The invention provides an array substrate, a preparation method thereof, a display panel and a display device, and belongs to the technical field of display. The array substrate comprises a binding area and a non-binding area. The array substrate further comprises a rigid substrate, a driving circuit layer, a light emitting diode layer, a flexible substrate layer and a binding lead layer, whereinthe rigid substrate is arranged in the non-binding area; the driving circuit layer is arranged at one side of the rigid substrate; the light emitting diode layer is arranged at the side, which is awayfrom the rigid substrate, of the driving circuit layer; the flexible substrate layer is arranged in the binding area and located at the same side of the rigid substrate as the driving circuit layer;the binding lead layer is arranged at the side, which is away from the rigid substrate, of the flexible substrate layer, and the binding lead layer is electrically connected with the driving circuit layer; and the binding lead layer and the flexible substrate layer can be bent to the side, which is away from the driving circuit layer, of the rigid substrate along the edge of the rigid substrate. The array substrate can reduce the frame of the display panel.