprises a facial mask cloth body, a mouth hole, two eye holes and a breathing hole are arranged on the facial mask cloth body, a nasal mask is arranged at the breathing hole, the facial mask cloth body comprises a silk polyprotein gel layer, a camellia leaf fiber layer and a base cloth layer, the silk polyprotein gel layer, the camellia leaf fiber layer and the base cloth layer are arranged in a stacked mode, the adsorption layer is formed on the camellia leaf fiber layer through TEMPO oxidation or sulfate activation treatment, and the silk polyprotein gel layer is loaded on the camellia leaf fiber layer through the adsorption layer. The side, away from the silk polyprotein gel layer, of the camellia leaf fiber layer is connected with the base cloth layer, quercetin contained in camellia leaf fibers has a soothing function, the mask plays the skin repairing function of silk polyprotein, meanwhile, the anti-allergy soothing capacity and the moisturizing capacity are enhanced, and the sensitization rate is greatly reduced due to the natural attribute of the mask.
Owner:ZHONGKEJIMEI BIOTECHNOLOGY (CHONGQING) CO LTD