33results about How to "Delayed resistance" patented technology

An organic light emitting diodes display device includes a number of data lines, scan lines, and cathode electrodes. These scan lines are perpendicular to the data lines to form a number of pixels, each of which possess a pixel area respectively. All the pixels areas form a pixel area array. These cathode electrodes are parallel to the scan lines or data lines and partially cover the pixel area array. Spaces between each two cathode electrodes are above the scan lines or data lines to avoid the parasitic capacitance between the cathode electrodes and scan lines or data lines. And thus the resistance capacitance time delay is prevented.

The present invention relates to a nucleic acid sequence for detecting herbicide-tolerant soybean plant DBN9004 and a detection method thereof, wherein the nucleic acid sequence of the soybean plant comprises SEQ ID NO: 1 or its complementary sequence, or SEQ ID NO: 2 or its complementary sequence complementary sequence. The transgenic soybean event DBN9004 of the present invention has good tolerance to glyphosate herbicide and glufosinate-ammonium herbicide, has no effect on the yield, and the detection method can accurately and quickly identify whether the biological sample contains the DNA of the transgenic soybean event DBN9004 molecular.

Pharmaceutical compositions are provided that include an antibiotics, but that include ingredients that counteract the effect of that antibiotic on wound healing, without altering the bactericidal properties of the antibiotic. These pharmaceutical compositions include an effective amount of 1) an imidazoquinoline having toll-like receptor 7 (TLR7) ligand activity, 2) an immunostimulatory K-type CpG oligodeoxynucleotide (ODN) comprising an unmethylated CpG motif, 3) an antibiotic, and 4) a surfactant, wherein the composition is formulated for topical administration. Methods for accelerating wound healing are also provided. These methods include topically administering the disclosed compositions. The wound can be in the skin or in the eye.

A composite insecticide in the form of wettable powder for preventing and eliminating the pests of rice, fruit tree, vegetables, etc is prepared phoxim, acephate, assistant and filler through adsorptive mixing, and pulverizing.

The present invention provides methods for treating a EGFR-mutant cancer in a patient by administering a selective CDK4 / 6 inhibitor described herein in combination or alternation with an EGFR-TKI to delay or reverse acquired resistance to previously administered EGFR-TKIs. In addition, methods for treating a EGFR-mutant cancer in a patient by administering a selective CDK4 / 6 inhibitor described herein in combination or alternation with an EGFR-TKI are provided wherein an intrinsically EGFR-TKI resistant EGFR-mutant cancer is sensitized to the effects of the EGFR-TKI.

The invention discloses preparation and prevention and treatment application of mycoprotein in a bacillus subtilis fermentation product. The preservation number of a bacillus subtilis strain DR22 is CGMCC NO: 19784. The bacillus subtilis strain DR22 has the advantages of being high in growth speed, high in sporulation quantity, high in stress resistance, rich in active products, high in mycoprotein and the like. The method is characterized in that a bacillus subtilis solid fermentation technology and a mycoprotein preparation technology are adopted, and the preparation process comprises the following steps: (1) activating strains to obtain activated strains; (2) carrying out multiplication culture to prepare a seed solution of a bacterial solution; (3) carrying out fermentation culture toprepare a microbial inoculum; and (4) preparing mycoprotein, namely fermenting thalli, drying, crushing, sieving, leaching, precipitating, carrying out isoelectric point acid precipitation, centrifugally collecting precipitates, and drying to remove moisture and mycoprotein. The final control effect can reach 73.76%, the control effect is stable, and a good biological control choice is provided for controlling tobacco mosaic virus diseases.

The present invention provides methods for treating a EGFR-mutant cancer in a patient by administering a selective CDK4 / 6 inhibitor described herein in combination or alternation with an EGFR-TKI to delay or reverse acquired resistance to previously administered EGFR-TKIs. In addition, methods for treating a EGFR-mutant cancer in a patient by administering a selective CDK4 / 6 inhibitor described herein in combination or alternation with an EGFR-TKI are provided wherein an intrinsically EGFR-TKI resistant EGFR-mutant cancer is sensitized to the effects of the EGFR-TKI.

Disclosed are a semiconductor structure and a forming method thereof. In one form, a semiconductor structure includes: a base; gate structures arranged discretely on the base, including gate contact regions used for contact with gate plugs; source / drain doped regions, including source / drain contact regions and source / drain connection regions; dielectric structure layers, located on the base on sides of the gate structures and covering the source / drain doped regions and the gate structures; source / drain contact structures, being in contact with the source / drain doped regions, where the source / drain contact structures are an integrated structure, and include source / drain plugs penetrating dielectric structure layers of the source / drain contact regions and source / drain contact layers located in dielectric structures of the source / drain connection regions, top surfaces of the source / drain contact layers are lower than top surfaces of the source / drain plugs, and the source / drain contact structures and the dielectric structure layers enclose spaced openings; spaced dielectric layers, filling the spaced openings; and gate plugs, located on tops of the gate structures in the gate contact regions and in contact with the gate structures. The source / drain contact structures of implementations of the present disclosure are an integrated structure, which improves performance of electrical connection between the source / drain plugs and the source / drain contact layers.

The invention relates to a combination of a FGFR inhibitor and an IGF1R inhibitor. The combination is for use in the treatment of a proliferative disorder, in particular for the treatment of cancer. The FGFR inhibitor and the IGFR inhibitor can be administered simultaneously, separately or sequentially. The invention further relates to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a combination according to the invention.

The invention discloses a phenylpyrazole zwitterionic compound and application thereof in control of resistant pests. The phenylpyrazole zwitterionic compound belongs to a dipolar compound containing positive and negative charges in a delocalization state in the structure, and a molecule contains a pharmacophore phenylpyrazole group of a gamma-aminobutyric acid receptor and a zwitterionic group of a nicotinic acetylcholine receptor that are used for acting on a nerve parts of an insect, so that compared with a single phenylpyrazole insecticide acting on the gamma-aminobutyric acid receptor of the insect, the phenylpyrazole zwitterionic compound are used for simultaneously acting on two different target spots of the nerve part of the insect, synergistic interaction can be achieved, the purpose of overcoming resistance is achieved, and the high efficiency of the phenylpyrazole zwitterionic compound for resistant pests is showed; and in addition, a control spectrum can be added, and therefore, the application prospect is very wide.

The invention relates to an insecticidal composition and particularly relates to an insecticidal composition comprising a first active substance tolfenpyrad and a second active substance cycloxaprid. The insecticidal composition comprises tolfenpyrad and cycloxaprid, wherein the weight ratio of tolfenpyrad to cycloxaprid is 1:100-100:1. The insecticidal composition has the advantages that tolfenpyrad and cycloxaprid are compounded according to the certain weight ratio, so that the gain effect in preventing and controlling lepidoptera and homoptera insects in the field crops is achieved, the single-dosage use amount of tolfenpyrad and cycloxaprid is reduced, the use cost is reduced and the risk of insecticide resistance generated by insects is reduced.

The invention discloses an ultra-low volume liquid containing ametoctradin and benzamide fungicide composition, and belongs to the field of pesticides. The ultra-low volume liquid consists of components in percentage by mass as follows: 0.1%-40% of an active component (I) ametoctradin, 1%-40% of an active component (II) and the balance of a solvent and an assistant, wherein the active component (II) is one of metalaxyl, benalaxyl and oxadixyl, and the assistant is one or more of surfactants or cosolvents. The provided ultra-low volume liquid containing ametoctradin and phenyl and benzamide fungicide composition aims at overcoming the defects of low work efficiency, high labor intensity, large water need and poor safety in traditional agricultural control as well as solving the problems of single control effect, obvious resistance, short duration and the like of a pesticide, and a preparation method of the ultra-low volume liquid is provided.

A bactericidal composition for preventing and treating wheat powdery mildew, which consists of the following substances in parts by mass: 8 parts of prochloraz, 3 parts of emodin methyl ether, 8 parts of tetrachlorantraniliprole, and 3 parts of tristyrylphenol polyoxyethylene ether 8 parts, 8 parts of berberine, 8 parts of distyryl phenol formaldehyde condensate polyoxyethylene ether, 2 parts of calcium dodecylbenzenesulfonate, 8 parts of xylene.

The invention discloses a thiamethoxam and imidaclothiz complex insecticide which is characterized in that the active ingredients comprise thiamethoxam and imidaclothiz, wherein the residual aid or excipient is supplemented to the 100 percent of insecticide; and the weight ratio of thiamethoxam to imidaclothiz is (1-85):(1-85). The insecticide has a good effect of removing rice planthopper, aphid, leafhopper, thrips and other homoptera insects with easy resistance and can inhibit the insects to generate medicine resistance on a single thiamethoxam and imidaclothiz preparation, and the actual using effect is obvious. The thiamethoxam and imidaclothiz are complexed, so that the effects of effectively controlling most of sucking pests and reducing the environmental pollution are achieved, the pesticide effect and lasting period are improved, the labor cost of farmers is reduced, and the insecticide has good economic benefits.

The invention relates to a bactericidal composition and application thereof in crop diseases. The composition comprises effective active components, and the effective active components comprise a pyrazole amide compound and a triazole bactericide. The bactericidal composition disclosed by the invention has good synergistic and persistent effects, and the control effect is higher than that of a single agent; the pesticide dosage is reduced, the residual quantity of the pesticide on crops is reduced, the pesticide dosage is reduced, and the generation of resistance of diseases is delayed. The bactericidal composition disclosed by the invention expands the bactericidal spectrum, and has relatively high activity on various diseases such as cucumber powdery mildew, wheat powdery mildew, soybean rust disease, corn rust disease, wheat septospora leaf blight, garlic rust disease, rice sheath blight and the like.

The invention discloses an application of a pesticide compound for preventing and controlling gray mold in preventing and controlling tobacco gray mold. Iprodione, tebuconazole and pyrroloquinoline quinone are taken as main active ingredients of the pesticide compound; the weight ratio of iprodione to tebuconazole is (1-6):(1-6); the total weight of iprodione and tebuconazole is 25-40% of the weight of the pesticide compound. The compound, compared with single dosage, has an obvious synergistic effect in preventing and controlling gray mold; the pesticide compound is capable of overcoming anddelaying the drug resistance of pathogenic bacteria; dosage and cost of pesticide are reduced.

The invention discloses a quadric-chlorantraniliprole insecticidal composition, which comprises the following effective components: quadric-chlorantraniliprole and cartap at the weight ratio of (1:60) to (60:1). The insecticidal composition disclosed by the invention has the advantages of being wide in insecticidal range, long in lasting period, low in toxicity, low in residue, free of a public hazard and safe to environment; by virtue of a compound preparation, the insecticidal efficacy is improved; the safety is increased; and the environmental pollution is reduced.

The invention discloses an ultra-low volume liquid containing an ametoctradin composition, belonging to the field of pesticides. The ultra-low volume liquid comprises 0.1-30% of ametoctradin as an active constituent (I), 1-40% of an active constituent (II), and the balance of a solvent and an aid, wherein the active constituent (II) is selected from one of propamocarb, iprovalicarb, diethofencarb and benthiavalicarb-isopropyl ester, and the aid is selected from one or more of a surfactant, a synergist and a penetrating agent. Specific to the defects of low working efficiency, large labor intensity, high water consumption and poor safety regarding to the traditional agricultural control and the problems of single control effect, obvious resistance, short lasting period and the like of a chemical, the invention provides the ultra-low volume liquid containing the ametoctradin composition and further provides a preparation method of the ultra-low volume liquid.

The invention provides a paddy field weeding composition and application thereof, and belongs to the field of weeding agents. After effective components including pyroxasulfone and pyriftalid are compounded, paddy field weed treating and preventing effects are obvious, the chemical preparations have a significant synergistic effect so that the dosage can be reduced, pesticide resistance of weeds to a single preparation is delayed, and the paddy field weeding composition is economical, efficient and environmentally friendly. The paddy field weeding composition includes the effective componentsand auxiliary components, wherein the effective components include pyroxasulfone and pyriftalid, the weight ratio of pyroxasulfone to pyriftalid is 1:(0.1-10), and the total weight percentage of pyroxasulfone and pyriftalid which serve as the effective components in the paddy field weeding composition is 1%-90%; the auxiliary components include carriers and auxiliaries, wherein the carriers are one or more of water, solvent and filler, and the auxiliaries include at least one surface active agent.

The invention discloses a pesticidal composition. The pesticidal composition contains active components flubendiamide and cartap, wherein the weight ratio of the flubendiamide to the cartap is 1: (1-100). The pesticidal composition is applicable to control of crop diseases caused by rice-stem borer. The pesticidal composition has the advantages of wide pesticidal range, long duration, low toxicity, low residue, no pollution, environmental safety, improvement on the pesticidal effect, reduction in environment pollution, and the like.

The invention relates to application of a synergist of a herbicide, in particular to application of a polyether compound as the synergist of the herbicide, and belongs to the technical field of pesticides. According to the application of the R1O(CH2CHOH)nR2 or the salt of the R1O(CH2CHOH)nR2 serving as the synergist of the herbicide, R1 is alkyl or phenolic group; R2 is-H,-O (CH2CHOH) mH or-O (CH2CH2CHOH) mH; and n is 1 to 50, and m is 1 to 50. The weeding composition has the advantages of reducing the use amount of other herbicides, reducing the use amount of chemical pesticides, increasing the weeding effect and the effect of preventing and removing resistant weeds, and is safe to the environment.

The invention discloses an insecticidal composition containing Empedobacter brevis and monosultap. The composition contains Empedobacter brevis and monosultap, wherein a weight ratio of Empedobacter brevis to monosultap is 1:60 to 60:1. The insecticidal composition has the advantages of good insecticidal fast action effect, long persistent period, low toxicity, low residual, no pollution, good safety to environment, improvement of the insecticidal effect, safety increase, and reduction of environment pollution.

The invention discloses an agricultural insecticide composition. The agricultural insecticide composition contains active components including spinetoram and padan, wherein the weight ratio of the spinetoram to the padan is 1:1-100. The composition can be applied to preventing and treating crop insect damage caused by rice stem borers. The agricultural insecticide composition has the advantages of being wide in insect killing range, long in lasting period, low in toxicity, low in residue, free of pollution and safe to environment, improving the insect killing effect, relieving environmental pollution and the like.

The invention provides a barley field weeding composition and an application thereof, and belongs to the field of herbicides. Active ingredients of tralkoxydim and halauxifen-methyl are selected to compound, then weeds can be effectively controlled, and the phytotoxicity is reduced, especially for the barley field weeds, the weeding effect is particularly significant. The barley field weeding composition includes the active ingredients and auxiliary ingredients, wherein the active ingredients are the halauxifen-methyl and the tralkoxydim, and the weight ratio of the halauxifen-methyl to the tralkoxydim is 1:2-32. The weight of the active ingredients of the halauxifen-methyl and the tralkoxydim accounts for 5%-95% of the total weight of the barley field weeding composition. The auxiliary ingredients include carriers and auxiliaries, the carriers are one or more of water, solvents or fillers, and the auxiliaries include at least one surfactant.

The invention discloses an insecticidal composition containing Empedobacter brevis and monosultap. The composition contains Empedobacter brevis and monosultap, wherein a weight ratio of Empedobacter brevis to monosultap is 1:60 to 60:1. The insecticidal composition has the advantages of good insecticidal fast action effect, long persistent period, low toxicity, low residual, no pollution, good safety to environment, improvement of the insecticidal effect, safety increase, and reduction of environment pollution.

The invention relates to a herbicidal composition containing benzobicyclon, ipfencarbazone and anilofos. The herbicidal composition has a synergistic effect, wherein the mass ratio of the benzobicyclon to the ipfencarbazone to the anilofos is (1-50):(1-60):(1-50), preferably (1-35):(5-30):(5-35), and most preferably (5-15):(10-20):(10-20); and the mass ratio of the benzobicyclon to the ipfencarbazone is (5-15):(10-20), the mass ratio of the benzobicyclon to the anilofos is (5-15):(10-20), and the mass ratio of the ipfencarbazone to the anilofos is (10-20):(10-20).

The invention discloses a pesticidal composition containing empedobacter brevis and bisultap. The pesticidal composition includes the empedobacter brevis and the bisultap as active components, wherein the weight ratio of the empedobacter brevis to the bisultap is 1:60-60:1. The pesticidal composition has quick effects and long lasting period, is free of residue and pollution, is safe to environment, is improved in pesticidal effects due to the form of composite preparation, is improved in safety and reduces environment pollution.

The invention discloses a quadric-chlorantraniliprole insecticidal composition, which comprises the following effective components: quadric-chlorantraniliprole and cartap at the weight ratio of (1:60) to (60:1). The insecticidal composition disclosed by the invention has the advantages of being wide in insecticidal range, long in lasting period, low in toxicity, low in residue, free of a public hazard and safe to environment; by virtue of a compound preparation, the insecticidal efficacy is improved; the safety is increased; and the environmental pollution is reduced.