The application belongs to the field of preparation and application of catalysts, and provides a preparation method of a catalyst for synthesizing 2,6-diethyl anilino ethyl
propyl ether, wherein the catalyst uses
copper and aluminum salt as a
metal source and an alkali solution as a precipitant, a
copper-aluminum
spinel catalyst is prepared by using a chemical co-
precipitation method, and the catalyst is applied to the synthesis reaction of 2,6-diethyl anilino ethyl
propyl ether which is an important intermediate of
propamocarb. After
process optimization, the application has the advantages of strong reaction selectivity, high yield, good color and high purity of the product, easy availability of the reaction
raw material, simple operation, simple post-treatment, and repeated cyclic use of the
copper-aluminum
spinel catalyst, and not only meets the requirements of
green chemistry, but also has important significance for energy saving and emission reduction.