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92results about How to "Achieve long-term effect" patented technology

In situ gel preparation loaded with Kangfuxin and its preparation method and use

The invention belongs to the field of medicinal preparations and a novel medical technology and relates to an in situ gel preparation loaded with Kangfuxin and its preparation method and use. The in situ gel preparation loaded with Kangfuxin has temperature sensibility. The in situ gel preparation loaded with Kangfuxin is characterized in that Kangfuxin as a raw material and polymers are dissolved in a buffer solution or purified water according to a ratio. Because of polymer reverse-phase gel properties, the in situ gel preparation loaded with Kangfuxin is in a liquid state and can freely flow at a room temperature (of 20 DEG C) under storage conditions, and when the in situ gel preparation loaded with Kangfuxin is spread on a wound, under the action of a body temperature, the in situ gel preparation loaded with Kangfuxin forms fast semi-solid gel. The in situ gel preparation loaded with Kangfuxin is convenient for patient use, improves patient compliance, can effectively store drugs and can slowly release drugs so that drug action time is prolonged and drug efficacy is improved. Through oral administration, the in situ gel preparation loaded with Kangfuxin can be used for treating blood stasis, stomachache, gastrorrhagia, gastric ulcer and duodenal ulcer and assistantly treating Yin deficiency and pulmonary tuberculosis, and phthisis. Through external administration, the in situ gel preparation loaded with Kangfuxin can be used for treatment and anti-adhesion of metal-inflicted wounds, trauma wounds, ulcer wounds, fistula wounds, burn wounds, scald wounds, bedsore wounds and surgical wounds.
Owner:王成

Rice hull carbon-based microbial fertilizer and preparation method and application thereof

The invention relates to a microbial fertilizer and a preparation method and application thereof, in particular to a rice hull carbon-based microbial fertilizer and a preparation method and application thereof, and aims at solving the problems that after an existing microbial fertilizer is applied, due to the low microbial content, the poor microbial activity and the weak microbial competitiveness, the yield of crops is low. The rice hull carbon-based microbial fertilizer is prepared from 50-70% of rice hull charcoal, 9-11% of beneficial microorganism complex microbial inoculant, 9-11% of binder and the balance nutrient elements. The preparation method includes the steps of 1, processing of the rice hull charcoal; 2, preprocessing of the nutritive elements; 3, fungicide compounding; 4, preparation of the rice hull carbon-based microbial fertilizer. According to the application, the rice hull carbon-based microbial fertilizer is added into chemical fertilizer according to the additive amount of 3%-5% by mass for being used. The rice hull carbon-based microbial fertilizer provides a perfect habitat for probiotics, crop growth can be stimulated, metabolism of the crops can be adjusted, the yield is increased obviously, the fertilizer efficiency is durable, and the per mu yield of the crops is increased by 8%-23%. The preparation method and application are suitable for the rice hull carbon-based microbial fertilizer.
Owner:黑龙江省农业科学院农村能源研究所

Method for preventing and controlling freeze-expanded damage to water-containing subgrade in cold region and bunched low-temperature heat pipe

The invention discloses a method for preventing and controlling freeze-expanded damage to water-containing subgrade in a cold region and a bunched low-temperature heat pipe. The method is characterized in that a T-shaped bunched solar low-temperature heat pipe capable of transmitting solar energy or electric energy heat into the subgrade is arranged in the subgrade; when the environmental temperature is lower than 0 DEG C, a working medium on the evaporation segment of the low-temperature heat pipe absorbs solar energy heat and rises to be conducted into the condensation segment of the low-temperature heat pipe; on cloudy days, the working medium on the evaporation segment is heated through electric heating, and is conducted into the condensation segment of the low-temperature heat pipe; heat is transmitted into the water-containing subgrade through the condensation segment in order that the temperature of the water-containing subgrade is greater than the icing temperature; the working medium which releases heat returns back into the evaporation segment under the action of gravity to absorb heat, and the abovementioned work is performed circularly in order that the temperature of the water-containing subgrade is kept higher than the icing temperature, so that the occurrence of freeze-expanded damage to the subgrade is prevented. The method is simple and reliable, the phenomenon of frost heaving of the subgrade can be effectively avoided, and the transportation safety is ensured.
Owner:江苏中圣压力容器装备制造有限公司

K237 polypeptide-modified invisible nanoparticles and application thereof

InactiveCN101822641AAchieve targeted anti-tumor therapyOvercome the disadvantage of relatively narrow applicationPowder deliveryMacromolecular non-active ingredientsPolyethylene glycolTumor therapy
The invention relates to K237 polypeptide-modified invisible nanoparticles, which consist of K237 polypeptide and invisible nanoparticles. The invisible nanoparticles are made of polyethylene glycol-polylactic acid amphiphilic copolymer with end blocking aldehyde group. The invention also provides application of the K237 polypeptide-modified invisible nanoparticles and application of the polyethylene glycol-polylactic acid amphiphilic copolymer with the end blocking aldehyde group. In the invention, the K237 serving as targeted head groups is modified on the surfaces of the invisible nanoparticles; and after intravenous administration, the medicament-carried invisible nanoparticles actively target the carried medicament to the endothelial cells of the tumor vessel through the K237-VEGF02-mediated active targeting action so as to realize targeted anti-tumor therapy of the tumor vessel. The K237 polypeptide-modified invisible nanoparticles overcome the defects of poor targeting in cationic liposome and narrow application range that the RGD or CRGDC serving as the targeting head group can only target to the tumor vessel with integrin expressed to be positive.
Owner:SHANGHAI JIAOTONG UNIV SCHOOL OF MEDICINE

Preparation process for quartz stone with long-acting organic antibacterial performance

InactiveCN107892504AImprove compatibilityInhibit volatilization and exudationChemistryAdhesive
The invention provides a preparation process for quartz stone with long-acting organic antibacterial performance. The preparation process comprises the following steps: (1) weighing components according to a formula; (2) heating unsaturated polyester resin to 30 to 50 DEG C, adding a coupling agent and an organic antibacterial agent, and carrying out high-speed stirring for polymerization so as toform an prefabricated solution of organic polymer antibacterial resin; (3) adding a curing agent and a pigment and filler, carrying out mixing, adding the obtained mixture into a beater and carryingout grinding so as to form an organic polymer antibacterial adhesive; (4) dumping quartz powder, quartz sand and modified organic silicon resin into a hopper, carrying out stirring at a low speed andthen adding the organic polymer antibacterial adhesive so as to form a prefabricated material of quartz stone; and (5) subjecting the prefabricated material of quartz stone to tiling, compaction and curing so as to obtain the quartz stone with long-acting organic antibacterial performance. The preparation process for the quartz stone with long-acting organic antibacterial performance employs a manner of prefabrication of the organic polymer antibacterial adhesive to give better play to the antibacterial performance of the organic antibacterial agent, so the prepared quartz stone has more obvious and long-acting organic antibacterial performance. The preparation process is simple and convenient.
Owner:FOSHAN YIXIN STONE CO LTD

Environment-friendly and sound-insulation building paint and preparation method thereof

The invention discloses environment-friendly and sound-insulation building paint and a preparation method thereof. The environment-friendly and sound-insulation building paint is prepared from the following raw materials in parts by weight: 25 to 35 parts of quartz sand, 20 to 30 parts of aqueous silicone acrylic emulsion, 18 to 25 parts of lightweight calcium carbonate, 10 to 15 parts of lignosulfonates, 15 to 20 parts of diatomite, 10 to 15 parts of sodium polycarboxylate, 15 to 25 parts of montmorillonite clay, 2 to 4 parts of organic silicon modified epoxy resin, 5 to 8 parts of nanometer aluminum silicate and 6 to 9 parts of talcum powder. The environment-friendly and sound-insulation building paint has a good sound-adsorption effect and is safe and environmentally friendly; the indoor space is saved; a coating has a good sound-adsorption effect and the coating has no seams and is stuck with a wall body to form a whole body, so that an indoor space is hardly occupied; meanwhile, the environment-friendly and sound-insulation building paint disclosed by the invention also has the effects of purifying air and adjusting the humidity; a coating film contains a plurality of pores and the inner area is large; toxic and harmful gas in the air can be adsorbed; and meanwhile, the humidity of the indoor air can be adjusted, and a pore wall, especially wood fibers, can adsorb certain moisture when the air humidity is relatively great.
Owner:芜湖浩权建筑工程有限公司

Composite improved planting soil for vegetation restoration of mining slopes and preparation of composite improved planting soil

The invention discloses a preparation method of composite improved planting soil for vegetation restoration of mining slopes. The preparation method comprises following steps: (1), grinding distillers' grains, bagasse, diatomite and fly ash, and performing sieving to obtain a prefabricated material a; (2), thickening and dewatering municipal sludge, carrying out drying and smashing, adding iron tailing sand to be mixed uniformly, adjusting water content, then adding a binding agent, conducting granulation, feeding particles into a rotary kiln, carbonizing the particles at 500-600 DEG C for 20-30 min, performing cooling, and adding activated carbon and decomposed organic fertilizer to be mixed uniformly to obtain a prefabricated material b; and (3), uniformly mixing the prefabricated material a and the prefabricated material b, adding a fermented liquid to the mixture for decomposing at the decomposing temperature of 40-50 DEG C for 20-40 days, keeping the water content of the mixture at 16wt%-20wt% in the decomposing process, drying the mixture, adding polymaleic anhydride and polyvinyl alcohol to be mixed uniformly, and conducting granulation to obtain the composite improved planting soil for vegetation restoration of the mining slopes.
Owner:广西七色草科技有限公司

Nano-silver microsphere emulsion, and preparation method and applications thereof

InactiveCN103911853ANon-irritatingProtect against moistureFibre treatmentMicrosphereAntibacterial activity
The invention discloses an emulsion containing nano-silver solid microspheres, and a preparation method and applications thereof. According to the preparation method, PluronicF-127 is taken as a reducing agent and a dispersant for loading of nano-silver ions; and PluronicF-127 microspheres loaded with nano-silver ions are protected with paraffin via fusion spraying; and at last, combination with dopamine is realized so as to obtain the antibacterial finishing emulsion used for woven fabric or knitted fabric. Advantages and effects of the emulsion are that: (1) PluronicF-127 is an amphipathic chain-segment polymer, is capable of forming micelles in water, and can be used as the reducing agent and the dispersant of nano-silver; (2) solid paraffin is taken as a hydrophobic protective agent, and can be used for protecting nano-silver frozen powder from water so as to prolong antibacterial activity preservation period; (3) the emulsion possesses excellent dip coating performance, and can be used for antibiotic finish of woven fabric or knitted fabric as a functional finishing agent, and more than 98% of antibacterial activity can be maintained after 200 times of soaping; and (4) the emulsion containing nano-silver solid microspheres is capable of resisting oxidation, acid, alkali, light, and water.
Owner:GUANGDONG VOCATIONAL & TECHNICAL COLLEGE
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