32results about How to "Prevent and reduce injury" patented technology

Embodiments of the present disclosure include a user detection system for exercise equipment, such as a treadmill. In an embodiment, a sensor monitors displacement between a deck supporting a moveable treadmill belt and aspects of a treadmill frame. As users interact with the treadmill, a processor uses a sensor signal indicative of the displacement to determine whether a user has mounted the treadmill belt.

The present invention provides methods of reducing the cytotoxic effects of nitric oxide and sulfides comprising coadministering nitric oxide with sulfide. In addition, the present invention provides novel pharmaceutical compositions comprising both nitric oxide and sulfide. The methods and compositions of the present invention may be used in the treatment or prevention of a variety of diseases and disorders, and also in the prevention of cell or tissue damage, including that resulting from ischemi hypoxia.

A fall arrest system for a billboard is disclosed. The billboard may have horizontally extending ribs and vertically extending sprits. A first bracket and a second bracket, each having a horizontal portion and a vertical portion, are provided. The horizontal portion extends beyond the billboard. The vertical portion has channels for receiving the ribs therein. At least one mechanical fastener connects the brackets to the ribs. An arresting line extends from the first bracket to the second bracket.

The present invention provides methods for conferring cytoprotection and treating, suppressing or reducing the incidence of ischemia. The methods make use of an ester or amide of an alpha-ketoalkanoic acid, such as ethyl pyruvate, or compositions comprising the same.

The invention is related to methods of protecting, preventing and reducing intestinal injury in a human subject suffering from or at risk for shock, hemorrhagic shock or hemorrhagic shock and resuscitation (HS/R) comprising administering heparin binding epidermal growth factor (HB-EGF). The invention is also related to methods of inhibiting deterioration of intestinal blood flow and methods of preserving and increasing intestinal blood flow by administering HB-EGF to a human subject. In addition, the methods of the invention should improve the clinical outcome of human subject suffering from or at risk for shock, hemorrhagic shock or hemorrhagic shock and resuscitation.

A vehicular head and neck safety system for use by an occupant of a vehicle comprising a net sized to contain the occupant's head while the occupant is seated in a seat of a vehicle, wherein the net is secured behind a headrest of the seat using fasteners. During a rapid deceleration event, such as a frontal collision, the system limits the forward movement and downward rotation of the occupant's head to prevent or reduce injury.

Provided herein are methods for prevention and treatment of ischemia-reperfusion (IR) injury in the cardiac myocytes of a subject, by administration to the subject, a compound of formula I, or a salt, solvate, or stereoisomer thereof, in a sufficient amount either prior to, or during and/or after an ischemic event to mitigate or prevent IR injury to the cardiac tissue. Pharmaceutical compositions including the compound of formula I, or a salt, solvate, or stereoisomer thereof, and/or at least one additional therapeutic agent, are also provided.

This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.

The invention provides a vibrator assembly of a centering structure, which comprises a flat plate assembly and a heavy hammer assembly, a hammer body of the heavy hammer assembly is connected with the flat plate assembly through an elastic connecting piece, and the two ends of a piston rod of the heavy hammer assembly are fixedly connected with the flat plate assembly through end covers; the elastic connecting piece comprises a centering spring, a centering spring seat and a centering spring seat limiting seat, a centering spring mounting hole is formed in the hammer body, and the centering spring is in close fit with the centering spring mounting hole of the hammer body through tolerance fit. Due to the closed box type structural design, the vibrator assembly has high torsion resistance and sufficient rigidity, the overall performance of the vibrator assembly is more stable, meanwhile, space is saved, the length and width of the whole vehicle are greatly reduced, and the vibrator assembly is beneficial to exploration in cities and towns. The mechanical structure is more stable and firmer, and compared with an air bag, the wear resistance is longer, and the service life is longer.

Neuroinflammation mediated by microglia and infiltrating peripheral immune cells is a major component of stroke pathophysiology. The calcium activated potassium channel K_Ca3.1 is expressed selectively in the injured CNS by microglia, and K_Ca3.1 function has been implicated in proinflammatory activation of microglia. K_Ca3.1 is further implicated in the pathophysiology of ischemia/reperfusion (stroke) related brain injury. Senicapoc, an investigational drug with a proven safety profile and shown to cross the blood-brain barrier, is a potent and selective K_Ca3.1 inhibitor that intervenes in the inflammation cascade that follows ischemia/reperfusion, and is a potential treatment for stroke.

This invention relates to privacy screens, specifically, portable privacy screens with an integrated vertical height measuring tool. A portable lightweight privacy screen that can be conveniently carried and assembled and disassembled. The privacy module has one ruled segmented crown and one ruled segmented base which are identical and interchangeable with each other. They are each considered a single unit that is detachably connected together by a plurality of tubular couplers and bungee cord. The privacy module also has a plurality of ruled segmented supporting poles which are identical and interchangeable with each other. Each is considered a single unit that is detachably connected together by a plurality of tubular couplers and bungee cord. The present invention provides the collapsibility aspect by attaching bungee cord at two points on each of the separate units, giving the user the quick ease of assembling and disassembling of the structure. Further intent of the present invention is to increase the privacy area for the user, by providing a plurality of walls. The design of the present invention to provide privacy on a plurality of sides is also facilitated by an easily detachable fabric cover, interlaced with elastic from end to end, on top and bottom, which attaches and secures the fabric cover at a plurality of points by an elastic loop on the ends of the ruled segmented crown and ruled segmented base. The present invention also provides the option of attaching a plurality of privacy module together. The present invention also presents an integrated means of measuring a person's standing height by adding graduating marks to the segmented supporting poles, as well as to the segmented crown and the segmented base. Height indicator marks are placed on top of the ruled segmented crown in conjunction with the ruled segmented supporting poles, to align them with the vertically placed ruled auxiliary arm, for height extensions above 6-feet.