A spinal fixation system includes a plurality of anchor screw assemblies, e.g. including anchor screws and clamp assemblies defining rod passages therethrough. A rod is receivable in the rod passages between the anchor screw assemblies, and a spacer is securable on the rod. The rod is preferably serrated over less than about 25% of the peripheral surface thereof, and the clamp assemblies preferably include engagement surfaces that include similarly spaced and oriented serrations. During use, a first anchor screw is screwed into a first vertebra, and a second anchor screw is screwed into a second vertebra adjacent the first vertebra, and clamp assemblies are mounted to each anchor screw. A rod is secured between the anchor screw assemblies, thereby fixing a relative spacing of the first and second vertebrae. A spacer may be crimped onto the exposed portion of the rod between the anchor screw assemblies, the spacer extending between the anchor screw assemblies to prevent the anchor screw assemblies, and, consequently, the first and second vertebrae, from moving towards one another.