The invention provides a large-scale efficient farming method of meat ducks and relates to the technical field of farming of poultry. The large-scale efficient farming method of meat ducks comprises the steps of (1) building a greenhouse, closing for fumigating, and opening doors and windows for ventilating; (2) inoculating vaccines to ducklings, and during feeding 2 days before the inoculation ofthe vaccines, mixing well crushed corn, crushed black bean and crushed brown rice in a weight ratio of 3:1:1, boiling the mixture to be half cooked, soaking the mixture in clear water, taking out themixture, adding cooked yoke, and mixing them well; (3) allowing the ducks to exercise in water three times a day for 1 h, feeding the ducks with feed after the exercise, and allowing the ducks to drink water freely; (4) allowing the ducks to exercise once a day for 2 h, feeding the ducks with the feed 5 times a day, allowing the ducks to drink water freely, wherein 10-20 parts of mulberry leaf powder and 2-6 parts of edible salt are added to the feed, decocting isatis root in water, and dropwise administrating 2-3 mL of the decoction to each duck. The large-scale efficient farming method of meat ducks has the advantages of large scale of efficient farming, low farming cost, short marketing time of meat ducks, good meat deliciousness, and high economic benefit.