The invention discloses an efficient carton customization machine. The efficient carton customization machine comprises a base seat, supporting racks arranged to the top end face of the base seat in abilateral symmetry manner and a sliding rack arranged between the left supporting rack and the right supporting rack, wherein the bottom of the sliding rack is fixedly provided with an installation block, the installation block is internally provided with a sliding slot with the opening being downward, the sliding slot is internally and slidably provided with a first sliding block, the bottom endface of the first sliding block is internally provided with a first motor, the bottom of the first motor is in power connection with a drilling head, the sliding rack is internally provided with a sliding cavity which communicates with the sliding slot and extends upwards, the sliding cavity is internally and slidably provided with a sliding seat located above the first sliding block, the slidingseat is internally provided with a first rotating cavity running through front and back, the part, on the rear side of the sliding cavity, of the sliding rack is internally provided with a second rotating cavity in a left and right extending manner, and a first rotating shaft extending front and back is installed between the second rotating cavity and the sliding cavity in a rotating fit manner.