The invention discloses a cable arrangement device. The cable arrangement device includes a first wire separating block, a second wire separating block, a box body and a pressing plate, wherein a plurality of first arc-shaped grooves are formed in the upper side surface of the first wire separating block, the first wire separating block is vertically and slidably arranged in a first mounting trough, a first spring is arranged between the first mounting trough and the first wire separating block, a plurality of second arc-shaped grooves are formed in the upper side surface of the second wire separating block, the second wire separating block is vertically arranged in a second mounting trough in a sliding mode, a second spring is arranged between the second mounting trough and the second wire separating block, the first mounting trough and the second mounting trough are arranged in the box body side by side, a mounting plate is fixedly arranged at the upper end of the right side of the box body, sliding rails are arranged on the upper side surface of the mounting plate, sliding blocks are arranged on the lower side of the pressing plate, the sliding blocks are arranged on the slidingrails in a sliding mode, the mounting plate is further provided with an air cylinder, a telescopic rod of the air cylinder is connected with a pushing plate, and the pushing plate is arranged on thelower side of the pressing plate. According to the cable arrangement device, arrangement can be conducted on interlaced cables at the same time, arrangement speed is quick, and construction speed is improved.