The invention provides a preparation technology of Zhenwu decoction granules, and relates to the technical field of
traditional Chinese medicine, and the preparation technology comprises the following steps: S1, preparing raw materials: poria cocos, radix paeoniae alba, ginger, bighead atractylodes
rhizome and
radix aconiti carmichaeli; s2, condensation
reflux extraction is adopted, water is added into the prepared raw materials for common
reflux decoction extraction for 1-3 times, the water adding amount is 6-8 times of that of the prepared raw materials each time, extraction lasts for 0.5-2 hours each time, and the temperature is reduced to 60-70 DEG C; s3, merging the filtrates, concentrating under reduced pressure to obtain an extract with the
relative density of 1.10-1.15 (50 DEG C), and performing
spray drying to obtain dry extract
powder; s4, mixing an
excipient with the dry paste
powder, and pressing the mixture into granules in a dry granulator; in the extraction process, condensation
reflux extraction is adopted, it is ensured that volatile components are reserved in an extracting solution, the extracting solution is rapidly cooled to 60-70 DEG C after extraction is finished, the temperature is controlled to be 60-70 DEG C in the closed storage and vacuum concentration process, and the volatile components and thermosensitive components are reserved to the maximum extent.