62results about "Testing/calibration for volume metering" patented technology

This present disclosure provides reliable methods and apparatus for delivering microdroplets containing an active pharmaceutical ingredient (API) to underlying substrates. A control system is provided to ensure that the API dosage is both accurate and repeatable.

A method for ascertaining at least one configuration of a metering device for buik goods to be metered. A method for obtaining a recommendation for a configuration of a metering device for buik goods to be metered, and devices for processing data are also provided.

Method for monitoring a state in a device (1) for metering and / or transferring material (53), wherein the device (1) has a stationary housing (3) with an inlet side (4) for supplying the material (53) and an outlet side (5) for dispensing metered quantities of the material (53), and a metering unit (7) with a metering chamber (12), and the method comprises the following steps: i) transferring the metering chamber (12) into a state temporarily closed with respect to the inlet side (4) and the outlet side (5), wherein the metering chamber (12) is bounded by at least one wall element (11) of the metering unit (7); ii) introducing a fluid, in particular a gas, into the metering chamber (12) in the closed state by means of a pressure generation unit (16) in order to increase the pressure (P) in the metering chamber (12); iii) Measuring the pressure (P) in the dosing chamber (12) with a pressure measuring unit (17);and iv) Determining the state of the device based on the measured pressure (P), in particular based on a pressure profile (27a, 27b).;

A system configured to determine the presence of an anomaly associated with a dispensing system component, a fluid supply, and / or a tool of a dispenser includes: a fluid supply for containing a fluid; the tool is used for supporting the part; one or more sensors configured to sense a characteristic of the dispensing system component, fluid supply, and / or tool; and a controller configured to actuate the one or more sensors to capture initial data associated with the dispensing system component, fluid supply, and / or tool at a first time, processing the initial data in a trained neural network to determine the presence of anomalies associated with the dispensing system components, fluid supplies and / or tools, recording the presence of anomalies, generating and sending an alert indicative of the presence of anomalies to a human-machine interface, the one or more sensors are actuated to capture subsequent data associated with the dispensing system component, fluid supply, and / or tool at a second time after the first time, and the subsequent data are processed to determine whether the anomaly has been corrected.

Method (100) for classifying coatings (230) in a measuring tube (200), comprising: determining (110) a damping value D for at least one vibration mode of an oscillator with at least one measuring tube (200) of a Coriolis mass flow sensor for guiding a medium (220); determining (120) a modal stiffness value k for at least one vibration mode; and classifying (150) the coating (230) as a function of the damping value D and the stiffness value k.

A metering bank for an air cart. The metering bank includes metering bank frame and a plurality of meter modules disposed laterally adjacent to one another in the metering bank frame. Each of the plurality of meter modules is independently removable from the metering bank in a direction generally parallel with the forward direction of travel of the air cart. Each of the plurality of meter module includes a metering mechanism.

Microdosing system (100, 300) for dosing a quantity of fluid to be dispensed, comprising: a micropump (101) having an inlet (102) and an outlet (103) and designed to draw in the fluid (104, 105, 109) to be discharged through the inlet (102) and to discharge at least part of the fluid (104, 105, 109) from the outlet (103), a first flow sensor (106a, 106b) arranged on the inlet or outlet side, which has an opening (107a, 107b) and a flow meter (108a, 108b), wherein the flow meter (108a, 108b) is configured to determine the flow rate of the fluid (104, 105) passing through this opening (107a, 107b), and means (113, 313) for calibrating and / or interfering detection of the microdosing system (100, 300), wherein the means (113, 313) for calibrating and / or detecting disturbances of the microdosing system (100, 300) comprise a control device (302) configured to detect an actual sensor signal of the first flow sensor (106a, 106b) when the micropump (101) is inactive, and to correct subsequent sensor signals of the first flow sensor (106a, 106b) based on this in order to counteract sensor drift of the first flow sensor (106a, 106b) and to calibrate the microdosing system (100, 300).

An air cart having a modular metering system. The modular metering system includes a plurality of meter modules disposed laterally adjacent to one another in a metering bank. Each of the meter modules is independently removable from the metering bank. Each meter module includes a metering mechanism rotatable about a longitudinal axis disposed generally parallel with a forward direction of travel of the air cart. The metering mechanism is in communication with a supply of product held within a tank. As the metering mechanisms rotates about its longitudinal axis, the product is metered by the metering mechanism into an air tube associated with each of the plurality of meter modules. An air stream provided by at least one fan carries the metered product through the air tubes.

A method and apparatus for measuring the volume of liquid contained in a syringe having a barrel) with a barrel flange and a barrel bottom surface and plunger with a plunger flange. An image of the syringe is captured and processed to determine a length dimension of the syringe that is characteristic of its model. The length dimension determined from the image processing is used to look up the syringe model in a dataset that stores the relevant length dimension for each syringe model. The dataset also stores, for each syringe model, calibration values representing the volume of liquid contained in the syringe at each of at least two plunger positions. The volume of liquid held in the syringe can be determined from the plunger position obtained by processing the image, more specifically from the distance between the barrel flange or barrel bottom surface and plunger flange.

A method is for producing individual dosing quantities of a powdered product via a drum dosing device. A dosing drum has a dosing opening on its circumference. In an ejection position, an ejection process is effected, the dosing opening being subjected to a positive pressure and the dosing quantity being thereby ejected from the opening, and an associated ejection reference time-point being determined. The individual mass of an ejected dosing quantity and an associated measurement reference time-point are determined via the measuring device. An actual time period is ascertained from the difference between the measurement reference time-point and the ejection reference time-point and compared with a specified time period. In dependence on the comparison, an adaptation of the positive pressure for a subsequent ejection process is performed such that the level of the positive pressure is increased if the actual time period is too great.

The invention relates to a method for ascertaining at least one configuration of a metering device for bulk goods to be metered, to a method for obtaining a recommendation for a configuration of a metering device for bulk goods to be metered, and to devices for processing data.

An example container for collecting bulk material dispensed from a meter during a calibration operation may include a canister comprising an open end to receive bulk material, a coupler configured to releasably couple to a meter, and at least one weight sensor extending between the enclosure and the coupler. The weight sensor may be configured to detect weight of the bulk material deposited into the enclosure via the open end.

The measuring tube module (M1) comprises a tube (11) with a lumen (11*) enclosed by a wall and extending from a first (tube) end to a second (tube) end, first and second measuring electrodes (21, 22) positioned on and / or in the wall of the tube for tapping electrical potentials established within a measuring substance located in the lumen of the tube, at least one electrical coil (31) mechanically connected to the tube for generating and / or detecting a magnetic field (H), and coil electrodes (311, 312) positioned on and / or in the wall of the tube and electrically connected to the coil. The measuring tube module can also be a component of a modular system or be used to form a modular (flow) measuring device suitable for measuring at least one measured quantity of an (electrically conductive) liquid substance flowing in a process line and / or a test arrangement for a basic module (M2) of the modular system (M1, M2).

A procedure for verifying a pipette, wherein the result of verification is a release or warning message, the procedure comprising the following steps: providing a liquid measuring container for receiving the liquid volume of the pipette to be verified; a weighing sensor connected to the liquid measuring container in a force-transmitting manner, the weighing sensor outputting a measurement signal corresponding to the gravity acting on the weighing sensor; and a processing unit for detecting and processing the measurement signal of the weighing sensor; determining a first gravity at a time point from the stable measurement signal, and determining a second gravity at a time point; calculating the liquid volume of the pipette; assigning the calculated liquid volume of the pipette to one of at least one pipette volume class having a defined nominal value; having the processing unit test whether the absolute value of the volume difference is within the tolerance value of the nominal value of the assigned pipette volume class; and having the processing unit output the test result.

Assembly (1) comprising a distributor (2) for distributing pressurised fluid and a simulator (3) of a tank to be filled from the distributor (2), the simulator (3) comprising a transfer line connected to the distributor (2) and comprising a pressure controller (PCV1), the pressure controller (PCV1) being configured to regulate a pressure and / or a flow rate of a fluid flow passing through the pressure controller (PCV1), so as to simulate a pressure rise in the tank to be filled, the distributor (2) and the simulator (3) respectively comprising a main flow meter (FEO) and a secondary flow meter (FE2), the main flow meter (FEO) being configured to estimate a first quantity of a fluid flow supplied to the pressure controller (PCV1) and therefore to the tank simulated by the pressure controller (PCV1), the secondary flow meter (FE2) being arranged on the transfer line, downstream of the pressure controller (PCV1), and configured to measure a second quantity of the fluid flow supplied to the pressure controller (PCV1) and therefore to the tank simulated by the pressure controller (PCV1), characterized in that the simulator (3) also comprises a programmable electronic control member (PEC) configured to compare the second quantity of the fluid flow with the first quantity of the fluid flow, so as to verify the reliability of the first quantity of the fluid flow.

The invention is achieved by a volumetric displacement calibration device (1) configured to be able to adapt at least one suction system (1000), comprising a tip (1006), having a volume VP, connected to a shaft (1003) comprising a volume change mechanism (1002). The device (1) comprises at least one main chamber (10) and one reference chamber (20), connected by a conduct (100) and a valve (102) to said main chamber (10) and at least one first pressure sensor (12) connected to said main chamber (10). The device (1) comprises also a second pressure sensor (22) connected to said reference chamber (20). The pressure sensors and calculation means allow to calculate an internal volume Vo, being the sum of the volume VP of said aspiration tip (1006), the volume (1005) of the shaft (1003) when the volume change mechanism (1002) is down. The invention is also achieved by a system (2) comprising the device (1) and at least one suction system (10001- 1000n) adapted to said device (1). The invention relates also to a calibration method of a volumetric fluid handling system (2) and comprising successive steps (a-m) to determine said volume Vo.

A system for determining the presence of fluid or air in a transparent tube in a drug preparation device is provided. [Solution] The system includes a processing circuit (PC) configured to receive a camera image of the transparent tube, where the transparent tube is positioned in front of a patterned background from the camera's perspective, whereby one or more regions of the transparent tube are depicted in the received image, each depicted region being associated with a respective refractive index of the patterned background; identify one or more of the regions of the transparent tube in the received image using image processing techniques; and determine characteristics of the contents of the transparent tube from at least one or more of the identified regions.

In a method for selecting a metering device (1) and determining operating parameters for metering a bulk material (2) with unknown flow properties using said metering device (1), an optical image of a specified quantity of the bulk material (2) is recorded in a reference environment (4). Geometric parameters of the bulk material (2) are determined on the basis of the optical image. A user is guided by a dialogue with an input module of an electronic data processing device. A characteristic variable for the flow properties of the bulk material (2) is determined using a machine learning method and on the basis of the determined geometric parameters and the responses of the user. The user inputs a desired conveying rate for the bulk material (2) via the input module and receives a suggestion for a suitable metering device (1) and for suitable operating parameters for metering the bulk material (2), the operating parameters being based on the determined characteristic variable for the flow properties and the desired conveying rate.

A method for calibrating a filling system is disclosed. In a first calibration step, a calibration of a calibration variable of a first flow or level measuring device is performed at a first calibration point. In a first deviation determination step, the first control and evaluation unit of the measuring device determines an average deviation of the calibration variable from a desired value. In a first correction step, the first control and evaluation unit corrects a calibration parameter taking into account the determined deviation. In a first transmission step, the first control and evaluation unit transmits the determined deviation and / or the corrected calibration parameter to the second control and evaluation unit. In a first adaptation step, the second control and evaluation unit corrects a calibration parameter at a first calibration point, taking into account the deviation transmitted by the first control and evaluation unit or the transmitted calibration parameter.

A method and apparatus for measuring the volume of liquid contained in a syringe having a barrel with a barrel flange and a barrel bottom surface and plunger with a plunger flange. An image of the syringe is captured and processed to determine a length dimension of the syringe that is characteristic of its model. The length dimension determined from the image processing is used to look up the syringe model in a dataset that stores the relevant length dimension for each syringe model. The dataset also stores, for each syringe model, calibration values representing the volume of liquid contained in the syringe at each of at least two plunger positions. The volume of liquid held in the syringe is determined from the plunger position obtained by processing the image to determine the distance between the barrel flange or barrel bottom surface and plunger flange and the calibration values.

The invention relates to a method for testing spray jets (10, 12) for a component of a sprayer, comprising the following method steps: positioning the component to be tested in a receiving unit of a testing device and connecting the component to a liquid reservoir; clamping the component to be tested and at this time drawing a determined volume of test fluid from the liquid reservoir; operating the component to be tested so as to produce a spray jet (10, 12); the spray jets (10, 12) darken the light band or beam of the grating; measuring the darkening of the light strip or beam by means of a sensor unit and recording and evaluating the measured values (14) in a time-dependent manner; a start (t3) of the spray jet (10) and / or an end (t4) of the spray jet (12) and / or a duration (24) of the spray jet (10, 12) are / is calculated on the basis of the obtained measurements (14).

This application relates to a flow measurement method, apparatus, computer equipment, storage medium, and computer program product. The method includes: when the error of the flow measurement result exceeds the allowable error range, adjusting the flow measurement pipeline to a first state where it is filled with liquid and the liquid is stationary; performing zero-point calibration on the flow measurement parameters based on the first state to obtain zero-point calibration parameters, so that the flow velocity measurement result obtained based on the zero-point calibration parameters in the first state is zero; adjusting the flow pipeline to a second state where it is filled with liquid and the liquid is flowing, and obtaining the instantaneous flow velocity measurement result in the second state; obtaining the full-scale coefficient in the flow measurement parameters, and obtaining a corrected full-scale coefficient based on the instantaneous flow velocity measurement result and the cumulative flow of the liquid during the sampling period; and measuring the flow rate of the liquid in the pipeline based on the corrected full-scale coefficient and the zero-point calibration parameters to obtain the measurement result. This method can achieve accurate measurement of the flow rate of fluid in a pipeline.

Provided herein is a compact and integrated spray device testing system that significantly reduces user error and testing operating time. In some embodiments, the spray testing system may use automation and an integrated mechanical design for actuating and weighing the spray device to improve data collection accuracy and reduce testing time.

SOLUTION: A gas delivery system for a substrate processing system includes a gas box including mass flow controllers controlling a flow of gas from gas sources. A gas flow path is in fluid communication with the gas box. A hybrid flow measurement system is in fluid communication with the gas flow path, and includes a controller configured to perform first flow measurement. The first flow measurement is for calibrating at least one of the mass flow controllers on the basis of a differential mass of gas in the gas flow path between the gas box and the flow measurement system during a predetermined period when a desired flow rate for gas supplied by the at least one of the mass flow controllers is less than a predetermined flow rate. The controller is configured to perform second flow measurement when the desired flow rate is greater than the predetermined flow rate.SELECTED DRAWING: Figure 3

Calibration of a droplet dispenser includes providing a liquid sample including a calibrant and, for each liquid level of a range of different liquid levels providing the liquid sample to a set of wells at the liquid level. Further, over a range of different droplet dispenser parameters, the droplet dispenser is used to dispense droplets from the set of wells into a flowing transport fluid. A mass of calibrant ions generated from the flowing transport fluid is measured using a mass spectrometer. Volumes of the droplets from are determined from the calibrant mass.

A method (1) for operating a filling device (2) with a filling valve (3) for controlling a medium flow, with a time-discrete sampling flow sensor (4) for measuring the medium flow (V') released by the filling valve (3) and with a control unit (5) for controlling the filling valve (3) is presented and described, wherein the control unit (5) controls the filling valve (3) to carry out a filling process with a defined target filling quantity (Vtarget) taking into account the measured actual filling quantity (Vist), which is determined using the flow measurement values ​​recorded by the flow sensor (4).A measurement error caused by the time-discrete sampling of the flow measurement is reduced by synchronizing (sync) the start of the filling process between the filling valve (3) and the flow sensor (4), so that the first sampled (tsl) flow measurement value of the flow sensor (4) is in a defined temporal relationship to the initial opening (topen) of the filling valve (3) during the filling process.

Automatic syringe quality control systems, apparatus and methods are provided. The automatic syringe quality control systems, apparatus and methods may determine a plunger depth within a syringe that has been pre-filled with a medication. The plunger depth may be based on digital image data.

The invention relates to a measurement tube module (M1) comprising: a tube (11) having a lumen (11*) that is enclosed by a wall and extends from a first (tube) end to a second (tube) end; first and second measurement electrodes (21, 22) positioned on and / or in the wall of the tube for tapping electrical potentials established within a measuring medium located in the lumen of the tube; at least one electrical coil (31) mechanically connected to the tube for generating and / or detecting a magnetic field (H); and coil electrodes (311, 312) that are positioned on and / or in the wall of the tube and are electrically connected to the coil. The measurement tube module may also be a component of a module system or be used to form a modular (through-flow) measuring device used to measure at least one measurement variable of an (electrically conductive) liquid measuring medium flowing in a process line, and / or a test arrangement for a base module (M2) of the modular system (M1, M2).

In a method for measuring the volume of dispensed liquid droplets, the aim is to provide a method that is convenient, quick, and easy to use even with small amounts of liquid. [Solution] A method for determining the volume of a liquid droplet dispensed from a liquid dispensing device, comprising the steps of: (a) depositing a liquid of an assumed volume measured on a calibration reference surface from the liquid dispensing device as a droplet, the calibration reference surface providing a known contact angle with the droplet under the deposition conditions used; (b) establishing a known angle with the droplet selected from the group consisting of an advancing contact angle, a receding contact angle, and an intermediate contact angle; (c) measuring the dimensions of the droplet, the measured dimensions being selected from the group consisting of the maximum height of the droplet, the diameter of the contact patch, the radius of curvature, and the cross-sectional area; and (d) calculating the actual volume of the droplet from the relationship between the measured dimensions and the known contact angle, wherein the advancing contact angle, receding contact angle, and intermediate contact angle are established by changing the kinetic energy given to the deposited droplet.

A method (100) for calibrating a filling plant (1) is presented and described, in which, in a first calibration step (101), a calibration of a calibration parameter of the first flow or level measuring device (4) is carried out under process conditions at a first calibration point, in a first deviation determination step (102), the first control and evaluation unit (5) of the first flow or level measuring device (4) determines an average deviation of the calibration parameter measured by the first flow or level measuring device (4) from a target value of this calibration parameter at the first calibration point, and in a first correction step (103), the first control and evaluation unit (5) corrects at least one calibration parameter taking into account the determined deviation.In a first transmission step (104), the first control and evaluation unit (5) transmits the determined deviation in the first calibration point and / or the at least one corrected calibration parameter via the communication channel (8) to the second control and evaluation unit (7), and in a first adjustment step (105), the second control and evaluation unit (7) corrects at least one calibration parameter in a first calibration point, taking into account the deviation or calibration parameter transmitted by the first control and evaluation unit (5).