The invention discloses a radiation low-pressure environment simulation cabin, which comprises a protection frame and a simulation cabin. The inner side of the protection frame and the outer side of the simulation cabin are fixedly installed, and the simulation cabin comprises a heat preservation cabin body, a low-pressure cabin body, a ventilation hole plate, a circulating fan, a heating unit, a refrigerating unit, an evaporator, a vacuum unit and a temperature sensor. According to the radiation low-pressure environment simulation cabin, the refrigerating unit, the heating unit and the circulating fan are started to send the adjusted temperature to the position above the ventilation hole plate in the heat preservation cabin body through the air pipe, then the adjusted temperature is evenly sent into the heat preservation cabin body through the ventilation hole plate, and the adjusted air evenly radiates the six wall faces of the low-pressure cabin body under the flowing condition; the purpose of controlling and adjusting the temperature in the low-pressure cabin body is achieved, air in the heat preservation cabin body returns to the temperature adjusting section through the air pipe, circulation in the heat preservation cabin body is formed, meanwhile, the circularly flowing air can be dehumidified and dried at the position where the air passes through the evaporator, and dew condensation on the wall face of the low-pressure cabin body is further avoided.