The invention discloses spleen-tonifying qi-tonifying heat-clearing fire-lowering multi-flavor cookie, characterized by being made with, by weight, 300-400 parts of low-gluten flour, 60-80 parts of corn flour, 15-20 parts of sweet potato flour, 60-80 parts of watermelon, 2-2.5 parts of black sesame seed, 2-2.5 parts of white sesame seed, 50-65 parts of cream, 20-27 parts of milk powder, 60-80 parts of honey, 60-80 parts of egg, 3-4 parts of yeast powder, 3-10 part of baijiu, 15-20 parts of a nutrient additive and 5-6 parts of nutrient extracts. The invention also provides a making method of the spleen-tonifying qi-tonifying heat-clearing fire-lowering multi-flavor cookie. The spleen-tonifying qi-tonifying heat-clearing fire-lowering multi-flavor cookie and the making method thereof have the advantages that the making process is simple, the materials used herein are green, the cookie with multiple flavors of durian, watermelon, green bean and pear has the effect of body building, tonifying spleen and Qi and invigorating the kidney and strengthening Yang, and further is effective in clearing heat and fire, moistening lung and tonifying kidney, and nourishing yin and promoting body fluid, and the cookie is novel and unique, is suitable for different people to eat, especially for lovers and couples to eat together so as to improve their motional communication, and is new modern cookie.