The invention discloses intermittent drying system and method of a multifunctional fluidized bed for freezing, spraying and pelleting, which has the advantages of flexible structure, variety methods, low use cost and the like. The structure is characterized by comprising a refrigeration system and a fluidized bed drying system for spraying and freezing in vacuum, wherein a vacuum spraying drying system is connected with a feeding system, the refrigeration system is connected with the feeding end of the vacuum spraying drying system, the other path of pipeline of the refrigeration pipeline is connected with a fluidized device of the vacuum spraying drying system through a pulse adjusting device to form a closed ring system, thereby flexible switch among different drying methods can be realized, and intermittent operation is carried out. The invention is mainly used for dewatering storage of products with high additional value, such as liquid foods, medicines, biological products and the like and development operation of new techniques of dewatering products such as liquid foods, medicines and biological products.