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74results about How to "Sufficient ability" patented technology
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Cyclodextrin-based polymers for therapeutics delivery
ActiveUS7270808B2Improve drug stabilityImprove solubilityAntibacterial agentsBiocideSolubilityPresent method
The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
Owner:CERULEAN PHARMA
Wet surface adhesives
InactiveUS6855386B1Overcome environmentalOvercome safety undesirabilityEnvelopes/bags making machineryFilm/foil adhesivesMeth-Solvent
A wet stick pressure sensitive adhesive comprising the solventless polymerization product of: a) about 30 to about 70 parts by weight of an (meth)acrylate ester monomer wherein the (meth)acrylate ester monomer, when homopolymerized, has a Tg of less than about 10° C.; b) about 70 to about 30 parts by weight of a hydrophilic acidic comonomer; and c) about 10 to 100 parts based on 100 parts of the sum of components (a+b) of a non-reactive plasticizing agent, wherein the pressure sensitive adhesive adheres to wet substrate surfaces and a method of making.
Owner:3M INNOVATIVE PROPERTIES CO
Biodegradable polymer compositions, compositions and uses related thereto
ActiveUS7163697B2Efficient productionSufficient abilityPowder deliveryCosmetic preparationsMicrosphereMedicine
The present application is directed to biodegradable polymers, compositions, including microspheres and nanospheres, formed of such polymers, and methods of using such polymers and compositions. In certain embodiments, the subject polymer compositions include therapeutic agents, optionally providing sustained release of the encapsulated agent after administration to a patient.
Owner:THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
Treatment of cancer
InactiveUS20110160159A1Efficient productionSufficient abilityBiocideOrganic active ingredientsMedicineCRLX101
Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101.
Owner:CERULEAN PHARMA +1
Lapachone delivery systems, compositions and uses related thereto
InactiveUS6890950B2Improve solubilityImprove bioavailabilityBiocideOrganic chemistryBeta-CyclodextrinsDelivery system
In part, the present invention is directed to a system comprising a lapachone or a prodrug thereof and a polymer, such as a biocompatible and optionally biodegradable polymer, methods for treatment using the subject polymer compositions, and methods of making and using the same. In another part, the present invention includes inclusion complexes of a lapachone or a prodrug thereof and a cyclodextrin, preferably a β-cyclodextrin, such as hydroxypropyl β-cyclodextrin, e.g., to improve the solubility of the lapachone or prodrug thereof.
Owner:CASE WESTERN RESERVE UNIV
Latent, over-tackified, adhesives and methods of use
InactiveUS20050061435A1Aggressive and permanent tackSufficient abilityNon-macromolecular adhesive additivesLayered productsPressure sensitiveChemistry
Methods of applying a pressure sensitive adhesive to a substrate and adhering substrates together that includes applying a latent, over-tackified, adhesive to a substrate and applying a plasticizing agent to activate the latent, over-tackified, adhesive to form a pressure sensitive adhesive.
Owner:3M INNOVATIVE PROPERTIES CO
Detergent composition containing branched alcohol alkoxylate and compatibilizing surfactant, and method for using
ActiveUS20070123447A1Sufficient abilityNon-ionic surface-active compoundsOrganic detergent compounding agentsAlcoholSURFACTANT BLEND
A detergent composition is provided according to the invention. The detergent composition includes a branched alcohol alkoxylate having the formula: wherein R1 is a C2-C20 alkyl, R2 is H or a C1-C4 alkyl, n is 2-20, and m is 1-40, and a compatibililizing surfactant. The compatibilizing surfactant can be selected so that an aqueous composition containing 5 wt. % of the branched alcohol alkoxylate and at least 2.5 wt. % of the compatibilizing surfactant provides a clear aqueous composition. A clear aqueous composition refers to an aqueous composition that is free of haze visible to the naked eye. In general, a clear aqueous composition resembles a composition containing only water. A method for using the detergent composition is provided.
Owner:ECOLAB USA INC
Branched Surfactant Having Fluoroalkyl Group And Hydrocarbon Group
InactiveUS20080093582A1High abilityLow compatibilityInorganic/elemental detergent compounding agentsOrganic chemistryEtherAmmonium
The present invention relates to a surfactant represented by Formula (I): [Formula 1]wherein Rf represents a fluoroalkyl group which may have an ether bond; Rh represents an alkyl group; r represents 1 or 0; when r=0, Z1 and Z2 represent (CH2)n1—(X1)p1— and —(X2)q1—, respectively; and when r=1, Z1 and Z2 represent (CH2Y)p2—CH2— and —(CH2Y)q2—, respectively, wherein X1 and X2 may be the same or different and each represents a divalent linking group, p1 represents 0 or 1, q1 represents 0 or 1, n1 represents an integer of 1-10; Y represents O, S or NR, wherein R represents a hydrogen atom, methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl, or t-butyl; p2 and q2 each represent 0 or 1 but are not 0 at the same time; and M represents a hydrogen atom, alkali metal, ½ alkaline earth metal or ammonium.
Owner:DAIKIN IND LTD
Detergent composition containing branched alcohol alkoxylate and compatibilizing surfactant, and method for using
ActiveUS7530361B2Sufficient abilityNon-ionic surface-active compoundsOrganic detergent compounding agentsAlcoholSURFACTANT BLEND
Owner:ECOLAB USA INC
Small gas turbine engine with multiple burn zones
InactiveUS20070234733A1Most efficientImprove stabilityTurbine/propulsion fuel supply systemsContinuous combustion chamberCombustorTurbine
A small gas turbine engine for use in an UAV such as a cruise missile, the gas turbine having a combustor forming a primary burn zone and a secondary burn zone, and in which fuel is injected into both the primary and the secondary burn zones by either a rotary cup injector or a plurality of fuel injector nozzles. The secondary burn zone with separate fuel injection allows for the diameter of the engine to be reduced in size but still allow for adequate power and efficiency to be reached for powering the vehicle. Air flow from the compressor is used to cool the combustor walls before being injected into the combustor, and to pass through and cool the guide nozzles and a main bearing located near the hot section of the combustor prior to being introduced into the combustor.
Owner:FLORIDA TURBINE TECH
Cyclodextrin-based polymers for therapeutic delivery
InactiveUS20130196906A1Delivery problemEfficient productionBiocideSenses disorderAutoimmune conditionAutoimmune disease
Provided are methods relating to the use of CDP-therapeutic agent conjugates for the treatment of a disease or disorder, e.g., autoimmune disease, inflammatory disease, central nervous system disorder, cardiovascular disease, or metabolic disorder. Also provided are CDP-therapeutic agent conjugates, particles comprising CDP-therapeutic agent conjugates, and compositions comprising CDP-therapeutic agent conjugates.
Owner:CERULEAN PHARMA
Implant Made of a Biodegradable Magnesium Alloy
ActiveUS20100082092A1Easy to processImprove material performanceStentsSurgeryBiodegradable magnesium
An implant made in total or in parts of a biodegradable magnesium alloy consisting of Y: 2.0-6.0% by weight, Nd: 1.5-4.5% by weight, Gd: 0-4.0% by weight, Dy: 0-4.0% by weight. Er: 0-4.0% by weight, Zr: 0.1-1.0% by weight, Li:0-0.2% by weight, Al: 0-0.3% by weight, under the condition that a) a total content of Er, Gd and Dy is in the range of 0.5-4.0% by weight and b) a total content of Nd, Er, Gd and Dy is in the range of 2.0-5.5% by weight, the balance being magnesium and incidental impurities up to a total of 0.3% by weight.
Owner:BIOTRONIK AG
Ostomy appliance
ActiveUS20150359656A1Increase reaction forceReduce in quantityNon-surgical orthopedic devicesColostomyBiomedical engineeringOstomy appliances
A one-piece or two-piece ostomy appliance comprising a base plate (1), the base plate comprising an adhesive wafer (11) that comprises a top film (8) and at least one skin-friendly adhesive (9) on a proximal surface thereof, for attaching the base plate to the skin of a user, and a first through-going-hole (5). Further, a convex element (10) is arranged distal to a user-interface of the adhesive wafer and has a second through-going hole (15) of the same diameter as the first through-going hole and being co-axially arranged therewith. The convex element comprises a material which reacts to moisture.
Owner:COLOPLAST AS
Small gas turbine engine with multiple burn zones
InactiveUS7568343B2Most efficientImprove stabilityContinuous combustion chamberTurbine/propulsion fuel supply systemsCombustorCruise missile
Owner:FLORIDA TURBINE TECH
Compositions and methods for treatment of autoimmune and other disease
InactiveUS20110300150A1Effective treatmentEfficient productionOrganic active ingredientsPeptide/protein ingredientsAutoimmune conditionAutoimmune disease
Provided are methods relating to the use of CDP-therapeutic agent conjugates for the treatment of autoimmune disease, inflammatory disease, or cancer. Also provided are CDP-therapeutic agent conjugates, particles comprising CDP-therapeutic agent conjugates, and compositions comprising CDP-therapeutic agent conjugates.
Owner:CERULEAN PHARMA
Playback method for an after-recording operation
InactiveUS7474836B2Sure easySufficient abilityTelevision system detailsElectronic editing digitised analogue information signalsComputer hardwareData preparation
The invention provides an information recording medium, such as an optical disk, having a large capacity and being capable of performing read / write operations at high speeds. The recording medium includes an audio stream prepared for after-recording data, and a audio attribute information having a bit rate information to the recorded audio stream as a management information. A recorder according to the invention has a check unit for checking, in advance, the possibility of after-recording operation of the recorder to the audio stream to be after-recorded with reference to the bit rate information of the audio attribute information.
Owner:PANASONIC CORP
Implant made of a biodegradable magnesium alloy
ActiveUS20130060326A1Easy to processImprove material performanceStentsSurgeryMaterials scienceBiodegradable magnesium
An implant made in total or in parts of a biodegradable magnesium alloy consisting of Y: 2.0-6.0% by weight, Nd: 1.5-4.5% by weight, Gd: 0-4.0% by weight, Dy: 0-4.0% by weight, Er: 0-4.0% by weight, Zr: 0.1-1.0% by weight, Li:0-0.2% by weight, Al: 0-0.3% by weight, under the condition that a) a total content of Er, Gd and Dy is in the range of 0.5-4.0% by weight and b) a total content of Nd, Er, Gd and Dy is in the range of 2.0-5.5% by weight, the balance being magnesium and incidental impurities up to a total of 0.3% by weight.
Owner:BIOTRONIK AG
Fire retardant resin composition, method of its production, shaped articles comprising the same, and silica
InactiveUS20060167164A1Good physical propertiesImprove heat resistanceSpecial tyresMixingMicroparticleCarboxylic acid
The present invention has for its object to provide a fire retardant resin composition which is not only halogen-free and, hence, eliminating the adverse effect to the environment and human physiology but also reflecting an excellent fire retardancy imparted to a polyphenol having inherently favorable physical properties and heat resistance. The present invention is a fire retardant resin composition comprising a polyphenol compound and an inorganic microfine particle, wherein said polyphenol compound has such a structure that aromatic units each having at least one phenolic hydroxyl group are connected to one another through an organic unit containing two or more carbon atoms, and said inorganic microfine particle is a product of hydrolysis and condensation of an alkoxide compound and / or a carboxylic acid salt compound.
Owner:NIPPON SHOKUBAI CO LTD
Image processing system, display apparatus and image processing method
InactiveUS20070216766A1Efficient executionReduce processing loadDigital computer detailsCathode-ray tube indicatorsData bufferImage resolution
An image processing system for stereoscopic view using a parallax barrier method includes an image information generating unit that generates image information of a lower resolution than an actual resolution for each of a first to an nth viewpoints. A receiving unit reconfigures the image information, which is stored in a buffer. A combining / transmitting unit generates an image signal for displaying as one stereoscopic image by combining the image information transferred to a unique area of a screen buffer an transmits the image signal to a liquid crystal panel. A transmission speed of the generated signal transmitting unit is set to be at least n times faster than that of the combining / transmitting unit.
Owner:SEIKO EPSON CORP
Ostomy appliance having a lubricating edge
ActiveUS20190117441A1Increase reaction forceReduce in quantityNon-surgical orthopedic devicesColostomyLiquid stateEngineering
Owner:COLOPLAST AS
Implant made of a biodegradable magnesium alloy
InactiveUS20130041455A1Easy to processImprove material performanceStentsSurgeryBiodegradable magnesium
The present invention relates to implants made of a biodegradable magnesium alloy. The inventive implant is made in total or in parts of a biodegradable magnesium alloy comprising:Y: 0-10.0% by weightNd: 0-4.5% by weightGd: 0-9.0% by weightDy: 0-8.0% by weightHo: 0-19.0% by weightEr: 0-23.0% by weightLu: 0-25.0% by weightTm: 0-21.0% by weightTb: 0-21.0% by weightZr: 0.1-1.5% by weightCa: 0-2.0% by weightZn: 0-1.5% by weightIn: 0-12.0% by weightSc: 0-15.0% by weightincidental impurities up to a total of 0.3% by weightthe balance being magnesium and under the condition thata) a total content of Ho, Er, Lu, Tb and Tm is more than 5.5% by weight;b) a total content of Y, Nd and Gd is more than 2% by weight; andc) a total content of all alloy compounds except magnesium is more than 8.5% by weight.
Owner:BIOTRONIK AG
Treatment of cancer
InactiveUS20130029909A1Efficient productionSufficient abilityOrganic chemistryPeptide/protein ingredientsCRLX101Medicine
Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101.
Owner:CERULEAN PHARMA
Mascara applicator with fan tip
InactiveUS20080041407A1Adequate combing abilitySufficient abilityBristlePackaging toiletriesMascaraWire source
A method and apparatus for applying mascara includes a brush formed from a twisted wire core connected to a handle, with a first plurality of bristles extending radially from the core along a substantial portion thereof. The end of the wire core is bent, in some cases, approximately one hundred and eighty degrees, such that a group of bristles fan out from the distal end of the brush, preferably along a plane substantially parallel to the longitudinal axis of the core. The bent portion of the core includes between one and eight, and preferably one and four, turns of the twisted wire.
Owner:RISDON INT
Demodulation circuit and RFID tag including the demodulation circuit
ActiveUS8258862B2DistanceEnergy of electromagnetic wavesAmplitude demodulation by non-linear two-pole elementsSolid-state devicesPower flowSemiconductor materials
Owner:SEMICON ENERGY LAB CO LTD
Cyclodextrin-based polymers for therapeutic delivery
InactiveUS20150005230A1Efficient productionSufficient abilityOrganic active ingredientsSenses disorderAutoimmune conditionAutoimmune disease
Owner:CERULEAN PHARMA
Epitaxial silicon wafer and method for manufacturing same
ActiveUS20120112190A1Reduce in quantitySufficient abilitySemiconductor/solid-state device manufacturingChemical vapor deposition coatingHigh concentrationEpitaxial silicon
It is an object to provide an epitaxial silicon wafer that is provided with an excellent gettering ability in which a polysilicon layer is formed on the rear face side of a silicon crystal substrate into which phosphorus (P) and germanium (Ge) have been doped. A silicon epitaxial layer is grown by a CVD method on the surface of a silicon crystal substrate into which phosphorus and germanium have been doped at a high concentration. After that, a PBS forming step for growing a polysilicon layer is executed on the rear face side of a silicon crystal substrate. By the above steps, the number of LPDs (caused by an SF) that occur on the surface of the epitaxial silicon wafer due to the SF can be greatly reduced.
Owner:SUMCO CORP
Treatment of cancer
InactiveUS20110245201A1Efficient productionSufficient abilityBiocideOrganic chemistryMedicineTopoisomerase inhibitor
Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101.
Owner:CERULEAN PHARMA
Thermally sensitive recording medium
InactiveUS7312176B2Improve stabilityImprove compatibilityRecording apparatusAblative recordingPhotochemistryRecording media
Owner:NIPPON PAPER IND CO LTD
Treatment of cancer
InactiveUS20130164282A1Efficient productionSufficient abilityOrganic active ingredientsBiocideMedicineTopoisomerase inhibitor
Owner:CERULEAN PHARMA
Cement admixture and cement composition
The cement admixture of the present invention can improve the workability by displaying sufficient viscosity decreasing ability and initial dispersing ability even under a low temperature environment as well as high dispersing ability and dispersion retaining ability even in a high water reducing ratio range. The above-mentioned cement admixture comprises four components of a copolymer (A) containing a constituent unit (I) derived from the unsaturated (poly)alkylene glycol ether monomer (a) and a constituent unit (II) derived from a maleic acid monomer (b), a specific unsaturated (poly)alkylene glycol ether monomer (a), a non-polymerizable (poly)alkylene glycol (B) having no alkenyl group, and a polymer (C) having an oxyalkylene group or a polyoxyalkylene group and a carboxyl group, which is different from the copolymer (A).
Owner:NIPPON SHOKUBAI CO LTD
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