The invention relates to the technical field of bed sheet production and manufacturing, in particular to an automatic folding device for disposable bed sheet production. The automatic folding device for disposable bed sheet production comprises a bottom plate, a supporting frame, an unwinding unit, a limiting unit, a laser cutting unit, a pressing unit, a folding unit and an adsorption moving unit. The automatic folding device for disposable bed sheet production provided by the invention solves the problems that in the existing bed sheet folding process, due to the fact that a bed sheet is made of a flexible material, the surface of the bed sheet is prone to wrinkling due to the lack of appropriate limiting in the folding process, and the folding effect of the bed sheet is affected; and the bed sheet is made of the flexible material, so that the surface of the bed sheet is usually clamped by a clamp to pull the bed sheet in the process of pulling the bed sheet, the surface of the bed sheet is easily damaged, and the later use effect of the bed sheet is influenced. According to the automatic folding device for disposable bed sheet production provided by the invention, the folding effect of the disposable bed sheet is improved, and the surface of the bed sheet is always kept in a flat state in the folding process of the bed sheet.