The invention relates to an automotive safety anti-omission reminding method based on RFID. The method comprises the following steps: when an automobile is started, an analysis control unit obtains and records the information about articles taken in the automobile through an RFID receiving reader; when the automobile stops, automobile information is detected so as to judge whether a person exists in the automobile or not; if yes, detection is performed circularly; if not, the analysis control unit is used for finding out whether an article needing to remind exists in the automobile or not; if yes, a notice is sent out so as to remind the driver; if not, no notice is sent; relevant information is cleared off. The invention further relates to a system applying the method. The system comprises an acquisition system, an analysis control unit, a pressure sensor, an RFID receiving reader, and articles to which RFID electronic labels are attached. Compared with the prior art, the method disclosed by the invention solves the problem that dangerous articles and important articles are left in the automobile, so that the possibility that the dangerous articles explode in the automobile under high temperature is eliminated, and the rate that valuables in the automobile are stolen is lowered. The RFID equipment and the sensor are low in cost, simple to realize, and high in practicability.