8 results about "Baseline pressure" patented technology

A method of calibration of a drug delivery device including a pump, a fluid line, a reservoir, and a power source, includes actuating the pump a predetermined number of cycles to move fluid through the fluid line, determining an estimated pressure value within the fluid line for each cycle of the predetermined number of cycles, determining a baseline pressure level including an average of the estimated pressure values, delivering a discrete, predetermined volume of fluid through the fluid line via the pump, determining a delivery pressure value within the fluid line, determining a difference between the delivery pressure value and the baseline pressure level, and delivering a dose volume of fluid through the fluid line via the pump at a predetermined delivery profile based on the difference between the delivery pressure value and the baseline pressure level.

This invention discloses a method and system for accurately reproducing non-invasive blood pressure oscillation waveforms, relating to the field of vital sign data monitoring technology. It constructs and superimposes a target pressure sequence by separately generating a target baseline pressure curve and a target oscillation pressure curve. The actual pressure signal is then separated into an actual baseline pressure curve and an actual oscillation pressure curve. This allows the baseline pressure error and oscillation pressure error to correspond to the baseline pressure control quantity and oscillation injection control quantity, respectively, avoiding the problem of unclear error sources when correcting composite pressure as a whole. When reproducing the same target systolic pressure, target diastolic pressure, target mean pressure, and target heart rate multiple times, it can reduce pressure overshoot, pressure drop rate fluctuations, oscillation pressure amplitude distortion, and oscillation envelope peak position offset. This makes the corrected non-invasive blood pressure oscillation waveform closer to the target pressure sequence, improving the consistency of the error verification results and repeatability evaluation results of the non-invasive blood pressure module under test.

The invention discloses a respiration monitoring system and method based on local air pressure difference dynamic characteristics, and relates to the field of respiration monitoring. A compressed air source in the system is used for providing an air source; the mass flow controller is used for controlling the oxygen flow; an oxygen inhalation opening is formed in the tube wall of the oxygen inhalation tube; the position of the oxygen inhalation port is opposite to the connection point of the oxygen inhalation tube and the micro differential pressure sensor; the micro differential pressure sensor is used for measuring an air pressure difference signal between the internal pressure of the oxygen inhalation tube and the external atmosphere; the processing unit is connected with the micro-pressure sensor; the processing unit is used for acquiring a reference air pressure difference signal corresponding to a user in a non-breathing state and generating a baseline pressure curve; the processing unit is further used for determining the pressure difference deviation amount according to the real-time air pressure difference signal and the baseline pressure curve; and the breathing amplitude of the user is graded and evaluated according to the differential pressure deviation. Under the continuous oxygen supply condition, non-intrusive, low-cost and high-sensitivity real-time monitoring can be carried out on the breathing state.

The invention relates to the technical field of machine learning diagnosis, in particular to an esophagus high-resolution pressure measurement data intelligent diagnosis and risk assessment system based on machine learning, which comprises a data analysis module, a standard mapping module, a time alignment module, a function assessment module and a model correction module. According to the method, stable identification of key swallowing time nodes is realized through baseline pressure analysis and a swallowing period boundary generation mode, a pressure time sequence is promoted to complete standardized expression in a unified time scale, and the insufficient adaptability caused by dependence on fixed rules and manual annotation in existing processing is relieved; by constructing a resampling sequence under various time sampling conditions and carrying out dynamic time warping comparison, the recognition capability of dominant pressure change stages in different sampling states is enhanced, the judgment deviation caused by neglecting the time sequence consistency characteristic in the analysis process is made up, and sensor channels are screened in combination with esophageal axial pressure distribution.

The invention provides a postpartum hemostasis blood volume monitoring device and method, and the method comprises the steps: carrying out the spectrum analysis of a hydrostatic pressure time sequence signal, and determining a baseline pressure component of blood in a uterine cavity according to an analysis result and the frequency domain distribution difference between uterine contraction activity and hematocele; a pressure baseline threshold value is set according to postpartum initial stage information of the patient, and when the baseline pressure component continuously exceeds the pressure baseline threshold value, a primary trigger signal of abnormal rising of uterine cavity pressure is generated; in response to the primary trigger signal, starting an intracavity ultrasonic probe to perform fan-shaped scanning on the uterine cavity, obtaining a cross section echo image in the uterine cavity of the patient, and further identifying a liquid dark area between the boundary of the inner wall of the uterine cavity and the surface of a pressure sensor in the cross section echo image; and generating a uterine cavity hematocele alarm signal of the patient based on the maximum depth of the liquid area in the liquid dark area. By adopting the scheme of the invention, early warning lag caused by dependence on in-vitro bleeding amount statistics on the uterine cavity hematocele risk can be reduced.

A device for treating respiratory distress in a patient is disclosed. The device includes a pressure generator configured to deliver a positive pressure airflow to the patient's airway via a patient interface, a sensor configured to generate a signal representing the patient's respiratory flow, and a controller. The controller is configured to control the pressure generator to deliver ventilation therapy with baseline pressure and pressure support via the patient interface, detect apnea by the signal representing the patient's respiratory flow, control the pressure generator to deliver one or more probe breaths to the patient during the apnea, determine airway patency by the waveform of the respiratory flow signal in response to one of the one or more probe breaths, calculate the effective duration of the apnea based on the airway patency, and adjust a setpoint of the baseline pressure for the ventilation therapy in response to the apnea based on the effective duration of the apnea.

This invention relates to the fields of analytical detection and online solid-phase extraction technology, specifically to a rapid detection method for trace plasma samples used in pharmacokinetic studies. The method first measures the empty baseline pressure; after injection, it calculates the net sample pressure and total resistance integral in real time, and identifies the transition point from injection to cleaning to lock the fluid dynamics boundary parameters; during the cleaning phase, it calculates the measured pressure decay rate and extrapolates the theoretical pressure decay rate under ideal emptying conditions, uses the total resistance integral to compensate for viscosity at the measured rate, and then obtains the flow hysteresis ratio characterizing the sample matrix retention effect based on both; finally, it uses the flow hysteresis ratio to adaptively correct a standard threshold to obtain a target threshold, and performs flow path switching when the measured rate reaches the target. This invention effectively decouples sample viscosity from adsorption characteristics, enabling adaptive adjustment of the cleaning time based on real-time sample kinetic feedback, completely eliminating matrix residue contamination while ensuring the recovery rate of polar drugs.

An apparatus (10) for use in monitoring uterine contractions. Means are provided for detecting (18) secure (e.g. flush) contact of at least part of a sensor unit (14) of the apparatus on the abdomen and for detecting (20) an initial starting pressure or baseline pressure between the sensor unit and the abdomen. A controller (24) is arranged to first sense contact of said at least part of the sensor unit on the abdomen and then, in response to the contact detection, to detect the starting pressure using an integrated pressure sensor. The same pressure sensor is preferably used to monitor uterine contractions. The starting pressure provides a direct or indirect measure or indication of the tension of a belt arranged to hold the apparatus against the abdomen of the subject in use. By sensing the starting pressure, for example directly in response to sensing contact of the abdomen, the initial pressure value or a derivative thereof can be used as a direct or indirect indication of the tension of the belt.