The utility model discloses an adjustable packaging box creasing die which comprises a die base, a mounting groove, a limiting plate and an adjusting mechanism. According to the mold, the mounting groove is formed in the top middle end of the mold base, the inner bottom end of the mounting groove is connected with at least two sets of limiting plates, the limiting plates are connected with the adjusting mechanism, the adjusting mechanism comprises the middle base, the top plate, the bottom plate, the movable mechanism and other assemblies, and the adjusting mechanism is connected with the mounting groove in a modularized connection mode; and the movable mechanism comprises an overturning plate, a connecting arm, a guide rod, a sliding block, a partition plate, a driving mechanism and other assemblies, the overturning plate can be in linkage through the driving mechanism to conduct overturning so that pressing grooves of different sizes can be obtained through adjustment, creasing can be conveniently conducted on packaging boxes of different sizes or different requirements, and the practicability is high. Disassembly and replacement of the indentation mold are reduced, and the indentation efficiency is improved.