The invention discloses a framework association-based pipe support-suspension frame model reconfiguration method. The method comprises the steps of 1, performing pre-configuration on a pipe support-suspension frame framework model: adopting design type software, designing each part involved in the pipe support-suspension frame framework model into templates to form a technological design template generic library; in the pre-configuration of the pipe support-suspension frame framework model, calling single/multiple pipe support-suspension frame frameworks from the technological design template generic library firstly, selecting the direction of a support, selecting a reference plane according to number of supporting legs, then selecting single pipes, defining single pipe references in the pipe support-suspension frame framework, and determining whether the support is a multi-pipe support or not; and 2, performing reconfiguration of the pipe support-suspension frame model. By adoption of the reconfiguration method, the functions of multi-modal representation, intelligent reconfiguration, automatic selecting, environment adaptive configuration and the like of the pipe support-suspension frame model are realized, so that the design and configuration efficiency and the design quality of the support-suspension frame in three-dimensional design of a pipeline system are greatly improved.