The invention provides a self-positioning clamping lathe. The self-positioning clamping lathe comprises a lathe body, a rotating spindle, an automatic supplementing device, an automatic feeding deviceand a clamp rotating device; the automatic feeding device comprises a feeding driving assembly, a cutting assembly, a self-centering assembly and a cutting control assembly; the clamp rotating devicecomprises a clamping assembly and a clamping control assembly; when the automatic feeding device moves towards the rotating spindle, workpieces falling from the automatic supplementing device at intervals are transported into the clamp rotating device, make contact with the clamp rotating device and then are self-centered, in the process that the automatic feeding device continues moving forwards, the workpieces are automatically clamped through the clamping assembly, meanwhile, the distance between the cutting assembly and the workpieces is controlled through the cutting control assembly, thus automatic feeding, positioning, clamping and machining integration of workpieces are achieved, and the technical problems that in the prior art, the coaxiality between the workpieces and the rotating spindle is difficultly ensured during clamping, the machining error is large during machining, and the precision is low are solved.