42results about "Oxazine dyes" patented technology

The invention provides a closed-loop reaction continuous production process for producing pigment violet 23, which comprises the following steps: a) adding an NMP (N-Methyl Pyrrolidone) solvent into a 100L reaction kettle, starting and stirring to 30 DEG C, adding a reduzate, and stirring for 30 minutes; b) adding sodium carbonate after the step a), and continuously stirring for 30 minutes; c) slowly adding chloranil, keeping the temperature at 35-40 DEG C, and continuously reacting until the reaction is finished; d) transferring the material in the step c) to closed-loop reaction equipment, and controlling the feeding sequence, mode and complete reaction of each component by utilizing a multi-component reaction optimization technology to ensure the reaction of reactants and reduce the generation e of side reaction to the maximum extent; the adding sequence, the reaction environment, the pressure and the flow speed of reactants are accurately controlled in the reaction process, and the high yield and the high purity of the pigment purple 23 are guaranteed; f) continuously carrying out catalytic oxidation reaction in the closed loop by using a static mixer and a small amount of catalyst combination to obtain a product; by optimizing the continuous production process of the closed-loop reaction of the pigment violet 23, adopting a closed-loop reaction system, and performing continuous production and flow marking monitoring and control, the method disclosed by the invention achieves obvious good effects in a plurality of aspects; the production efficiency is improved, the product quality is guaranteed, the production cost is reduced, the environmental friendliness is improved, and the process stability is enhanced.

The application relates to an electronic device comprising an anode, a cathode, at least one emitting layer between the anode and the cathode, at least one p-doped layer A containing a mono-triarylamine as a host, and at least one layer B containing a mono-triarylamine. The invention further relates to a p-doped mixture comprising a mono-triarylamine of formula (II), (III) or (IV) as a host and an electron acceptor compound as a dopant, and the use of the mixture in an electronic device.

Cosmetic and dermatological compositions, including color changing compositions, are provided which typically include a plurality of synthetic particles having a size in the micrometer or nanometer range. Each synthetic particle typically includes one or more aggregates of a pigment selected from phenoxazone, phenoxazine, and a derivate or precursor thereof, and a stabilizing material which has a refractive index larger than 1.45; the aggregates having a size larger than about 100 nm and the composition being biodegradable and biocompatible.

The present application relates to a kind of phenoxazine type dye intermediates, dye precursor, dye and its preparation method, belong to dye technical field.The phenoxazine type dye of the present application is the dye matrix with the phenoxazine intermediate, grafting cyanuric chloride with genipin double active groups, phenoxazine type dye intermediate has excellent color light stability, and high color strength, color light bright, can be dyed in supercritical fluid to fiber.Through the reaction of the iridoid structure of genipin and the amino group on protein fiber, the trinity of fiber-dye-color is generated in the dyeing process.The phenoxazine type dye does not need to apply to water and other dyeing auxiliaries in the dyeing process, the novel special dyeing method, the green environmental protection of dyeing process, the equipment friendly, has better application prospect in supercritical CO2 dyeing.

The present disclosure provides an aza[3.2.1]bridged ring substituted fluorescent dye and a preparation method and use thereof. According to the fluorescent dye, by adopting an aza[3.2.1]bridged ring as a substituent of the fluorescent dye, not only are the brightness and photostability of the fluorescent dye obviously improved, but also the phenomenon of spectral blue shift caused by irradiation of the dye for a long time is completely avoided. Meanwhile, the water solubility of the fluorescent dye can be effectively improved, and good membrane permeability of the fluorescent dye is maintained. The present disclosure further provides embodiments of functionalized derivatives of the dye in single molecule imaging, confocal imaging and super-resolution imaging of biological samples.

Provided herein are libraries of nerve-specific fluorescent contrast agents of substituted 8-methyl-phenoxazine compounds of Formula (I) with excitation and emission profile comparable to US FDA approved methylene blue (MB) and indocyanine green (ICG), respectively, allowing for real-time intraoperative imaging using clinical-grade surgical systems. Also provided 700 nm lead candidates with substantially improved water-solubility, fully negating the need for formulation development with the added advantage of improved safety profiles for patient use in the clinic as well as decreased overall cost of clinical translation.

The application relates to an electronic device comprising an anode, a cathode, at least one emitting layer between the anode and the cathode, at least one p-doped layer A containing a mono-triarylamine as a host, and at least one layer B containing a mono-triarylamine. The invention further relates to a p-doped mixture comprising a mono-triarylamine of formula (II), (III) or (IV) as a host and an electron acceptor compound as a dopant, and the use of the mixture in an electronic device.

Cosmetic ingredient comprising a photochromic molecule denominated FC-SPOX for cosmetic products changing colour when irradiated through ultraviolet light (UV, preferably UV-A). Formula (I). Method of synthesis of such photochromic molecule. Monosubstituted and disubstituted transesterification product between FC-SPOX and a polymer or cosmetic oil with the aim of increasing the molecular weight of FC-SPOX. Formula (I). Method for the transesterification. Cosmetic compositions for make-up containing said photochromic transesterification product, capable of changing colour both per se and when applied to the skin when they are exposed to UV radiation.

To provide compounds, conjugates and methods that may be used to detect the presence of an analyte in a sample, such as a biological sample.SOLUTION: The invention provides compounds of formula (I), or salts thereof.SELECTED DRAWING: Figure 1

The present invention relates to organic light emitting elements, comprising thermally activated delayed fluorescence (TADF) emitters and / or hosts of formulawhich have a sufficiently small energy gap between S1 and T1 (ΔEST) to enable up-conversion of the triplet exciton from T1 to S1. The organic light emitting elements show high electroluminescent efficiency.

Disclosed herein are compounds, conjugates and methods that can be used to detect the presence of an analyte in a sample, such as a biological sample.

The present invention discloses phenothiazine / phenoxazine-based organic compounds, their preparation methods, and applications. The phenothiazine / phenoxazine-based organic compounds of the present invention have good photophysical properties, high biocompatibility, small molecular weight, large Stokes shift, and excellent targeting performance. They can accurately stain subcellular structures in biological cells and effectively locate them in organelles in a wash-free manner, thereby achieving subcellular structure images with a high signal-to-noise ratio. The phenothiazine / phenoxazine-based organic compounds of the present invention have low cytotoxicity and large Stokes shift as small molecule fluorescent dyes. Compared with commercial organelle dyes, the fluorescent dyes of the present invention can specifically accumulate in cell mitochondria, cell membranes, lysosomes, endoplasmic reticulum, and lipid particles, and have excellent photostability, and can be used to observe the microstructure of cells and cell-to-cell interactions for a long time.

The invention relates to a distorted condensed ring blue vat dye with pyrazine and oxazine structures and a preparation method and application thereof, and discloses a preparation method and application of a blue vat dye with a certain distorted structure. According to the blue dye, different conjugated units are creatively connected in parallel through oxazine and pyrazine fused rings, the conjugated structure of molecules is expanded, the absorption wavelength of the molecules is subjected to red shift, and meanwhile, the fused rings provide high rigidity and stability for the molecules. In addition, the heterocyclic structure of oxazine and pyrazine also provides certain distortion for molecules, so that accumulation among molecules is improved, certain solubility of the molecules is ensured, and intramolecular charge transfer is enhanced. Through the design, the absorption spectrum, the light stability, the heat stability and the acid-base stability of the molecule are improved, and huge potential is provided for the molecule as a novel blue vat dye.

The invention discloses a micromolecular fluorescent dye with emission wavelength exceeding 1300 nm and a preparation method thereof. Complex fluorescent molecules with the emission wavelength exceeding 1300 nm are constructed through nucleophilic substitution, electrophilic substitution, coupling reaction and oxidation reaction, the route steps are short, operation is easy and convenient, the total yield is high, the synthesis difficulty, time and cost are greatly reduced, and the method is suitable for industrial production. Multiple functional group modification and tedious pi-system expansion steps for adjusting the spectral performance in the prior art are avoided, and a traditional synthesis path needing more than six steps is compressed to four steps. The molecular weight of the prepared fluorescent dye is only 592.2383, and the traditional design difficulty that long wavelength is inevitably accompanied by large molecular weight (generally gt and 800 Da) in the prior art is fundamentally broken through.

The invention discloses a dichroic dye, a liquid crystal composition and application of the dichroic dye. The structural general formula of the disclosed dichroism dye compound is shown as I in the specification. The liquid crystal composition comprises the dichroic dye and at least one liquid crystal compound. The dimming glass device prepared from the dichroic dye or the liquid crystal composition has the advantages of high photo-thermal stability, high order parameter and wide working temperature range.

A small molecule ionic isolation lattice (“SMILES”)-doped polymeric gain media for use in solid state dye lasers. The SMILES-doped polymeric gain media can comprise a polymer component and a SMILES component. The SMILES component can include a dye element, a counterion element, and a receptor element. In some exemplary embodiments, the SMILES composite can include the following formula: a (dyem+)x·(counterionn)y·(receptor)z, wherein values of m, n, x and y may be integers greater than or equal to 1.

The invention discloses amino-functionalized Nile blue dye as well as a synthesis method and application thereof, and belongs to the field of organic synthesis. According to the method, by optimizing the catalyst type, the reaction temperature and the solvent system, the generation of isomer byproducts is effectively inhibited, and the reaction selectivity is improved. Compared with the prior art, the synthesis process disclosed by the invention has the advantages of simple reaction steps, mild and controllable conditions, high product yield and high purity; meanwhile, large-scale use of strong acid, strong alkali and expensive noble metal catalysts is avoided, and the production cost is remarkably reduced. The obtained amino-functionalized Nile blue dye has long wavelength absorption, excellent cell membrane permeability and wide pH tolerance range (pH 2-11), and can generate superoxide anion free radicals under red light excitation. Based on the characteristics, the compound can be widely applied to the fields of biological fluorescence labeling and functional material preparation.

The invention discloses a permanent violet nitration production method, which relates to the technical field of chemical substance preparation, and comprises the following steps: uniformly dissolving N-ethyl carbazole in an inert organic solvent to prepare a component A, and injecting the component A into a nitration kettle; taking nitric acid as a component B, and connecting the component B into a reaction liquid pipe of the nitration kettle through a pipeline; mixing the component B with the reaction liquid from the nitration kettle, dispersing the mixture into fine particles through a high-speed dispersion pump, and feeding the fine particles into a tubular reactor; cooling the mixed material through an outer jacket of the tubular reactor, returning the cooled mixed material to the nitration kettle to realize circulation, and continuing stirring reaction; and recovering the material, cooling, standing for layering, discarding upper-layer waste acid, and cooling, crystallizing and filtering a lower-layer solvent layer to obtain a nitration product.

A substrate having an edible color additive within the substrate or coated on the substrate is disclosed. The edible color additive comprises xanthommatin at a concentration of about 0.01% wt to about 0.5% wt and optionally a dry based carrier or a solution-based carrier. The substrate is a food, beverage, drink, medication or a drug form. The color additives of the disclosure can be produced in the color spectrum of yellow, orange, red, or concentrated forms (e.g., concentrated yellow appears as brown).

The invention relates to a display device and an electronic device. The display device may include a display panel, a touch sensing layer, and a reflection adjustment layer. The touch sensing layer may include a touch insulating layer. The touch insulating layer may include a colorant and may cover the first light emitting region. The reflection adjustment layer may be disposed on the touch sensing layer. The reflection adjustment layer may include a first adjustment portion, which is a non-polarizing portion, and a second adjustment portion, which is a polarizing portion. The first adjustment portion may cover the first light emitting region, and the second adjustment portion may cover a second light emitting region. The display panel may be configured to emit light of a first wavelength band through the first light emitting region, and the touch insulating layer may be configured to selectively transmit light of the first wavelength band.

The present invention provides a photoprotective cosmetic composition containing xanthomatin as an antioxidant and a UV filter stabilizer. [Solution] Unsaturated solutions of phenoxazone and / or phenoxazine or their precursors or derivatives, such as xanthomatine, are used in dermatological and skincare formulations as separate molecules to enhance protection and safety. Unaggregated xanthomatine molecules boost UV filtering performance, enhancing the photostability and UV absorption properties of known chemical UV filters. Xanthomatine molecules in unsaturated solutions replace the performance of avobenzone, a UV-A filter in sun care products, and replace the performance of known antioxidants, resulting in higher performance stability over time. Unsaturated solutions of xanthomatine provide safer and more effective broad-spectrum protection.

The present invention discloses an oxy-phenothiazine salt compound, its preparation method, and application. The present invention adopts the "heavy atom-free effect" and utilizes the bridging sulfur atom of the oxygen-substituted phenothiazine salt to perform homologous atom substitution to develop a novel fluorescent dye, an oxy-phenothiazine salt (MBO). The oxy-phenothiazine salt of the present invention reduces the spin-orbit coupling (SOC) constant of methylene blue (MB) and the intersystem crossing rate (k) from the singlet state to the triplet state. ISC ), enhancing its fluorescence imaging capabilities and offering improved safety and lower cytotoxicity compared to methylene blue itself. The novel fluorescent dye of the present invention combines blue staining of lymph nodes with fluorescence imaging, making it suitable for use in the preparation of reagents for sentinel lymph node biopsy, intraoperative lymph node tracing, and clearance.

The present disclosure relates to a compound represented by Chemical Formula 1, a probe for detecting antibiotic-resistant bacteria, which includes the compound, a composition containing the compound, a kit including the compound and a method for detecting antibiotic-resistant bacteria. A compound probe having a carbapenem structure and including a linker and a fluorophore can detect beta-lactamase or carbapenemase at high sensitivity and, therefore, can be applied to various biochemical researches. In addition, the compound probe can clinically detect carbapenemase-producing antibiotic-resistant bacteria and allows molecular diagnosis of antibiotic-resistant bacterial infectious diseases and analysis of antibiotic-resistant bacteria from a target sample at high sensitivity. Therefore, it can be effectively used for medicinal uses such as in-vitro diagnosis.

The application relates to an electronic device comprising an anode, a cathode, at least one emitting layer between the anode and the cathode, at least one p-doped layer A containing a mono-triarylamine as a host, and at least one layer B containing a mono-triarylamine. The invention further relates to a p-doped mixture comprising a mono-triarylamine of formula (II), (III) or (IV) as a host and an electron acceptor compound as a dopant, and the use of the mixture in an electronic device.

The invention discloses a near-infrared nile blue fluorescent dye and a synthesis method and application thereof, and the dye has excellent fluorescence intensity and is suitable for near-infrared region fluorescence imaging. A series of novel fluorescent dyes NRO-N are successfully prepared by replacing diethylamino of Nile blue with various tertiary amine structures, introducing alkyl groups or sulfonyl groups with different lengths at different positions of molecules, replacing anions with different anions and adjusting the luminous intensity and solubility of the Nile blue dye. Wherein the fluorescence intensity of NBO-2-ClO4 in a phosphoric acid buffer solution is higher than that of a contrast molecule diethylamino Nile blue. A new tool is provided for the fluorescent dye for near-infrared region imaging, the preparation process is simple and efficient, large-scale production is easy, and the fluorescent dye has wide clinical application prospects.

A composition of tin-doped titanium dioxide (Sn—TiO2) particles, a redox-active dye that changes color from exposure to ultraviolet (UV) light, visible light, or a combination thereof, and a paint matrix, along with methods of making the composition and uses of the composition are described herein. Compositions of TiO2 particles, wherein the TiO2 particles are at least 80% anatase or at least 80% rutile, in combination with a redox-active dye that changes color from exposure to ultraviolet (UV) light, visible light, or a combination thereof, and a paint matrix are also described herein.

The present disclosure provides coinage metal carbene emitters of Formula I; organic light emitting device (OLED) comprising an anode, a cathode, and an organic layer, disposed between the anode and the cathode, comprising a compound of Formula I; and consumer products comprising an OLED comprising a compound of Formula I:

The present disclosure concerns the design, formulations, preparations and optical properties of compounds of Formulas (I) and (VI):(charged dyem+)x·(counterionn−)y·(counterion receptor)z  (I) and(charged dyem−)x·(counterionn+)y·(counterion receptor)z  (VI).The charged dyem+ is a cationic dye, counterionn− is an anion, and counterion receptor is a binding ligand for the counterionn−, wherein m, n, x and y are integers greater than or equal to 1, and products of x·n and m·y are identical for formula (I).The charged dyem− is a anionic dye, counterionn+ is a cation, and counterion receptor is a binding ligand for the counterionn+, wherein m, n, x and y are integers greater than or equal to 1, and products of x·n and m·y are identical for formula (VI).

The invention discloses a dichroic dye, a liquid crystal composition and application of the dichroic dye. The structural general formula of the disclosed dichroic dye compound is shown as I, and the disclosed liquid crystal composition comprises the dichroic dye and at least one liquid crystal compound. The dimming glass device prepared from the liquid crystal composition related to the dichroism dye has the advantages of high light and heat stability, high order parameter and wide working temperature area.