The invention relates to the technical field of power supplies, and provides a parallel power supply protection circuit and electronic equipment. Each power supply branch comprises a power supply positive electrode interface, a power supply negative electrode interface, a power NMOS tube, a grid voltage bias circuit, a switch tube and a comparator; the power NMOS tube is connected to the negative power line in series, the drain electrode of the power NMOS tube, the first input end of the comparator and the power source negative interface are connected with one another, the source electrode of the power NMOS tube, the second input end of the comparator and the load negative end are connected with one another, and the grid electrode of the power NMOS tube is connected with the grid voltage bias end of the grid voltage bias circuit. The output end of the comparator is connected with the control end of the switching tube, and the access end of the switching tube is connected with the grid voltage bias circuit. According to the technical scheme, the power loss is very small, the universality is high, and the method can be applied to a-48V power supply system.