A clock data recovery and a serial-parallel conversion circuit based on over sampling for the receiver of a high speed serial transceiver comprise PLL module, a data space over sampling module, an edge detection and data recovery module, a judgment module, clock recovery module, a clock frequency-division module and a SerDes module. The data space over sampling module adopts the 16-phase equal-interval clock outputted by the PLL module to continuously sample the 24 bit data of 3 bytes, stores the sampled data in 16 groups of registers, and each group includes 24 registers. The corresponding bits of adjacent two groups of registers carry out OR operation to finish the edge detection, the detection results are added together in grouping mode, the fastest sampling clock corresponding to the group of data with the maximum distance value can be used as the recovery clock, the data sampled through the sampling clock can be used as recovery data, the sampling clock is performed with 8-fractional frequency to synchronize the bytes of the recovery data so as to finish the clock data recovery and serial-parallel conversion. The invention has clear structure, higher performance and reliable operation.