63 results about "Capillary inlet" patented technology

A method for introducing ions generated in a region of relatively high pressure into a region of relatively low pressure by providing at least two electrospray ion sources, providing at least two capillary inlets configured to direct ions generated by the electrospray sources into and through each of the capillary inlets, providing at least two sets of primary elements having apertures, each set of elements having a receiving end and an emitting end, the primary sets of elements configured to receive a ions from the capillary inlets at the receiving ends, and providing a secondary set of elements having apertures having a receiving end and an emitting end, the secondary set of elements configured to receive said ions from the emitting end of the primary sets of elements and emit said ions from said emitting end of the secondary set of elements. The method may further include the step of providing at least one jet disturber positioned within at least one of the sets of primary elements, providing a voltage, such as a dc voltage, in the jet disturber, thereby adjusting the transmission of ions through at least one of the sets of primary elements.

A method and apparatus are provided for identifying analytes at low concentrations in a liquid sample. The liquid sample is introduced through a continuous flow membrane inlet system. The analytes that permeate the membrane are analyzed by photoionization-time-of-flight mass spectrometry. The analytes remaining in the liquid sample that do not permeate the membrane are conducted to a capillary tube inlet that introduces the liquid sample and other analytes as droplets into the photoionization zone. Any analytes remaining absorbed or adsorbed on the membrane are driven through the membrane by application of heat. Analytes may be analyzed by either resonance enhanced multiphoton ionization (REMPI) or single photon ionization (SPI), both of which are provided in the apparatus and can be selected as alternative sources.

The compressor compresses gas in capillaries leading to a radially distant annular container space. Centrifugal force acts on gas bubbles entrained between liquid slugs moving radially outward through the capillaries which may be radial, tangential or continuously curved. Compressed gas is collected in the annular space. A gas-liquid emulsion is fed to the capillaries by an inboard emulsification device. The emulsification may include a vortex generator, an ejector or a venturi injector, all feeding the gas-liquid mixture into the inboard ends of the capillaries. The capillaries are formed in a series of discs, coaxially stacked with outer disc ends open to the annular space. Capillary inlets may be perpendicular, tangential or may define a venturi jet.

The present invention relates to a capillary microcuvette, the microcuvette comprises a body member having two plates and a cavity formed within the body, the cavity being defined by two opposing inner surfaces of the two plates of the body member, a portion of the cavity defining a detection zone, a capillary inlet being provided at one end of the body member that is communicated with the cavity, a sample slot being provided at a portion of the body member in which the capillary inlet is not formed, the sample slot being communicated with the cavity. The present microcuvette improves user convenience by providing dual application means of applying a specimen directly from a fingertip or using a pipette.

A measurement device containing one or more capillaries to measure the volume of a dispensed fluid and determine the volumetric accuracy of the dispensing device. The measurement device can contain a reservoir containing the fluid to be measured and there may be an additional reservoir for a secondary fluid. A viewing window is necessary to complete a manual measurement and may include a magnifying lens. The liquid well by the capillary inlet may be shaped such that the measurement fluid is directed toward the capillary. The well may have features designed to position the dispensing device toward the capillary, or to position the well proximal to the capillary after it is filled. The well may also have surfaces or coatings which attract or do not attract various types of substances. The measurement device may interface with sensors to output measurement data.

The invention provides a high-throughput nucleic acid continual amplification apparatus and a method, and belongs to the technical field of biochemical apparatuses. The amplification method comprises the following steps: enabling a PCR reaction material to flow along a capillary tube, regulating the temperature of the reaction material by multiple temperature control areas arranged at the exterior of the capillary tube, and successively performing denaturation, annealing, extending on the PCR reaction material to finish the PCR amplification reaction. The amplification apparatus comprises three temperature control areas arranged in order, the temperature control areas are connected end to end and form an closed structure, the capillary tube is arranged in the temperature control areas and twines around the closed structure of the temperature control areas, the inlet of the capillary tube is arranged above the temperature control area for executing the denaturation reaction, the outlet of the capillary tube is arranged above the temperature control area for executing the extending reaction, and the inlet of the capillary tube is connected with a conveying device. The PCR amplification method and the apparatus help to realize continual amplification on a large batch of reaction systems, and help to realize simultaneous amplification and detection on multiple reaction systems or multiple samples.

A microfluidic device includes a substrate, first and second capillary inlets, a microfluidic channel unit, an outlet disposed downstream of the microfluidic channel unit, and a suction member disposed downstream of the outlet. A first liquid is drawn into a first sub-channel and a main channel of the microfluidic channel unit through the first capillary inlet. A second liquid is drawn into a second sub-channel of the microfluidic channel unit through the second capillary inlet. The suction member provides a predetermined suction force to permit the second liquid to penetrate into the first liquid and to break up into droplets in the first liquid, thereby generating monodisperse emulsions.

The invention discloses a hydrothermal large-cavity high-temperature high-pressure experimental device and an experimental method. The device comprises a kettle body and a kettle plug, wherein the kettle body is a hexagonal structure and has a sample empty cavity structure in the kettle body; six detachably-sealed kettle plugs are respectively connected to six sides; optical windows are arranged on three horizontally-arranged kettle plugs; a three-electrode sensor is mounted on the remaining horizontally-arranged kettle plug; a thermocouple is arranged on the kettle plug at the upper end of the kettle body; a high-pressure capillary inlet is formed in the kettle plug at the lower end of the kettle body; a heating device is arranged outside the kettle body; and an optical detection device is arranged at the position facing the optical window. The device adopts a detachable kettle plug structure, does not need to manufacture high-pressure kettles with different sizes, only needs to manufacture kettle plugs with different lengths, can control the thickness of a solution in the sample cavity according to the different lengths of the kettle plugs, and effectively solves the technical problem that the thickness of the solution cannot be changed in the prior art.

The invention relates to a parallel circulation system with hot gas defrosting and cooling capacity recovery for a two-temperature refrigerator. A compressor outlet is divided into two ways connectedwith a condenser inlet and a three-way valve inlet; a condenser, a drying filter and a three-way valve are connected sequentially; two outlets of the three-way valve are connected with a refrigeratingchamber capillary inlet and a freezing chamber capillary inlet; a refrigerating chamber capillary outlet is connected with a refrigerating chamber evaporator inlet; a refrigerating chamber evaporatoroutlet is connected with a pipeline of a three-way valve outlet so as to be connected with a compressor inlet; a freezing chamber capillary is provided with two paths of outlets; one path is connected with a freezing chamber evaporator inlet and a one-way valve inlet; a one-way valve outlet is connected with a pipeline between the three-way valve outlet and the refrigerating chamber capillary inlet; the other path is connected with the freezing chamber evaporator inlet; a freezing chamber evaporator outlet is connected with one connector of the three-way valve; and the other connector of thethree-way valve is connected with the refrigerating chamber evaporator outlet so as to be connected with a compressor air suction port. According to the parallel circulation system with hot gas defrosting and cooling capacity recovery for the two-temperature refrigerator provided by the invention, the defrosting efficiency of a freezing chamber is improved, and meanwhile, a cooling performance thefreezing energy efficiency of a cooling system are further improved remarkably.

The invention relates to capillary tube chromatographic columns, particularly to a preparing method of high-flux parallel capillary tube chromatographic columns, which is quick and convenient. The to-be-filled particulate filler is added into acetone to be prepared into homogenate; a porous silicon sphere with the particle size greater than the inner diameter of the capillary tube is pressed into one end of the capillary tube, and a single-particle silicon sphere is pushed into the capillary tube to serve as an outlet plunger piston; the inlet end of the capillary tube is communicated with a reservoir, the homogenate is added into the reservoir and placed on a centrifuge to be centrifuged, and a stationary phase enters a capillary tube column as driven by gravity and centrifugal force; the other single-particle silicon sphere is pressed into the inlet end of the filled capillary tube column to serve as an inlet plunger piston; and the prepared capillary tube column is stored for further use.

The invention discloses a low-noise low-energy-consumption refrigerating system and a working method thereof. The refrigerating system comprises a compressor, wherein an outlet of the compressor is connected with an inlet of a condenser; an outlet of the condenser is connected with an inlet of a drying filter; an outlet of the drying filter is connected with an inlet section of a capillary tube; an outlet section of the capillary tube is connected with an inlet tube of an evaporator; the inlet tube of the evaporator is connected with the evaporator; the evaporator is connected with an outlet tube of the evaporator; the outlet tube of the evaporator is connected with an inlet of a low-pressure liquid storage device; an outlet of the low-pressure liquid storage device is connected with an inlet of an air return tube; the outer wall surface of the capillary tube between the inlet section of the capillary tube and the outlet section of the capillary tube is sequentially attached to the outer wall surfaces of the outlet tube of the evaporator, the low-pressure liquid storage device and the air return tube; and an outlet of the air return tube is connected with the compressor. Accordingto the low-noise low-energy-consumption refrigerating system and the working method thereof, a multi-section heat return mode is utilized, so that the dryness of a refrigerant at the outlet of the capillary tube is reduced, and the energy consumption of the system is reduced while the noise of the refrigerating system is reduced.

The invention relates to a capillary inlet flow regulator. The capillary inlet flow regulator is characterized by comprising a cylindrical water outlet base, a water inlet cover, a core seat and a disk-shaped elastic membrane, wherein a round hole is arranged on the sidewall of the water outlet base, a cylindrical joint pipeline is arranged on the circumference of the round hole, the water inlet cover is arranged on the top portion of the cylindrical joint pipeline, a water inlet communicated with the cylindrical joint pipeline is arranged on the cover plate, the core seat is arranged in the cylindrical joint pipeline and comprises a round bottom plate, a cylindrical retaining wall is arranged on the top portion of the round bottom plate, a water inlet ring is formed between the periphery of the cylindrical retaining wall and the cylindrical joint pipeline, a central water outlet is arranged at the center of the round bottom plate, a plurality of fan rings protruding upwards are arranged at intervals on the circumference of the central water outlet, surfaces of the fan rings are arc-shaped, groove runners are formed between every two adjacent fan rings, a central jacking column protruding upwards is arranged in the central water outlet, detachable adjusting plates are respectively arranged at positions, corresponding to the groove runners, on the cylindrical retaining wall, and the disk-shaped elastic membrane is arranged in the cylindrical retaining wall and above the fan rings and the central jacking column.

A freeze-thaw valve and a method of micro-machining the freeze-thaw valve is provided and includes a valve housing, wherein the valve housing defines a housing cavity and includes a housing inlet, a housing vent, a capillary tubing inlet and a capillary tubing outlet. A valve body is provided, at least a portion of which is lithographically constructed, wherein the valve body includes a refrigerant inlet, a refrigerant outlet and an expansion chamber. The expansion chamber is disposed to communicate the refrigerant inlet with the refrigerant outlet and includes a restriction region having a flow restriction. Additionally, the valve body is disposed within the housing cavity to form an insulating channel between the valve housing and the valve body.

An IMS detector has a pin-hole or capillary inlet (4, 104, 204) having a coating (42, 242) of a material, such as polydimethylsiloxane, which is adsorbent to an analyte substance of interest. The analyte is adsorbed into the material (42, 242) until a heater (43) is energised to heat the material and release the adsorbed analyte substance for detection.

The invention discloses a preparing device and method for a nanofiller capillary chromatography microcolumn, and relates to preparation of nanofiller capillary chromatography microcolumns. The preparing device for the nanofiller capillary chromatography microcolumn is provided with a centrifugal machine and a centrifugal filling device. The centrifugal filling device is provided with a detachable PEEK joint, a PEEK interface, a PTFE sleeve, a capillary tube and a centrifugal tube. The method comprises the steps of taking nano particles to be dispersed into acetone, controlling the concentration to be 1 microgram/microliter to 50 micrograms/microliter, evenly mixing the homogenized solution, then conducting oscillation to obtain a homogenate, cutting out a segment of the elastic quartz capillary tube, pressing one single through hole silicon ball with the particle size slightly larger than the inner diameter of the capillary tube into one end of the capillary tube to be used as an outlet plunger, fixing the capillary tube with the outlet plunger into the centrifugal filling device, filling a liquid storage tank with the homogenate, conducting weighting and centrifuging, conducing fixed-phase filling, taking off the filled capillary tube after centrifuging is completed, filling the inlet end of the capillary tube with one through hole silica gel particle used as an inlet plunger, and obtaining the nanofiller capillary chromatography microcolumn.

An apparatus useful for the rapid collection of blood from a subject (e.g., the vein of a bovine subject) and dispensing the blood therefrom into a collection device includes: (a) a capillary body having a capillary chamber formed therein, with the chamber having an inlet and outlet, and with said chamber configured to draw blood therein through the inlet by capillary action; (b) a hollow barrel connected to the chamber outlet; (c) a plunger positioned in the barrel; and (d) a hollow needle connected to the capillary body, with the hollow needle in fluid communication with the capillary chamber through the capillary inlet, so that blood can be rapidly drawn into the capillary chamber through the needle by the combined action of vein pressure (or other pressure, if present, such as arterial pressure) and capillary action.

The invention discloses a ternary-cycle quick-cooling frost-free refrigerator. The refrigerator comprises a box body and a refrigeration system; an exhaust port of a variable-frequency compressor is connected with a first refrigerant pipeline, and a press chamber condenser, a condensation prevention pipe, a left side condenser and a right side condenser are arranged on the first refrigerant pipeline in series connection mode in the flow direction of refrigerant; the refrigeration system comprises a one-inlet-three-outlet electromagnetic valve, a refrigerating refrigeration mechanism, a variable-temperature refrigeration mechanism and a freezing refrigeration mechanism, wherein the one-inlet-three-outlet electromagnetic valve is provided with a branch control first inlet, a branch control second outlet and a branch control third outlet; a refrigerating capillary inlet, a variable-temperature capillary inlet and a freezing capillary inlet are connected with the branch control first outlet, the branch control second outlet and the branch control third outlet respectively; and an outlet of a freezing evaporator is connected with an air suction port of the variable-frequency compressorthrough a second refrigerant pipeline. The invention further discloses a corresponding continuous operation method. According to the refrigerator and the method, the taint of odor between compartmentscan be avoided, opening and stopping control can be independently carried out on any compartment of the refrigerator, the energy waste is avoided, and two different evaporation temperatures are provided for each compartment, so that quick cooling is realized.

The invention discloses a large-cavity high-temperature high-pressure gas-liquid two-phase flow experimental device and an experimental method thereof. The large-cavity high-temperature high-pressuregas-liquid two-phase flow experimental device comprises a kettle body and kettle plugs, wherein the kettle body has a hexagonal structure, and the kettle body is provided with an internal cavity structure for sample placement; six sides of the kettle body are connected respectively with six kettle plugs in a detachable seal way; the three horizontally arranged kettle plugs are provided with optical windows, and the remaining three kettle plugs are provided with a three-electrode sensor, a pH sensor, an Eh sensor or an oxidation sensor; the kettle plug at the upper end of the kettle body is provided with a high-pressure capillary outlet, the kettle plug at the lower end of the kettle body is provided with a high-pressure capillary inlet, and the remaining kettle plug which is horizontally arranged is further provided with a thermocouple; a heating device is arranged outside the kettle body; an optical detection device is arranged opposite to the optical window; the high-pressure capillary inlet is connected to a high-pressure liquid pressurizing device. According to the large-cavity high-temperature high-pressure gas-liquid two-phase flow experimental device, the thickness of the solution in the sample cavity can be controlled according to different lengths of the kettle plugs, thereby solving the technical problem that the thickness of the solution cannot be changed in the prior art effectively.