33results about How to "Delayed resistance" patented technology

The present invention relates to a nucleic acid sequence for detecting herbicide-tolerant soybean plant DBN9004 and a detection method thereof, wherein the nucleic acid sequence of the soybean plant comprises SEQ ID NO: 1 or its complementary sequence, or SEQ ID NO: 2 or its complementary sequence complementary sequence. The transgenic soybean event DBN9004 of the present invention has good tolerance to glyphosate herbicide and glufosinate-ammonium herbicide, has no effect on the yield, and the detection method can accurately and quickly identify whether the biological sample contains the DNA of the transgenic soybean event DBN9004 molecular.

The present invention provides methods for treating a EGFR-mutant cancer in a patient by administering a selective CDK4 / 6 inhibitor described herein in combination or alternation with an EGFR-TKI to delay or reverse acquired resistance to previously administered EGFR-TKIs. In addition, methods for treating a EGFR-mutant cancer in a patient by administering a selective CDK4 / 6 inhibitor described herein in combination or alternation with an EGFR-TKI are provided wherein an intrinsically EGFR-TKI resistant EGFR-mutant cancer is sensitized to the effects of the EGFR-TKI.

Disclosed are a semiconductor structure and a forming method thereof. In one form, a semiconductor structure includes: a base; gate structures arranged discretely on the base, including gate contact regions used for contact with gate plugs; source / drain doped regions, including source / drain contact regions and source / drain connection regions; dielectric structure layers, located on the base on sides of the gate structures and covering the source / drain doped regions and the gate structures; source / drain contact structures, being in contact with the source / drain doped regions, where the source / drain contact structures are an integrated structure, and include source / drain plugs penetrating dielectric structure layers of the source / drain contact regions and source / drain contact layers located in dielectric structures of the source / drain connection regions, top surfaces of the source / drain contact layers are lower than top surfaces of the source / drain plugs, and the source / drain contact structures and the dielectric structure layers enclose spaced openings; spaced dielectric layers, filling the spaced openings; and gate plugs, located on tops of the gate structures in the gate contact regions and in contact with the gate structures. The source / drain contact structures of implementations of the present disclosure are an integrated structure, which improves performance of electrical connection between the source / drain plugs and the source / drain contact layers.

The invention relates to a combination of a FGFR inhibitor and an IGF1R inhibitor. The combination is for use in the treatment of a proliferative disorder, in particular for the treatment of cancer. The FGFR inhibitor and the IGFR inhibitor can be administered simultaneously, separately or sequentially. The invention further relates to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a combination according to the invention.

The invention discloses a quadric-chlorantraniliprole insecticidal composition, which comprises the following effective components: quadric-chlorantraniliprole and cartap at the weight ratio of (1:60) to (60:1). The insecticidal composition disclosed by the invention has the advantages of being wide in insecticidal range, long in lasting period, low in toxicity, low in residue, free of a public hazard and safe to environment; by virtue of a compound preparation, the insecticidal efficacy is improved; the safety is increased; and the environmental pollution is reduced.

The invention provides a paddy field weeding composition and application thereof, and belongs to the field of weeding agents. After effective components including pyroxasulfone and pyriftalid are compounded, paddy field weed treating and preventing effects are obvious, the chemical preparations have a significant synergistic effect so that the dosage can be reduced, pesticide resistance of weeds to a single preparation is delayed, and the paddy field weeding composition is economical, efficient and environmentally friendly. The paddy field weeding composition includes the effective componentsand auxiliary components, wherein the effective components include pyroxasulfone and pyriftalid, the weight ratio of pyroxasulfone to pyriftalid is 1:(0.1-10), and the total weight percentage of pyroxasulfone and pyriftalid which serve as the effective components in the paddy field weeding composition is 1%-90%; the auxiliary components include carriers and auxiliaries, wherein the carriers are one or more of water, solvent and filler, and the auxiliaries include at least one surface active agent.

The invention discloses an insecticidal composition containing Empedobacter brevis and monosultap. The composition contains Empedobacter brevis and monosultap, wherein a weight ratio of Empedobacter brevis to monosultap is 1:60 to 60:1. The insecticidal composition has the advantages of good insecticidal fast action effect, long persistent period, low toxicity, low residual, no pollution, good safety to environment, improvement of the insecticidal effect, safety increase, and reduction of environment pollution.

The invention discloses a pesticidal composition containing empedobacter brevis and bisultap. The pesticidal composition includes the empedobacter brevis and the bisultap as active components, wherein the weight ratio of the empedobacter brevis to the bisultap is 1:60-60:1. The pesticidal composition has quick effects and long lasting period, is free of residue and pollution, is safe to environment, is improved in pesticidal effects due to the form of composite preparation, is improved in safety and reduces environment pollution.

The invention discloses an agricultural insecticide composition. The agricultural insecticide composition contains active components including spinetoram and padan, wherein the weight ratio of the spinetoram to the padan is 1:1-100. The composition can be applied to preventing and treating crop insect damage caused by rice stem borers. The agricultural insecticide composition has the advantages of being wide in insect killing range, long in lasting period, low in toxicity, low in residue, free of pollution and safe to environment, improving the insect killing effect, relieving environmental pollution and the like.

The invention discloses an insecticidal composition containing Empedobacter brevis and monosultap. The composition contains Empedobacter brevis and monosultap, wherein a weight ratio of Empedobacter brevis to monosultap is 1:60 to 60:1. The insecticidal composition has the advantages of good insecticidal fast action effect, long persistent period, low toxicity, low residual, no pollution, good safety to environment, improvement of the insecticidal effect, safety increase, and reduction of environment pollution.

A pesticide composition for controlling Fusarium head blight, which contains 1 to 150 parts by weight of jinggangmycin and 1 to 30 parts by weight of tebuconazole. The pesticide composition of the present invention has an obvious synergistic effect when used for controlling Fusarium head blight, can remarkably enhance the effect of controlling Fusarium head blight, and increase the ability of the human being in controlling Fusarium head blight of grain crops.

The invention discloses a pesticidal composition containing empedobacter brevis and bisultap. The pesticidal composition includes the empedobacter brevis and the bisultap as active components, wherein the weight ratio of the empedobacter brevis to the bisultap is 1:60-60:1. The pesticidal composition has quick effects and long lasting period, is free of residue and pollution, is safe to environment, is improved in pesticidal effects due to the form of composite preparation, is improved in safety and reduces environment pollution.

The invention discloses a quadric-chlorantraniliprole insecticidal composition, which comprises the following effective components: quadric-chlorantraniliprole and cartap at the weight ratio of (1:60) to (60:1). The insecticidal composition disclosed by the invention has the advantages of being wide in insecticidal range, long in lasting period, low in toxicity, low in residue, free of a public hazard and safe to environment; by virtue of a compound preparation, the insecticidal efficacy is improved; the safety is increased; and the environmental pollution is reduced.