This invention discloses a method for preparing a self-healing hydrogel with both sensing and antibacterial properties. The invention uses a hydrogel prepared from
acrylamide (AM) and 2-(methacryloyloxy)ethyl dimethyl-(3-sulfopropyl)
ammonium hydroxide (SBMA) and
cellulose nanofibers (CNF) as a matrix, silver-coated polydopamine nanoparticles (Ag@PDA NPs) as antibacterial and conductive agents, and 2-hydroxy-4'-(2-hydroxyethoxy)-2-methylphenylacetone (I2959) and
polyethylene glycol diacrylate (PEGDA) as photoinitiators and crosslinking agents. A multifunctional hydrogel with multiple dynamic reversible bonds is prepared by
ultraviolet light-initiated self-
polymerization. By constructing various dynamic reversible interactions, including covalent and non-covalent bonds and interionic interactions, a self-healing Ag@PDA NPs / AM / SBMA / CNF hydrogel was obtained. Ag and DA were introduced to prepare Ag@PDA with antibacterial,
adhesive, and
electronic conductivity properties, while zwitterionic SBMA was introduced to provide
ionic conductivity. The synergistic effect of these two compounds endows the hydrogel with electrical
conductivity. The hydrogel dressing prepared by this method can achieve rapid sterilization while possessing excellent
biocompatibility,
high adhesion,
high conductivity sensing ability, and environmental adaptability.