The invention discloses a control system for fatigue relieving pneumatic ventilation massage seats for an automobile. The control system is composed of a seat back, an air-pressure cavity, a power air tube, an upper air tube, an electronic oscillator, a main air tube, a solenoid valve a, a solenoid valve b, a lower air tube, a seat, seat air vents, back air vents and telescopic massage heads. The electronic oscillator in the seat back controls the air pressure cavity in accordance with procedures to change pressure in the air pressure cavity, so that the seat surface moves along with the air pressure cavity to massage drivers and passengers; the air flow of the seat is controlled by the solenoid valves to enable air to flow out from the chair air vents and the back air vents to achieve ventilation. By means of the control system, fatigue of users who work for a whole day or drive for a long time can be relieved by the seats with the ventilation and massage functions, overall ventilation and massage can be performed on waists and the whole backs of drivers and passengers, and accordingly, fatigue is relieved.