The invention discloses a subject visit management system and an automatic reminding method. The method comprises the following steps: perfecting information, and recording PM, CRC and basic personal information of a subject; adding clinical test items and visit information; configuring a project access window; managing a test research center; adding subjects, and filling in baseline dates of the subjects; automatically generating a subject visit schedule and a visit reminding record according to the collected information; visitors are reminded through WeChat, short messages and mails; after the CRC visits the testee, the visit state is changed into a visited state, and if the testee is not visited, the number of days of visit delay is set; and finally, access handover and access statistics are carried out. Through configuration management of clinical test item visit, an automatic visit reminding function is realized, and the problem of inconvenient management caused by a large number of visitors in traditional visit is solved.