The invention discloses a medical disposable self-destructing syringe. The medical disposable self-destructing syringe comprises a syringe, a syringe seat, a puncture needle, a protective sleeve, a push rod, a rubber plug and a pressing plate, wherein the syringe has a handle at one end and a needle seat at the other end. the inner side of the syringe is provided with a boss, the boss is integrally formed with the syringe, the push rod is arranged on one side of the boss, a push plate is arranged at one end of the push rod, a ball head is arranged at the other end, the rubber plug is arrangedon one side of the push rod, the rubber plug is closely matched with the inner wall of the syringe, the rubber plug has a spherical groove matched with the ball head on one side, the push rod is movably connected with the rubber plug through the ball head, a connecting rod is provided on one side of the rubber plug, and a plurality of cards arranged in an umbrella shape are fixed on the outer sideof the connecting rod; the puncture needle is arranged on the outer side of the syringe seat, and a protective sleeve is arranged on the outer side of the puncture needle. After the syringe is used,the rubber plug is locked in the inside of the syringe and cannot be pulled out, and then cannot be used again, the infection caused by the secondary utilization of the syringe can be avoided, and thesafety of the injection is ensured.