A test system based on multiple instances of reconfigurable instrument IP specifically matched to the device under test may be used in integrating automated testing of semiconductor devices between pre-silicon simulation, post-silicon validation, and production test phases, in one embodiment of software and hardware across all three phases, for different devices. The reconfigurable test system comprises: a tester instrument, instances of instrument IP instantiated in the tester instruments, a computer system, and a test program. The tester instrument connects to a device under test (DUT), and includes FPGAs reconfigurable for the three testing phases. The computer system has a user interface, and a controller connected to the reconfigurable tester instrument via a data bus. The test program stored on the controller, and the controller, instantiates interfaces and protocols, and certain process transactions to support the protocols, into FPGAs, to match device interfaces for each DUT, to execute test sequences.