The invention relates to an expressway tunnel group guiding setting system based on psychological rotation. The expressway tunnel group guiding setting system comprises an initial entering section tunnel entering a tunnel group, a final section tunnel driving out of the last tunnel of the tunnel group, and middle section tunnels of all middle combined tunnels except the initial entering section tunnel and the final section tunnel. A spherical delineator is arranged on the initial entering section tunnel, a multi-ring delineator and a multi-ring indentation delineator are arranged on the middle section tunnel, a single-ring delineator is arranged on the ending section tunnel, and cat-claw-shaped warning guide marks are arranged in front of the initial entering section tunnel and the ending section tunnel. A cat-claw-shaped light reflecting ring is arranged on the side wall in the middle hole of the straight line section of the tunnel, a tunnel sickle-shaped light reflecting ring is arranged on the top in the middle hole of the straight line section of the tunnel, and a cat-ear-shaped light reflecting ring is arranged on the curve section of the tunnel. By setting the entrance guiding information and the in-tunnel continuous guiding information, the guiding information design scheme is more continuous, the direction feeling of a driver is improved, the tunnel entering alertness consciousness of the driver is effectively improved, the visual repeated transition effect in the tunnel group driving process is relieved, the expressway tunnel group driving environment is comprehensively improved, the driving safety is guaranteed, and the driving safety is improved. Meanwhile, energy consumption of tunnel group lighting facilities is reduced, and engineering cost is saved.