The invention relates to thermosetting plastic and its preparation method and a power lithium battery pack assembly casing prepared from the thermosetting plastic. The thermosetting plastic comprises a base, fillers, a reinforcing material and aids. The base is prepared from thermosetting resins such as unsaturated polyester resin and vinyl ester resin. The fillers are inorganic non-metallic fillers such as wollastonite and barite. The preparation method comprises (1), dispersion, (2) stirring mixing, kneading and dipping, and (3) curing molding. The assembly casing comprises two or more single boxes connected with each other. The single box forms an integral structure through injection molding. The boxes are provided with connection holes or connection tabs connected to a vehicle frame. The main characteristics of the thermosetting plastic comprise that 1, a thermal deformation temperature is more than 250 DEG C higher than that of the reaction temperature of the lithium compound, 2, the thermosetting plastic is flame retardant, resists a high temperature and does not collapse after burning, 3, the spark discharge caused by battery short circuit is effective resisted, 4, insulation and thermal conductivity are obtained and a battery design is convenient, and 5, weight is light, electrombile weight reduction is promoted and noise is reduced.