The invention discloses a high-polymer dust suppressant, belonging to the field of dust suppression. The high-polymer dust suppressant comprises a polymer molecule (C18H29O3S)m-(C3H5)n-(C3H4N)z, wherein m>=10, n>=115, and z>=15; and the polymer molecule has a spacial three-dimensional network structure. The high-polymer dust suppressant can prevent and treat open dust sources, can be widely used in coal / metal / nonmetal mining areas, mineral slag stock grounds, coal / ore powder transportation, mineral earthwork storage unloading areas, building evacuation, under-construction road way sides, thermal power plants, cement plants, steel plants, metallurgic plants, dust workshops, artificial beaches, desertification areas and other locations, has favorable wind erosion resistance and compression strength, can display the dust suppression effect for a long time, avoids environmental pollution caused by flying dust or abundant waste of resources (such as coal powder), and has the characteristic of environment friendliness.