The invention discloses a quadruped bionic system based on the pneumatic muscle. The bionic system uses the pneumatic muscle to simulate the muscle of a quadruped to drive the neck, fore legs, thoracic joint, lumbar joint and hind legs to move, particularly simulate the pneumatic muscle having the actions of the sternocephalicus muscle, brachiocephalic muscle, musculi splenius, superficialis chestmuscle, arm triceps muscle, wrist radial extensor muscle, wrist oblique extensor muscle, wrist ulnar lateral flexor muscle, wrist radial flexor muscle and the like to drive the neck and the fore legsto flex, fold, unfold and rotate, simulate the posterior serratus muscle and the latissimus dorsi muscle to drive the thoracic joint to do lateral bending, pitching and circular rotation motions, simulate the internal oblique muscle and the medius arm muscle to drive the lumbar joint to do lateral bending, pitching and circular rotation motions, and simulate the pneumatic muscle having the actions of tensor fascia lata, quadriceps femoris, semitendinosus, tibialis anterior, peroneal longus, gastrocnemius and the like to drive the hind legs to flex, fold and unfold. According to the quadrupedbionic system based on the pneumatic muscle, the pneumatic muscle is used for driving, the quadruped bionic system based on the pneumatic muscle has the beneficial effects of being compact in structure, clean and good in explosion-proof performance and can be used for teaching and demonstration.