10 results about "Naloxazone" patented technology

Naloxazone is an irreversible μ-opioid receptor antagonist which is selective for the μ₁ receptor subtype. Naloxazone produces very long lasting antagonist effects as it forms a covalent bond to the active site of the mu-opioid receptor, thus making it impossible for the molecule to unbind and blocking the receptor permanently until the receptor is recycled by endocytosis.