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3 results about "Toxicity profile" patented technology

Toxicological profile ( toxicity profile ) An examination, summary, and interpretation of a hazardous substance to determine levels of exposure and associated health effects.

"good"buffer-based cationic lipids

PendingAU2022259686B2Organic chemistryToxicity profile
The present invention provides, among other things, a novel class of cationic lipid compounds (e.g., cationic lipids having a structure according to Formula (I)) for in vivo delivery of therapeutic agents, such as nucleic acids. It is contemplated that these compounds are capable of highly effective in vivo delivery while maintaining a favorable toxicity profile.
Owner:TRANSLATE BIO INC

Compositions and methods for delivery of agents

This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.
Owner:MODERNATX INC