Disclosed is an anti-fake method and application using random spray coverage patterns and a digital image contrast technology. The method relates to an anti-fake technology. The method comprises the following steps of A, random spray coverage patterns are formed by a spraying device; B, anti-fake patterns are collected and uploaded; C, operation of a verification end is conducted; D, a verification process is conducted. According to the method, by the cooperation of randomly spraying and code information stickers of commodity identification information, all anti-fake information of the commodities are integrated into entitative random patterns, anti-fake patterns are transmitted and contrasted by using an information technology, the anti-fake information is read to prevent anti-fake vulnerabilities in the circulation of the commodities, uniqueness and unduplicated performance of the commodities are ensured, mechanical random spraying is adopted in mass production, equipment is the same, but an obtained random state set is completely uncontrollable. The random spraying method has a good anti-fake effect, despite the fact that the anti-fake method is simple to operate, but the anti-fake effect is good, risks of being cracked do not exist, the anti-fake cost is low, and the method is easy to query and verify, and has extremely high market popularization and application value.