Embodiments of the present invention provide a method and apparatus for determining an interdental relationship. The method comprises: acquiring a three-dimensional tooth digital model of a patient from at least one orthodontic stage or collected from the patient; determining, according to the three-dimensional tooth digital model, tooth feature information of at least one tooth, the tooth feature information being used for representing a spatial feature of the tooth; determining, according to tooth feature information of a first tooth, a
reference line of the first tooth and an auxiliary line corresponding to the
reference line, the
reference line and the auxiliary line forming at least one division region, and the first tooth being one tooth in the three-dimensional digital model; and determining, according to the reference line and the auxiliary line corresponding to the reference line, a corresponding
tooth surface region located in the same division region from the tooth feature information, the
tooth surface region being configured to determine an interdental relationship between the first tooth and other teeth. By means of more accurately determining the reference line and the auxiliary line, the corresponding
tooth surface region is determined from the tooth feature information, thereby facilitating subsequent accurate determination of the interdental relationship according to the tooth surface region.