54results about How to "Avoid variability" patented technology

The invention relates to methods for culturing human embryonic stem cells by culturing the stem cells in an environment essentially free of mammalian fetal serum and in a stem cell culture medium including amino acids, vitamins, salts, minerals, transferring, insulin, albumin, and a fibroblast growth factor that is supplied from a source other than just a feeder layer the medium. Also disclosed are compositions capable of supporting the culture and proliferation of human embryonic stem cells without the need for feeder cells or for exposure of the medium to feeder cells.

A method of acquiring at least one clinical MRI image of a subject comprising the following steps: acquiring a first survey image with a first field of view, the first survey image having a first spatial resolution,—locating a first region of interest and at least one anatomical landmarks in the first survey image, determining the position and the orientation of the first region of interest using the anatomical landmarks, the position and the orientation of the first region being used for—planning a second survey image,—acquiring the second survey image with a second field of view, the second survey image having a second spatial resolution, the second spatial resolution being higher than the first spatial resolution, generating a geometry planning for the anatomical region of interest using the second survey image,—acquiring a diagnostic image of the anatomical region of interest using the geometry planning.

Disclosed herein are compositions and methods for the treatment of otic disorders with otic structure modulating compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).

Disclosed herein are compositions and methods for the treatment of otic disorders with immunomodulating agent compositions and formulations administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).

Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with free-radical modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).

The invention discloses an evaluating system of depressive disorder degree quantization. The system comprises an electrocardio and pulse wave integral detection device, a data transmission device and a data processing platform. The invention further discloses an evaluating method of depressive disorder degree quantization. The method comprises the following steps that firstly, human physiological information under different states is acquired through a multi-state comprehensive test platform; secondly; HRV characteristic parameters under the different states are obtained on the basis of the heart rate variability analysis principle; thirdly, the function balance states of sympathetic nerves and pneumogastric nerves in the automatic nervous system are evaluated; fourthly, a depressive disorder degree quantization evaluation model is built, and the depressive disorder degree level of a tested person is evaluated fast and objectively. The system and method belong to the technical field of computer-aided diagnosis, depressive disorder degree quantization evaluation is achieved, the blank of the technical field of depressive disorder inspection is filled up, and the system and method are easy and convenient to implement, save medical resources and have the good clinic practicality.

A metal-insulator-metal capacitor is embedded in an interconnect layer of an integrated circuit (IC). The interconnect layer has a cavity, and the capacitor is formed in the cavity with one of the plates of the capacitor integral with a conductive layer of the interconnect layer, so the capacitor plate electrically communicates with the interconnect layer. The interconnect layer has multiple conductive layers, including a layer, such as aluminum, that is subject to deformation at certain temperatures during fabrication of the IC, and the cavity extends through this layer. A remaining conductive layer of the interconnect layer defines one of the capacitor plates, and a dielectric layer and another capacitor plate are formed thereon within the cavity. Via interconnects of about the same length electrically connect to the top plate and through the interconnect layer to the bottom plate.

A fastener driving tool includes a power source including a reciprocating driver blade, a tool nose associated with the power source for receiving the driver blade for driving fasteners fed into the nose, a magazine constructed and arranged to house a supply of the fasteners, a magazine feeder mechanism associated with the magazine for sequentially feeding fasteners into the nose, the feeder mechanism including, operating between a retracted position and an advanced position and an electromechanical retention device that is operationally associated with the feeder mechanism and configured for retaining the mechanism in the retracted position until the driver blade is positioned to allow fastener advancement into the nose.

The invention discloses an airspace staggered wave position arranging method for a phased array radar. The airspace staggered wave position arranging method for the phased array radar includes steps that 1) selecting a scanning airspace under a correction ball coordinate system; 2) converting the scanning airspace under the correction ball coordinate system into a sine airspace under a sine space coordinate system through coordinates; 3) confirming the line space and column space between adjacent wave positions under the sine coordinate system; 4) confirming the wave position arrangement of the whole sine region to generate a wave position table; 5) removing the wave positions outside the airspace range set by a user to form the staggered wave position arrangement of the scanning airspace. The airspace staggered wave position arranging method for the phased array radar uses the sine coordinate system to carry out wave position arrangement on the whole airspace based on covering the required airspace, avoids the change of the wave beam shape along with the wave beam directing, realizes the uniform arrangement of the wave position under the sine coordinate system, guarantees that the 3 dB coverage rate arrives at 90% while the overlapping ratio is 0, and has broad application prospect.

A combined type single stud illuminating building block includes a circuit board, an illuminating member and an outer housing. The circuit board includes a top side and a bottom side opposite to each other. The circuit board is extended to form at least one first connection portion. The bottom side includes an electrode circuit. The illuminating member is mounted on the top side and electrically connected with the electrode circuit. The outer housing includes a connection hole to receive the circuit board and the illuminating member. The outer housing is hollow and light transmittable. The outer housing includes at least one second connection portion connected with the at least one first connection portion, respectively. Thus, the combined type single stud illuminating building block can be connected with the building block having various numbers of engaging studs to enhance degrees of freedom and variability of connection.

Systems and methods for providing protection from failure events in a digital audio amplification system. One embodiment of the invention comprises a system having a digital amplifier controller, an amplifier output stage coupled to the controller and configured to receive audio signals from the controller, one or more sensors coupled to the output stage and one or more low-pass filters coupled to receive sensor signals from the one or more sensors. The low-pass filter is configured to filter the sensor signals and to provide the filtered sensor signals to the controller, which provides a programmable response to the filtered sensor signals. The response may range from not taking any action, to limiting the amplification of audio signals, to shutting down the system.

The invention discloses a preparation method of a ZIF-8/Au compound surface enhanced Raman substrate. The method comprises the steps that nano gold is prepared; the nano gold with the particle diameter of 40-60 nm is selected to dissolved in 5 ml of deionized water to form a nano gold aqueous solution for later use; 1.17 g of Zn(NO3)2-6H2O is dissolved in 7 g of deionized water, 1 ml of the nano gold aqueous solution is added; 22.70 g of 2-methylimidazole is dissolved in 80 g of deionized water; a 2-methylimidazole solution is stirred and mixed with a Zn(NO3)2-6H2O and nano gold mixed solution, stirring is conducted for 5 minutes, and precipitants are collected after centrifugation; the precipitants are repeatedly flushed by using the deionized water for two times, and powder shape ZIF-8/Au compound surface enhanced Raman substrate is obtained after drying. The ZIF-8/Au compound surface enhanced Raman substrate has the advantages that the clearance between the nano gold particle is ensured, the variability of nano particle aggregation is avoided, and therefore stronger spectral enhancement effect in measuring is achieved.

The present invention provides a method of predicting the mutual affinity of two molecules for each other in solution, by computing the configuration integrals of the free molecules and their bound complex as sums over local energy wells. The invention makes accurate calculations computationally tractable for a range of molecular systems by several means, including restraining the conformations of selected molecular components, and using a single conformation representative of an energy well to correct an efficient but less accurate energy model toward a slower but more accurate model.

Provided is a ruthenium alloy sputtering target as a ruthenium alloy sintered compact target obtained by sintering mixed powder of ruthenium powder and metal powder capable of creating oxides easier than ruthenium, wherein purity of the target excluding gas components is 99.95 wt % or higher, said target contains 5 at % to 60 at % of metal capable of creating oxides easier than ruthenium, relative density is 99% or higher, and oxygen content as impurities is 1000 ppm or less. This ruthenium alloy sputtering target is capable of reducing its oxygen content, reducing the generation of arcing and particles during sputtering, increasing the target strength by improving the sintered density, and improving the deposition quality by strictly restricting the amount of B and P impurities in the target in order to prevent the compositional variability of B and P added in minute amounts to the Si semiconductor.

Stresses or deformations can be applied to a specimen, by at least one carrier having a number of flexible fingers extending therefrom, the fingers being securable to the specimen at spaced-apart locations, the carrier typically being attached to a motion-control and load measuring system. The fingers are relatively rigid in tension (or compression if desired) but flexible with respect to motions in other in-plane directions. They may or may not be flexible in out-of-plane directions. Commonly, there may be two carriers on opposite sides of the specimen for applying substantially uniaxial stress, or four carriers at 90 degrees to each other around the specimen for applying substantially biaxial stress, though any number of carriers may be used.

Extrusion dies for manufacturing substrates with peripheral strengthening are manufactured by plunge EDM machining a solid material and subsequently forming slots by wire EDM slot machining.

A closed-system urinary catheter with a low viscosity gel lubrication is disclosed. The system has an uncoated catheter, but a hydrophilic coated catheter could be used. The low viscosity lubricating gel within the sachet uniformly coats the catheter when the sachet is ruptured just prior to use. A low viscosity lubrication gel could alternatively be place in the area inside the sheath and external to the catheter. Therefore, the variability that occurs with a hydrophilic catheter or the areas of a non-lubricated catheter with the higher viscosity gel catheters is avoided.

The invention relates to nesting bi-characteristics fast problem locating and information self filtering general systematic method. It diagnoses and locates various abnormal problems in system running by systematic building one set of context environment description behavior and information self synthesizing mechanism which can greatly save locating problem required time and various resources demand, is convenient for various personnel to adopt proper matching measure to treat the problem. The invention uses multilayer characteristic sign, nesting type synthesizing mechanism, and general assemble output service mechanism to finish no recurrence fast locating problem and system diagnosis.