The invention discloses a permanent magnet variable frequency shield pump. The permanent magnet variable frequency shield pump comprises a pump body, an impeller, a magnetoelectric driver, an isolation assembly and a frequency converter; the magnetoelectric driver comprises a casing, a stator assembly and a rotor assembly (a central shaft, a rotor, a magnetic shielding layer and a permanent magnet); the isolation assembly is provided with a rotor sheath sleeving the outside of the permanent magnet, an isolation sheath sleeving the outside of the rotor sheath, and a front separator plate and asealing rear plate which correspondingly block two ends of the isolation sheath, the isolation sheath is fixedly connected with the front separator plate and abuts against the sealing rear plate, thefront separator plate is detachably connected with the casing, a second end of the isolation sheath is sleeved with an isolation sleeve sizing block, and an annular sealing gasket is arranged betweenthe sealing rear plate and the inner wall of the isolation sheath; and a liquid passing gap is arranged between the rotor sheath and the isolation sheath, a liquid passing channel is arranged on the central shaft, and a pump cavity, the liquid passing channel and the liquid passing gap communicate with one another. The permanent magnet variable frequency shield pump can adjust the output torque and the output frequency, and is energy-saving, efficient and environment-friendly; and the permanent magnet variable frequency shield pump is of a detachable structure and is easy to disassemble and maintain; and full sealing is achieved, and leakage is avoided.